Categories
Biohacking Chronic Disease

Day 2018 and Getting in Writing Reps In My Pressure Tube

I am a wreck. But now that everyone is discovering the value of daily writing (get in the repetition before the AI harms your skill), I have to gut it out as usual when I’ve got little in the way of cogent thought.

In an attempt to recover, I’m in a hyperbaric chamber sucking back oxygen under two atmospheres of pressure and I still can’t get my heart to stop pounding. Damned drugs.

It’s 100 degrees outside which probably doesn’t, help but even with oxygen, an eye mask, a soothing Endel NSDR session delivered by Bose noise canceling headphones, I could not get my heart rate under 100 consistently.

I wish I had a better theory than having over extended myself by traveling from mountain to swamp and desert to sea and then back again. Work and family call me, and they are not ever in the same place. It’s been a season of enormous wins but the price is being paid now.

It would seem that I’ve found my way to my first full system cascade failure since I went off my IL-17 inhibitor and onto a peptide regime with hormonal support.

I’ve had four glorious months of being able to act like I’m a reasonably healthy woman. Then I returned from a Fourth of July celebration in Utah to Montana and immediately fell apart.

My physician suggested the dreaded prednisone as well as a cycle of doxycycline. Goody goody gum drops. Both notably raise resting heart rates.

Want to see how bad? Get a look at this chart of horror and pharmaceutical malice. I woke up around my usual time and my heart has been pounding all night (no wonder prednisone makes people go nuts), my HRV registered as an 8 (average at my age should be 40-50) and this only registered as kinda in the green because I’ve had a week of it being in the mid teens. So yeah what the actual fuck. What do I even have?

The worst Whoop recording I’ve ever had

Maybe I just need to quietly let the steroids tamp down any inflammation and let the antibiotics kill off any bacteria that have decided to colonize me but I won’t lie I am terrified that those good months were a fleeting moment and this is my new normal.

Thankfully I know in my rational mind I’m in my luteal phase of hormonal horrors and I’ll get bloodwork as soon as my menstrual cycle lets me bleed.

It’s likely I’ll be in need of some new hormonal pellets sliced into my ass and any infection or inflammation is just a function of having gone a bit too hard and too fast in my glee that I can feel good again.

Categories
Aesthetics Biohacking

Day 2015 and Please Stop Me Now

I am an enormous fan of Freddie Mercury thanks to my mother’s excellent collection of classic rock. You’d be surprised at how much I’ve committed to memory from the core cannon and deep cuts that span the Beatles to Cream & Edgar Winter to Led Zeppelin.

I’m not much for karaoke, though I once tweaked my neck doing a full head bang hair whipping, Wayne’s World style, for a friend’s birthday party.

Knowing all the lyrics to Bohemian Rhapsody is clutch in these circumstances. As can go in, do a full rock opera and ease yourself out of any further obligation to participate saying “oh I had easily three times the stage time as everyone else I’ll just cheer you on!” Pro-tip for group activities amirite?

Fun fact from Reddit.
During the Bohemian Rhapsody scene in ‘Wayne’s World’ (1992) Mike Myers and Dana Carvey are both grimacing in pain while headbanging. The director, Penelope Spheeris, shot the scene for approximately five hours. Basically how I felt after my friends birthday karaoke.

Now I don’t always have the common sense to stop myself. I am a real mess at the moment as I have finally come home and I can let the whirlwind dissipate for a moment

Strained sleep with upsettingly high strain but at least it’s restorative. Now if only I could get my resting heart rate down and my HRV back up I’d be right as rain.

My Whoop is sending up red recoveries with a week of barely better yellows, as I spent a bit too much of the last few months going full Freddie Mercury “Don’t Stop Me Now” as not only was I having a real good time but I had a lot to get done.

Tonight, I’m gonna have myself a real good time
I feel alive
And the world, I’ll turn it inside out, yeah
I’m floatin’ around in ecstasy
So don’t stop me now
Don’t stop me

‘Cause I’m havin’ a good time
Havin’ a good time

It’s nice when you work and your life are aligned such that every step feels like you can only accelerate. But if we are sticking to thermodynamics, l may have allowed a little more entropy into the equation.

So give me some time to sleep it off. I’ll be in bed trying to keep my heat rate down. But being in the red won’t stop me forever. It’ll just stop me for a little bit.

Categories
Startups Travel

Day 2009 And In The Red Before The Red White & Blue

I’m deeply in the red on my energy stores. All my dashboards are flashing warning signs that I need to get in a good recovery.

I’ve up all my reserves to get myself to Utah and make a good showing to support team Valar Atomics. Ironic that I’m energy poor as all my effort posting (both online and in real life) is about a vision of cheap abundant safe and clean energy for all mankind.

What a privilege to say that Valar Atomics has been my everything for the last forty eight hours. Everyone is running on so little sleep but the outcome is a success that is undeniable. There are so many exciting interviews about our reactor and Isaiah’s from Ti Morse at Relentless (here on YouTube) to Sarah Guo at No Priors that you could spend a happy afternoon getting up to speed on the nuclear renaissance.

I hope to watch them all soon as I need some rest. So does the team. At team party after the big Nvidia event, much of the conversation turned to where everyone planned to enjoy their well deserved 4th of July break

Having served our nation by reaching criticality and generating electricity as ordered by the executive branch, this team as earned some leave. Hundred hour weeks have been the norm for many of them. This crew knows hard work. One former navy nuclear engineer joked that while the navy was tough, booting up a reactor from scratch was much harder.

Most just want some sleep but the diversity of plans was exciting. From touring Spain’s Catholic cathedrals to hiking in Alaska clearly a few had some energetic plans. But there was a lot of life basics like setting up new apartments and sleeping off an accumulated sleep debt.

I’m in camp sleep it off. Whoop is sure I’m either dying or super sick my metrics are pretty bad. Thankfully I’m going to be enjoying our nation’s birthday in the mountains with my husband and our friends. I will go from in the red to red, white and blue.

Categories
Biohacking Culture Travel

Day 2003 and Till the Sweat Drips Down Europe’s Nuts

Few topics of cultural exchange are more more humorous (and occasionally anger inducing) to me as an American with a disability than European heat waves. And Europe is in its worst heat wave apparently ever at the moment.

The persistent resistance of the French, Germans and British to installing air conditioning and updating their cities to manage climate change seems to wobble between old health superstitions and smug moral superiority. Eastern Europe and Southern Europe do not suffer from this issue.

The WSJ editorial board shared this information from France’s ecological transition agency. They are slowly being convinced that the death tolls and hospitalizations that heat waves produce may need mitigation.

The French ecological transition agency said in May guidance that AC may be necessary for the elderly, chronically ill or pregnant. But if you really can’t live without it, use it in only one room of your home, and don’t set the temperature below 79 degrees Fahrenheit. That’s because AC uses too much energy and contributes to climate change.

I prefer to sleep at 20C or 68F. This partially because my sleep & biometric tracking apps as well as my physician recommend a cold dark room to achieve the sleep required to keep my health stable. The 26C recommended by the French for us chronically ill types? It is 79 degrees Fahrenheit.

Yeahhhhh almost ten degrees warmer than my doctor recommends. No thanks you. Even at 72F if I’m down to my socks (always sleep with socks no really) and my underwear I’ll still find myself thrashing under just a top sheet. I once had my neighbors attempt to call the police on me for running air conditioning during a notorious heat wave in 2023 in Frankfurt. It was a noise complaint. Sure.

On my most recent European trip, I brought paper fans. Not electronic (though I did bring two of them as well) but the sort you languidly wave yourself with in an attempt to look cool when in a desultory mood. Which never seems to lift in this heat. It actually does look rather chic and the movement of the air helps.

I brought the pharmaceutical storage grade ice sheets used for shipping injections that have granulated particles that bond with ice to keep them cold longer.

I strap the ice inside a travel vest with dozens of pockets or wrap them around pressure points on my feet, ankles, wrist and neck with scarves when I’m particularly overheated. I’ve seen people do this with socks filled with rice and water kept in the freezer as well.

I have those goofy towels that absorb extra water and keep it cooler that I wear around my neck and head to go under the several wide brim hats I travel with. I always swear SPF 50. A sunburn is a nasty way to bring on heatstroke. I also bring my own ice trays to freeze ice cubes for both drinks & a bowl over which my hand fan blows for faux AC. I’ve dampened cotton sheets over open windows at night with a fan in to create evaporative cooling. It’s not AC but it helps. That’s why I carry two charger fans.

I will also chill wet wipes and my cosmetics. I carry small misting sprays with me everywhere (I like the classic Mario Badescu Rose). I have even mixed mint essential oil into my travel-size aloe antiseptic gel. My soup is peppermint as well to give that feeling of cool. And I always carry few rehydration sachets of electrolytes.

I’ve made friends with these techniques pretty regularly. Hydrating salts and a water bottle refill is a good conversation starter. Because as much as the French fear drafts for their health with artificial cold the Germans seem to think it’s a necessary part of life to suffer the heat (as if we don’t have enough heat in hell) everyone is suffering and needs help to get through this kind of extreme heat.

The only person who makes sweat dripping down his balls sound appealing is Lil’Jon in Get Low. And even he said at the Democratic National Convention that it’s time to get low..er temperatures. So to Europe I say get cool or you can have deez nutz. Let’s all get lower temperatures together.

Categories
Biohacking Chronic Disease Medical

Day 1945 and Always Adjusting

I am adjusting, yet again, to a new set of daily protocols in my never-ending attempt to improve my health. I am experimenting with peptides but don’t tell anyone. I’ve also got a hormone experiment in its second round.

I am trying to get healthier, but that suggests it is even an achievable goal. It would be wonderful to get back to endless working hours or even just eight hours on my feet.

Every time I make a tweak to my routines and I see a change in my biometrics, it’s becomes eventually cause for concern. There’s no stable equilibrium to be found, and I know that’s part of life, but I’d like a stable equilibrium that’s a little bit better than one day at a time or ideally a couple weeks at a time.

Take my experiment with Bimzelx. Even when I achieve an outcome like getting my CRP rates into the normal bounds, it came at a cost that is simply too high to maintain. I had four separate incisions and surgeries last year from soft tissue infections.

What good is a drug that tamps down my immune system so much that I need to always go under the knife? It was like Goodhart’s Law came to haunt me personally.

I am going off the biologic (I am 12 weeks from my last injection) and already seeing change in the wrong direction. Not enormously bad but my immune system will pop if it’s not locked down.

Yet there’s very little I can do except keep going and hope that the balance will be more manageable, as I don’t know that I could have another year like 2025 again.

I set out trying to reboot my immune system last year, and it certainly seems like it worked. But can I keep the numbers in a place that are low enough to let me live, and ideally live with fewer medications?

I am constantly working against some new tweak or some new problem, and even little gentle experiments like a Pilates reformer workout or 10 minutes on the trampoline can turn into a full-day migraine if I am not immediately able to tamp it down. Thoracic pain will pop up crushing my breathing if I take a nice slow hike in the pastures beyond our house

Categories
Chronic Disease Startups

Day 1889 and Recovering from Normalcy

I had such a lovely day touching grass (and sand) yesterday. I slowly worked through a 36-48 hours of of talking, walking, strategizing and occasionally reapplying sunscreen (I still got burned a little on my shoulders) with a friend who is preparing for big life and company changes.

These are the activities of normal life that I cherish, but my body seems hardly able to manage the strain this week. Now perhaps these activities are stressful on the mind and soul, but should they really be so physiologically taxing for me?

My Whoop is showing high strain

Now yes I am recovering from some dental work and on antibiotics but shouldn’t I be able to have a calm day that most would consider restorative? The serene peace of sitting on sandy shores should surely outweigh any areas from consequential questions of power, compute, realism and human purpose right?

I have barely been able to get out of bed today and the ten minutes of squats and planks I did to test my capacity spiked my heart rate into the stratosphere.

Which is odd as I woke up with my RHR in the 60s which is much better than usual. I only get into the 60s or 70s consistently when I am on heavy antibiotics.

The two weeks I was on Cipro recovering from surgery this summer my RHR was in the mid sixties so clearly I’ve got something going on with low grade infections.

I struggled mightily to organize my thoughts enough to write even this post. I feel I might even have it in me to go for a walk. Which is encouraging as I missed the sunset. The sunsets are obviously an event when you have a beach or far off horizon to enjoy with then.

Categories
Biohacking Internet Culture Politics

Day 1886 and Whoop There It Is

Quite a weekend for Americans and the wider Persian Gulf. Let us hope it is resolved swiftly and with the least loss of life possible.

It happened quickly. On Friday night policy types were arguing about artificial intelligence with our department of war about use cases and contacts. And then on Saturday we bombed Iran and they bombed pretty much every neighbor they have. No wonder they had a midnight deadline eh?

I’ll stick to human interest here but Chief of Staff Susie Wiles appeared to be wearing a Whoop tracker in a secure room which was confirmed by the company’s CEO by tweet.

The original concern being that some fitness trackers break NSA protocols as they have audio recording and other data recording which wouldn’t be appropriate in a dark room type the situation room.

Interestingly Whoop is approved by the NSA for use in these situations. Per the CEO the Whoop does not include a microphone, GPS, or cellular capability of any kind and has long been on the NSA approved PED list.

I myself wear both an Apple Watch and a Whoop everywhere but I rarely need to be out of the prying ears of recoding devices but it’s good to know.

Whoop’s CEO joked that given the success of the mission Susie Wiles must have had a green recovery score (quality sleep, low resting heart rate and high HRV) though I imagine she must be feeling the stress now that it’s over.

I wonder if her score worse than mine. I needed steroids and antibiotics to manage the flare post dental work and my body is under more strain than you’d imagine.

It’s somehow nice to know that the most powerful people on the planet use the same tools as I do to track their biometrics. From billionaire founders like Bryan Johnson to the Chief of Staff of the President to little old me. We all wear the same track. If you want a referral code here you go.

Categories
Biohacking Media Medical

Day 1832 and Beaten With My Own Measuring Stick

It being the new year “the new thing” to talk about is “the new you!” As if you weren’t the same person as you were a few days ago. But you have this convenient convention that allows you to decide now is the time for change.

I used to call this time of year “eating disorder season” but GLP-1s have turned down the volume on that noise. We still have New Year’s resolutions and media just love having a topic tentpole to discuss new trends, habits, and opportunities.

We may not have as much of the fat chatter to contend with anymore (thankfully) but I do have reams of biometrics and plenty of concerns about my own health so the season of changing yourself remains even if the material conditions have improved. The app chatter is still in my head.

My Whoop continues to nudge me on the “aging” metrics and which ones are hurting my healthspan the most. I hide it for a peace of mind but on the latest update it is openly admitting that it’s given me goals that are impossible for me given my limitations.

It’s a relief to see the application get better but of course I’ve know the algorithm and my limitations don’t always mix. It’s been workable when I’m in Montana walking outside but it swings my numbers a lot when I’m in a small apartment in a polluted city. It’s a “short hallway” problem.

I move a lot inside (safer and less polluted) but it doesn’t those short bursts and turns as steps so I push to get more steps counted and it overwhelms my nervous system and immunocompromised state.

I am being beaten by my own measuring stick. I always suspected this was the case but at least now Whoop can talk back and tell me just how it nudges me into worry and concern. Which is a good lesson for all of us.

Categories
Biohacking Travel

Day 1823 and Poor Percentages

I don’t know how much to trust my Whoop or Apple Watch at the moment but they agree that I’ve not had very good restorative sleep for a week or more.

I’ve never been the best sleeper and I sleep poorly when I’m on the road. I’m in the single digits for both REM and deep sleep percentages at the moment. And I seem to be spending a bit more time than I recall being awake at night.

There is something strange about being told by some electronic device monitoring your every move that you were wide awake when you don’t remember even a little bit of it.

I’ve been changing hotels and Airbnbs regularly as I make a pilgrimage across a strong mountain towns, so it’s possible I am unable to feel safe and secure enough to sleep deeply. But I’m suspicious that I’m awake as much as either device claims.

These are some bleak sleep times and I swear I wasn’t awake for 30% of my night. If I was awake you’d have seen me futzing about on Twitter. Well, at least I’d have read a book till I feel back asleep.

There is something up with my rest that makes me feel like I need to stay put for a litttle bit and get in a proper night of rest. My Whoop is showing me going from a more typical 4 hour range of rest down into the “wide awake” range of the Apple Watch over the course of the week.

And the Whoop seems to think I was awake as much as the Apple Watch did last night so I might need to accept that my brain is stewing in some toxic mix it’s not flushing through the sleep process. It also thinks I was in bed for over 10:30 hours but got barely a wink of proper sleep. My wake time was 30%

I’m going to take a break from the road trip and stay in place till I get my sleep repaired a bit. Hopefully it won’t be too hard to manage.

Categories
Biohacking

Day 1804 and 5 Years of Whoop

Tis the season of “unwrapped” data round ups as technology companies owe remind us that they have very capable data teams without unnecessarily freaking out users.

The marketers get all the glory, as everyone figures it’s a few MySQL queries gussied up with a creative hook but I always wonder what happened to the great data and behavioral science fad of the early teens. We’ve moved beyond IFTT and Zapier into natural language vibe coding. It’s a time of incredible change in understanding the data we’ve lived inside for years.

I got my fifth year of Whoop end of year marketing when I woke up today. Which was a little annoying as I wanted to see my sleep from last night but who wants to rush through the end of year review right? Finding it again can be tricky.

I keep wondering what more can we get from the hardware that knows us best. I’ve given half a decade to Whoop and mostly what I’ve learned is Covid really took 20 points of my heart rate variability.

I’ve been frustrated of Whoop’s progress in the integration of a chat AI as it seemed like any commercial LLM could analyze screen shots of the Whoop as well as their own chat did with the data it already. But tenure counts for a lot and it’s still the tool we have all relied on for half a decade now. Or at least 2% of us have worn it everyday for that long.

Clearly the data l could be used in many more way more than the management team ever seems to enable their data teams to do regularly. And I’d like to get more out of my Whoop. So being reminded of the length of use makes me wish they would deliver on that future before another year goes by.