I’ve been on the move, and in wet, rainy, and polluted weather (in other words coastal cities) where I tend to do the worst.
It is frustrating to see nearly five years of work in my journals and tracking amount to very little in the face of wet moldy environments.
It’s not a terribly pleasant topic for day 1800 and makes me feel as if I’ve made little to no progress on moderating my immune system.
I’m particularly upset as it’s bad enough I chose a steroid course. I am too afraid of getting an infection. I loathe prednisone. It works so well. It is like a hammer on inflammation.
Prednisone crushes every inflammatory condition instantly. Red itching oozing welts in a matter of hours. But I can speak from hard experience that even though it stops a cytokine storm in its tracks, it leaves you crazy and fat in quite short order.
I am simply terrified of picking up a skin infection as I’ve had a doozy of a year dealing with them in areas delicate and unusual. It’s been horrifying to have issues with eyes, an incision site and abscesses in even more personal areas.
It seems safer to use the hammer before an area of open skin can be found by an invasive species just looking for somewhere wet and broken. I pray it was the correct choice.
For someone with clear skin on my face (not even a humble brag), I spend what feels like irresponsible amount of time and energy on my skin health. The rest of my dermis is not as tractable as my face. I’ve been fighting eczema my whole life.
This year has been a particularly challenging, as my the IL-17 immune suppressant Bimzelx, I take for my ankylosing spondylitis and psoriatic arthritis (it’s eczema on the inside), has left me almost catastrophically prone to skin infections.
I’ve had maybe 3 weeks without a disaster (and I traveled) though have still needed doxycycline so I’m optimistic.
I am hoping I can rack up a few more weeks or maybe even multiple months without needing to slice an abscess, manage a deep tissue infection, or get a subcutaneous skin infection.
I do have a new weapon in my battle to keep my skin healthy. I recently acquired a new deep infrared cosmetics mask from Beauty Pie that they are calling “medical grade” but mostly means it has one longer wavelength than their previous mask offering.
Medical-grade LED mask proven to improve the overall skin complexion
Using 1070nm – the deepest penetrating wavelength used in at-home LED devices to date – to reduce under-eye bags and puffiness, and smooth texture and tone
Helps the skin look fresh & hydrated. Using 830nm – supports the skin’s natural restorative and healing function – to boost circulation, improve blood flow, and increase oxygen
Skin looks plump & glowing. Using 630nm – enhances the production of collagen and reduces redness – to leave skin radiant and hydrated
I don’t know if it will do much but the longer wavelength is an improvement on their past mask which required something closer to 4 months of continuous use to see results and I was simply never off of antibiotics that interact negatively with red light long enough to get any results. Theoretically I should see results in a few weeks with the longer wavelengths.
I can’t recommend it yet as I just got it and I’ve only used it twice but I used it on my face, my neck, my left butt cheek where I had the infection from inserting testosterone pellets (long story if you missed that one) and on my scalp to see if I can stimulate some growth on my scalp as I shed a lot of hair this year from the stress.
That’s about 40 minutes of mask time so no joke but also pretty amusing. I hope I can use it enough between antibiotics rounds for a win as infrared is meant to do a world of good for pain and inflammation in addition to cosmetics so I’ll use the heck out of it while I can.
The days becoming shorter has hurt my attempts at getting out in the sun for a walk every day. This matters to me as I’d like to get regular readings of my V02 maximum and my heart rate. I rushed out without sunscreen to get in a mile.
I hit an important milestone in my current biohacking regimen this week. I made it to my 40th session of hyperbaric oxygen chamber therapy or HBOT. I began on September 13th and did session 40 on November 20. I only traveled once during this period (a five day trip) so I could have fit it all in within a two month period but I was consistently doing two hours a day.
I intend to get bloodwork for comparisons next week, but in some ways this was a terribly experiment period. I had a small procedure to insert testosterone and estradiol into my left buttock which turned into a saga when I got a skin infection. Not the procedure’s fault and I’m glad I did it as my numbers are already better.
Fortunately HBOT is renowned for healing soft tissue infections so if I was going to suffer for having compromised immune health across my skin biome, then at least I had the state of the art treatment available.
We didn’t purchase the HBOT for its skin benefits. In fact, I didn’t even know I’d be have skin immunity issues. They began with my new IL-17 inhibitor which I started in January We’d acquired the HBOT around the same time but I had no idea how challenging Bimzelx would be. It could have gone worse.
We had originally acquired the HBOT as several of our friends and acquaintances had succeeded in managing impressive inflammation rate reductions as well as progress with a slew of autoimmune issues from long COVID to mold toxicity. The kind of troubles we only test in fancy labs with extreme athletes or the enterprising technology brother.
My wound has mostly healed save a small lump, my V02 max has improved despite virtually no exercise (hard to do much cardiovascular exercise with an infection in your posterior chain) and I have overall found the balance of improvement in my energy and pain to be significant.
Thanks for noticing Whoop
If I could just get a month without a health crisis where I have enough energy to workout consistently I just might make some progress. So if I disappear for a bit that will be what I’m doing. Once I’ve got bloodwork I will share obviously.
The volume of communication we receive digitally has risen to deafening levels. I’m shocked we aren’t all in a civilizational stupor muttering “mawp” like the cartoon secret agent Archer.
As we attempt to balance the barotrauma of the increasing volume of dings, pings, tings and Slack bings trying to reorient our attention towards them, the temptation is level the pressure explosively. Shut up!
The noise is bearing down on us relentlessly. Just when we think the pressure might equalized and we have adjusted to the din, a new chime will force a recalibration.
MAWP!
Our phones become dysbaric monsters. The ambient pressure disorder that is leveling your attention span to the cacophony of alerts and aggravated existential noise leaves us deaf, dumb and disoriented.
Different people cope with this in different ways. Many of my friends have committed email bankruptcy including me. Some people make big claims of having screen free homes. Others go to physical therapy or osteopathic craniosacral specialists for cervicalgia. Isn’t it nice to know your text neck is killing you even if the tinnitus and vertigo doesn’t get you first.
This is all to say that my Signal Mobile application inexplicably stopped working this morning and the silence is causing me some degree of anxiety. If I were a woman with fewer scruples I’d consider it disabling.
Alarmingly, because I’ve been forced to mute virtually every other channel of communication to avoid the noise, this means it’s been largely impossible to get work done.
Hopefully I find a solution soon. I rebooted my phone, cleared my cache and updated to the new iOS. Nothing works. I’m afraid that I’ll be losing the one channel that actually functions for me.
If not, you may very well not hear from me again. Twitter direct messages still work. If you are looking for me check the nearest ear, nose and throat specialist. If I can’t fix my ankylosis in my thoracic maybe I can improve my posture in the meantime. The worst case scenario will be installing WhatsApp but I’ve not given in to that nightmare scenario just yet. I’m running silent in my attention submarine but I’ll have to resurface at some point.
I feel like I got quite a scare and yet you’d think I’d be used to it, as this is all downstream of the interleukin-17 inhibitor that I changed onto at the beginning of the year for my autoimmune condition.
Every single quarter, and in some cases every other month this year, I have had some bizarre skin infection resulting from otherwise pretty benign situations. An infected gland in my eye (twice!) an abscess that turned into a deep tissue infection, and a tiny incision that allowed in a subcutaneous infection all rocked my world.
As much as I am thrilled to see all of my inflammatory numbers rolling in to baseline normal, I just don’t know if I can sustain having a health crisis this frequently for a medication that is supposedly working. It’s working at an extremely high cost to my sanity and body.
And you might say, “Well, the numbers don’t lie.” And I’d agree. But there are many other factors I have to consider, not the least of which is that healthcare access in America is so bad that I have managed two of the four crisis points with medical tourism abroad.
I am going to give my IL-17 inhibitor a full year as dosing on and off biologics is no easy matter and the compounding effects are quite real. But I do very much wonder if in order to go forward I must turn back.
And then it seemed I took a turn six days further on. Perhaps some trauma from the lidocaine and epinephrine induced enough of altered window of immunity that some bacterial weaseled its way in the wound and viola a subcutaneous infection called cellulitis.
I was put on two different antibiotics and we figured it would clear quickly. That was incorrect And it has been a slow healing process
Barely improving day by day. And I had somehow made the decision the night before the procedure that I would just waltz into a new beauty shopping blog as the holiday season warmed up. So that was perhaps bad luck on my part. And has slowed me down on something I was doing for some joy so I hope I didn’t let anyone down. I am muddling through.
Today I got an ultrasound on the wound after a fever spike and did a number of blood tests to see where my white blood cells and inflammatory markers were at.
The local hospital was having computer troubles which meant trouble scheduling an ultrasound but we managed to find another imagining clinic this morning.
Back at the hospital for bloods (they do walk ins for blood draws) they still appeared to be having issues with computers. “Your insurance isn’t recognized” was the verdict thirty minutes after using it at other lab. That made for a chuckle but we got it done.
The results are already in and we seem to be looking at healthy epithelial tissues and my CRP and Sed Rates were not elevated. Of course, half the reason I am worried is I take an immune suppressant for chronic autoimmune inflammatory condition.
It seems to manifest frequently as skin infections. My old drug wasn’t nearly as effective but it also didn’t have side effects. S
Hopefully slowly and with lots of protein and rest I’ll be healed and can spend my time on work and my pet beauty blog.
And tomorrow I’ll cross my 30th HBOT treatment mark so maybe it can make progress on building me up instead of dealing with a flesh wound. Which is actually just damned good luck on our part.
It has not been an easy year for me or my family. The struggle to find a path to a sustainable place of health feels harder than ever.
I am living in some type of thermodynamic hell. Everything I try comes with equally forceful reactions and I wish I could say more of them were positive.
Even when results look positive they have high costs that make me reconsider if I should have done it at all. Switching my immune suppression drug put my inflammatory markers in the best place we’ve seen them in years.
Alas it is so effective that I’ve had four major skin infections in 2025 of which four required going under the knife. And the fourth was caused by a small incision that was considered so safe and routine we almost didn’t consider antibiotics at all.
I just so badly want something to work in a way that doesn’t come with staggeringly high costs. Normally I’d link around to all the relevant posts but I just need a break so I’ll leave it as an exercise.
But can you imagine anything more depressing than having an infection on your ass? I sure can’t. I am stuck trying to keep pressure off of it while working on all the various projects of life and I am a slow healer.
I don’t even get to see if the HBOT is doing anything for my main concerns, as if it is we are only going to see it when I clear this crazy infection.
I suppose the good news is that one of the best treatments for high risk wound care is actually hyperbaric oxygen therapy so the positive and the negative are at least balanced.
I’m a bit hard up today as my recovery from my latest adventure in biohacking has had more twists and turns.
I am incredibly prone to subcutaneous and deep tissue infections from even modest and safe procedures. It seems this will simply be my reality permanently if I stay on the very effect anti-inflammatory medication.
I keep hoping I’ll adjust to the Bimzelx and the skin infections will be less of an issue but I’m on my 4th skin trouble of the year and I’ve only just reached what’s considered a full loaded dose.
I really don’t know what to do about it as it’s a major full year long process to change a biologic and adjust to the dosing so I may have to live with it. My inflammatory markers are the best they have ever been it’s just that I’m constantly getting some new skin issue.
So I’ve switched up the antibiotics to be extra careful on this healing but my brain is beyond fuzzed, I’m in pain, and I’m quite tired so I’ll just have to let today be what it is and pray the new antibiotic gets me to a better tomorrow.
Now you might think all that walking around would leave your body feeling invigorated, and honestly it did, but we finished our grand tour by eating at the Costco food court. Now there are probably ways to eat healthy there but not how we did it.
We went for the classics including the dollar fifty hot dog and soda combination (a bulwark against inflation that has stood longer than seems possible) a slice of pepperoni pizza, a strawberry smoothie and a chocolate chip cookie. I had the pizza, some of the smoothie and half the cookie while Alex had the hotdog, a root beer, the rest of the smooth and a little bit of the cookie.
We didn’t feel immediately worse but we woke up today with what I’d qualify as a hangover. We can enjoy the above roasting as we generally don’t eat junk food and when we do it’s in more of the local beef category than the hyper processed and hyper preserved category.
Before you think this is a show of virtue, this preference never did anything for my aesthetics or metabolism, it’s just that it always makes me feel bad.
I am quite sensitive to preservatives and refuse to eat most forms of American bread and most varieties of prepared meal. No matter how good the ingredients are, the preservatives just do not agree with me.
It’s not that I’m a healthy eater naturally so much as hyper palatable foods are often hyper preserved foods and that sends my histamine response soaring into cytokine storms. So it’s no wonder I woke up feeling hungover.
I did real damage to myself as Bryan pointed out. We had a lovely time and I like to think the joy and happiness reduced our cortisol enough to bring us some balance. But it was easy to quit drinking for the same reason as it is easy to quit fast food. You feel like shit afterwards.
One of the most amusing fights I recall my parents having was my father taking my kindergarten class to tour a Carl’s Jr kitchen. They gave us a kid’s meal at the end, and while I turned up my nose at the burger, I did eat the french fried potatoes. My very crunchy and wise mother was not happy. “Now she will have a taste for French Fries!”
And damned if she wasn’t right. I still haven’t ever eaten a fast food hamburger. The idea of it is revolting to me and I’ve no clue how that came to be programmed in me. I may be one of the few people in America who has never eaten a Big Mac. But I love french fries. And good potatoes fried in a decent oil never leaves me feeling awful. But bread that doesn’t go moldy? That gives me a hangover every time.
You might want bring towel though, as our handcrafted Finnish sauna will need some use before the cedar is completely smooth. Yes, that’s right, the MilFred family Yellow Barn now has a sauna. And she is a beauty. Just check out the view we picked for her.
Alex and the wonderful family who built the cedar sauna structure placed her under the back awning of the big yellow barn today. Wiring and electronics are underway as I write.
We’ve been slowly but surely turning our barn into our ideal wellness center both for our own use and eventually for the wider community as well. We are privileged with skills, capital and loads of very expensive personal experience with chronic illnesses.
So naturally as geriatric millennials it is always our instincts to turn our pain into something useful and also if we are lucky pay back the expenditures and turn a profit. Which we can then reinvest. It’s the circle of life for a generation who found the circle of life to be a tad more inflationary than expected.
The man of action putting the finishing touches on the electronics. We don’t have anything in our home systems connected to the cloud, so he built his own fully local controller with ESP32 as the brains, 60a 240v contactor for heater, RGBW LED controls UI/ final control via Home Assistant and HomeKit. You can snag the code on GitHub
In true MilFred fashion, we are building and testing everything all on ourselves. An n of 1 is good, an n of 2 is better, and if you’d like to test it out hit us up while it is a work in progress. Build in public and beta test with your friends.
Tucked under the awning of the barn so one can easily pop in from gym, HBOT or cold plunge to warm cedar comfort and mountain views
We’d like to ultimately build a space for healing, relaxation and training for those who prefer time tested modalities like heat, cold, oxygen and pressure.
Friends and family can come and test out our now very impressive range of equipment as we build this all out.
We have one of the few hyperbaric oxygen therapy chambers available outside of hospital use in the region. You can pressurize to 2 atmospheres and set a range of parameters for a range of treatments. I use it for my inflammatory condition while Alex is treating the remains of long covid. You’d be shocked what pressure and oxygen can do.
Our hyperbaric oxygen therapy chamber
If you want a work out get in some squat reps in our power cage, take a swing at the punching bag or lengthen your spine on our Pilates reformer. You can even climb around on the rock wall built into the the barn ceiling (not even kidding that is the work of the previous family).
If you are looking for a spa day you can have a sweat in the sauna, do red light therapy on your face, chill out on a PEMF mat, and hopefully soon take a dip in a cold plunge. Though if you are ambitious you can sprint across the front pasture and jump in our pond but I’ll warn you that the ducks might not love it.
The pond is fed by a creek that comes from the canyon above our house
The point being that we are building by hand and through personal experience something that improves our lives and others and that’s a pretty hot thing to do. Don’t worry, we will provide towels and robes if you do indeed take off all your clothes. Just come on over and try it out.
