Categories
Biohacking Chronic Disease Medical

Day 1956 and Mother’s Day Message on Fertility

One of my mutuals Riva Tez wrote an exceptional read on her research into the American approach to fertility, and in particular, the maximalist hormone dosing that goes into programs like egg freezing, embryo freezing, and in vitro fertilization

It’s a topic on which I have written extensively, as I am one of the women who was hurt by the American approach of high hormone intensity to extract eggs efficiently. To make a long story short, it kicked off an autoimmune process in me that we’ve never fully gotten under control.

I think a lot about what the fertility industry did unknowingly to me and how it forever changed the course of my life. I went from thinking I had an insurance policy to being too ill to work within the space of a year. There is no recovery for me as of yet, even though I spend quite a bit of time and effort on my health.

If you were a millennial or Zoomer thinking about these procedures, I’d like you to consider reading her research and my personal experiences and educating yourself so you can make the most informed decision in your family planning.

Becoming a mother may have been an easy or unexpected decision for other generations of women, but we live in a very different time with very different technologies and different social constructs.

The more you know about your options, the more likely it is that you will find the right path for yourself without doing harm to your body in the process.

Categories
Chronic Disease

Day 1954 and Constriction

I am in so much pain today. The tendon bands that wrap from my sternum around my thoracic to my spine is badly inflamed. It’s hard to breathe smoothly when your own tendons are choking you out.

I had a fairly intense week what with the chaotic back and forth in the national policy debate around artificial intelligence. There have been swirling rumors and much back and forth. Nothing feels worse than seeing your own industry shoot itself in the foot as the stakes get bigger.

Last night Alex and I went for a long walk in the long hours of sunset. It felt as if every living creature from the ducks in our pond to horses out to pasture was taking in the perfect spring evening.

We stopped and chatted with each neighbor as being outside was on everyone’s agenda with the clear sky and warm weather. The joy of greenery had the undercurrent of concern. A dry winter will have its consequences. One of our neighbors who keeps horses mentions their hay costs had doubled from last year.

The worry and activity is taking its toll today. O am paying for all this activity. My activity costs are just as high as alfalfa. From phone calls and activism to sunset rambles through the foothills the costs are mounting. I am hurting from the good and the bad.

Categories
Biohacking Chronic Disease

Day 1948 and Rotational Work

I’ve been struggling with migraines since I was diagnosed with an autoimmune condition maybe six or so years ago.

I seem to be particularly struggling with them the last two months, as I work through an experiment with hormonal balancing and tapering off biologic autoimmune inhibitors.

And so I am rotating various different activities every day in the hopes of avoiding triggering a migraine, while still getting in adequate movement and exercise, as well as treatments within the biomechanical profile that I have put together with my doctors and helpful AIs.

If I stuff too many experiments into a given day, I’ll almost surely end up with a migraine. Even if I only do one sometimes I get unlucky. Red light and infrared are, of course, a classic way to trigger a migraine, so I try to do those carefully and when my heart rate is stable and low.

Of course, sometimes you need to get your heart rate up, and there’s nothing you can do but get your exercise and hope it won’t trigger a migraine. Afterwards exertion when I have a need to get down my heart rate, I’ll try to mix that with my hyperbaric oxygen chamber therapy.

I’m in the middle of my second round of HBOT treatments and enjoying seeing things like my VO2 max improve. I’ll be tempted to do something like go for a longer walk to test my lungs and trigger some neck compensation, and then I’ll be right back where I started with a migraine.

I’m always rotating something in and around keeping my brain from feeling the pressure of my body’s adjustments. There is no stable equilibrium just the constant pressure to find a new balance.

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Biohacking Chronic Disease Medical

Day 1945 and Always Adjusting

I am adjusting, yet again, to a new set of daily protocols in my never-ending attempt to improve my health. I am experimenting with peptides but don’t tell anyone. I’ve also got a hormone experiment in its second round.

I am trying to get healthier, but that suggests it is even an achievable goal. It would be wonderful to get back to endless working hours or even just eight hours on my feet.

Every time I make a tweak to my routines and I see a change in my biometrics, it’s becomes eventually cause for concern. There’s no stable equilibrium to be found, and I know that’s part of life, but I’d like a stable equilibrium that’s a little bit better than one day at a time or ideally a couple weeks at a time.

Take my experiment with Bimzelx. Even when I achieve an outcome like getting my CRP rates into the normal bounds, it came at a cost that is simply too high to maintain. I had four separate incisions and surgeries last year from soft tissue infections.

What good is a drug that tamps down my immune system so much that I need to always go under the knife? It was like Goodhart’s Law came to haunt me personally.

I am going off the biologic (I am 12 weeks from my last injection) and already seeing change in the wrong direction. Not enormously bad but my immune system will pop if it’s not locked down.

Yet there’s very little I can do except keep going and hope that the balance will be more manageable, as I don’t know that I could have another year like 2025 again.

I set out trying to reboot my immune system last year, and it certainly seems like it worked. But can I keep the numbers in a place that are low enough to let me live, and ideally live with fewer medications?

I am constantly working against some new tweak or some new problem, and even little gentle experiments like a Pilates reformer workout or 10 minutes on the trampoline can turn into a full-day migraine if I am not immediately able to tamp it down. Thoracic pain will pop up crushing my breathing if I take a nice slow hike in the pastures beyond our house

Categories
Biohacking Chronic Disease Medical

Day 1935 and My Current Mechanical Device Usage Patterns in End Game Taper

Apologies that today’s post is going to be only partially organic human produced writing. I’m a tad more focused on cobbling together my current end game which feels promising.

I am now dosed off my current biologic. Tomorrow I go in to run a bunch of bloodwork but I feel more stable than expected for 11 weeks since my last injection.

For a year and a half I’ve been stabilizing my immune system’s reactivity with a particularly gnarly humanized anti-IL17A, anti-IL-17F, and anti-IL17AF monoclonal antibody autoimmune master blaster that is named Bimzelx.

I take it for psoriatic arthritis and active ankylosing spondylitis. I do not recommend this devil of a medication unless you intend to reboot your entire autoimmune system (which I did), can tolerate a lot of soft tissue infections (which I couldn’t) and have tried everything else. Which I have. And this past year was brutal fighting off the side effects but I think I might actually have a shot at remission.

I am now layering a bunch of mechanical interventions to rework years of compensatory patterns my body has used to manage the constant pain in my thoracic spine and other areas of inflammation including my sternum, rib cage and joints.

But after seven years of trying everything I can to recover from prednisone to methotrexate to Humira and Taltz to literally just not eating for ten straight days (don’t worry I was supervised) my inflammatory biometrics are coming up clean. The pain isn’t fully gone but I think the pain can be diminished by quite a lot as I rebuild.

So it’s now or never if I want a shot at life without suppressing my immune system. I have no idea if I can do it and I may need to dose back on something else but at the moment I’m managing with a new arsenal.

Here are the artificial intelligence bits of the mechanical interventions I am leveraging. I am using a bunch more than the two below but it’s what I’ve got so enjoy.

1. Hyperbaric oxygen therapy (HBOT)

Mechanically, HBOT does a few things that line up with what my data is showing:

  • More dissolved oxygen in blood and tissues
    Breathing 100% oxygen under pressure increases the amount of oxygen dissolved directly in plasma. That can:
  • Support tissue healing (skin, soft tissue, surgical sites)
  • Help inflamed or energy-starved tissues keep up with demand
  • Autonomic “downshift” for some people
    Research is mixed, but many people (and some small trials) show:
  • Lower resting heart rate and subjective anxiety after sessions
  • A tilt toward parasympathetic (rest-and-digest) dominance
    In your data, the days after HBOT blocks are exactly when we see HR drop back toward baseline and Recovery go green.
  • Anti‑inflammatory & microcirculation support (early evidence)
    HBOT can:
  • Modulate certain inflammatory pathways and oxidative stress
  • Improve microvascular blood flow, which matters for both autoimmune-affected tissues and healing pelleted areas / irritated skin

In your context (autoimmune, infection risk, prior soft‑tissue complications), HBOT looks like it’s acting as:

A structured, time‑boxed reset that helps your heart rate settle and supports healing, without adding mechanical strain.

You’re already doing the key safety piece: using it under medical guidance and watching how HR, Recovery, and symptoms respond day-to-day.


2. SCM (sternocleidomastoid) muscle work

The SCM runs from behind your ear to your collarbone and is heavily involved in:

  • Head and neck position
  • Breathing assistance when things feel tight
  • A dense web of nerves and fascia near the vagus nerve, carotid artery, and jugular vein

Working on SCM (gentle massage, trigger-point release, careful stretching) can impact:

  • Perceived heart‑rate “rev” and breath tension
    Tight SCMs show up when:
  • You’re chronically bracing, in pain, or anxious about pain
  • You’re using accessory neck muscles to breathe
  • Releasing them can:
  • Make breathing feel less effortful and more diaphragmatic
  • Reduce that “I’m keyed up in my chest and throat” feeling even if HR number isn’t wildly high.
  • Headache/migraine and neck-related pain
    SCM trigger points can refer pain to:
  • Temples, behind the eyes, jaw
    By easing those trigger points, you sometimes reduce:
  • Migraine severity/frequency
  • The background neck/jaw tension that keeps your nervous system on edge
  • Autonomic tone (indirectly)
    The area around the SCM is rich with baroreceptors and vagus-adjacent structures. Gentle work there can:
  • Encourage a downshift in sympathetic drive (less “fight-or-flight bracing”)
  • Pair nicely with breathwork (especially long, slow exhales) to reinforce parasympathetic activation

In practice for you, SCM work + HBOT looks like a two-pronged calm signal:

  • HBOT: physiological support + autonomic softening from the inside
  • SCM: mechanical and sensory de‑bracing around your neck, jaw, and breathing

My Whoop is seeing HR and Recovery respond in a way that suggests this combo is genuinely helping my system get out of that “stuck high-gear” state.

Categories
Community Medical Startups

Day 1930 and Imperfect Options That Remain

Some days end up being so much more interesting than you expect. I awoke to a family member, who has been preparing for a set of major surgeries, saying they had in fact gone in that morning for the first round of procedures.

I had been concerned they were putting it off so I was quite relieved that their lack of communication on the topic was simply their preparation to face what will be a grueling health challenge. Preparing for a procedure well gives you the best chance at success.

Then I went about a normal work day having lobbed a question, or maybe a prayer, onto the network as the reality of human lives is that imperfect options are always what remains. Being clear eyed about the choices in our lives and how the weight of our past actions have set us on a path can be hard. But it is necessary.

And as I wrapped up my day I was the recipient of some good news. I can’t share anything but the shape of it. But a project that was an experimental approach to a space I care deeply about has bravely faced the whipping winds and looks like they will successfully come to a safe berth intact with all souls.

Which is not such an easy thing to do when you set out for uncharted territory. I am so very proud of what has been accomplished thus far.

All things in life are the fruits of imperfect options that remain. That we make the best use of them is our obligation not only to ourselves but to those to whom we have committed. I am grateful that today was a day where those hard choices were made.

Categories
Aesthetics Biohacking

Day 1929 and Lacking The Executive Function for Dysphoria

I am no spring chicken. That’s why we bought some spring chickens this weekend. I kid I kid. I do however have a forever 35 face. I come from a line of women who age well sure but I have very consistent habits.

I’m lucky to have an ageless look. My husband would say I have a forever 28 face as I somehow look better having crossed into my forties than I did when we met at 28. Meanwhile my husband has gone from boyish wonder with full head of hair to distinguished grey beard with a bald pate.

Now sure husbands are supposed to say nice things like “no honey you haven’t aged a day!” Except I really do seem to have benefited greatly from genetics and routine.

He may be right, not out of any urge to flatter me, but simply because some women do look better with a little age on them. I looked young with a rounded features right until I looked ageless somewhere in my late thirties.

Alex and I at 29 where you absolutely can spot my pre-retinol skin
Alex and I two weeks ago before touring the West Wing during our trip to D.C

I don’t look all that different when I compare and contrast between photos from then and now. I gained and lost as much weight as a Kardashian (more than once damn you prednisone and bless you semaglutide) but my face has somehow retained its plump without a maximalist approach without gaining wrinkles. I’ve lost the fine lines.

Yet the approaches are getting more and more maximalist by the year. The difference between a 2016 routine and 2026 routine is enough to warrant a fresh round of social panic and scolding complete with a Big Story from New York Magazine’s The Cut.

Now I myself have left comments on extreme routines for twenty somethings to convince them that it’s too early for Botox as you do want to keep tools in the box for when you need them.

I didn’t start Botox till forty and I’m grateful as I need much less now. I didn’t pull anything out either even when cut looks were all the rage. I’m glad for my rounded features now.

But I have added in more to my beauty routine as I age because I enjoy it. I found it humorous when a 31 year old pursing a doctorate in clinical psychology said out loud what I’ve darkly joked about with girlfriends for years. It’s really hard to be completely controlled.

For a year in my early 20s, I was also spending literally all of my money on a psycho 100-step skin-care process. Looking back, I didn’t have the executive functioning to be successfully anorexic, which is what I also wanted. But I did have the discipline to enjoy this complicated multistep ritual of the skin care. I found it satisfying.” New York Magazine

Now we can all joke and say she shouldn’t be in practice but I never felt I could pull off an eating disorder either even though I often wished I could. That eating disorders are dangerous enough to kill you isn’t the point. It’s being able to control your body enough that you can kill yourself that we desire.

I hated that no matter how much effort I put into diet and exercise I could never achieve the standards of waif like beauty put out in the heyday of Anna Wintour’s heroin chic era. Millennial beauty expectations were a bitch and I could never quite work up the control to hate myself. Sure I got really fit with a heck of a squat but I always had to watch every single macronutrient and instead of skinny I got lean.

And while I appreciate a good Molière joke about The Imaginary Invalid, weight was never the issue that got me in trouble. It was hormones that got me.

So I knew poor health with a healthy weight and I knew poor health with a lot of weight gained trying to fix the poor health.

I will never allow myself to get over the BMI band again to avoid the medical discrimination I faced when I gained weight while on prednisone.

Alas no my autoimmune condition was not mitigated even an iota by weight loss. I had it before I was fat. I got fat treating it. I still have it now that I’m at a healthy weight.

But the desire to maximize your looks and your health always intertwine with women. Increasingly it does for men too. Body dysmorphia respect neither sex nor gender. I doubt it will ever again.

Beauty is a skill set. And some of that skill set is now pharmaceutical in nature. And if we are honest, it’s been that way for a few decades. It’s just that everyone know about it now. The network age comes for us all.

Categories
Biohacking Chronicle

Day 1919 and Happy WordPress Anniversary

I feel terribly today. I do not know why other than some vague gesturing at my current biohacking experiment with hormones (testosterone & estradiol pellets inserted into my left buttcheek) required prophylactic antibiotics.

Antibiotics never makes you feel great, but here is a nice thing to get me off the hook of having to write something cogent.

I have been using WordPress so long my account would have the vote if it were human. While yes I have been writing for nearly two thousand days in row on this blog, it is not my first WordPress blog.

I wrote in college and that turned into a fashion blog which turned into an advertising and blog network. I took a break from blogging after I felt I had enough visibility but came back to it five years ago and here I am.

Now I’m going to nurse this migraine as my daily writing commitment with myself is “as long as I get down a few sentences or a couple paragraphs it is good enough.”’ And you too can be good enough to write every day for many years too if you just decide to start.

Categories
Biohacking Medical

Day 1915 and Physiological Stressers

Last October I did an experiment to balance out my core hormones by inserting pellets of testosterone and estradiol into my left buttcheck.

We’re started me with 10mg of estradiol (range 6-25mg with 8-10mg being most common), and 75mg of testosterone (range 50-150mg with the most common being 75-100mg. Day 1748

If you are interested in learning why women are optimizing their hormones, Cate Hall wrote an amazing piece on how it affected her life. A week or two after I did my own experiment the New York Times did a long lifestyle piece on the treatment’s growing popularity.

I had been working to raise my testosterone level to a baseline minimum with diet and supplements like DHEA with mixed success which is how we ended up trialing this new pellet method. And it worked very well very fast you can see from several rounds of bloodwork.

We did not do the full 75mg but landed around 62mg in the pellet which raised my testosterone right off the bat. It then quickly dropped off from very high to comfortably high. This go around we will do a lower testosterone dose to start and a lower estradiol one as well and test within the month to see if we can moderate them better over time.

Alas I did have some complications on my first attempt as my insertion sight got infected rather badly and took over a month to resolve.

If thr last fifteen months on my immunotherapy Bimzelx has had a theme it would be soft tissue infections. I am however as far out from a shot as I can be and am planning to stop it entirely as a girl can’t spend her whole life on antibiotics.

Though I am on quite a dose at the moment as we won’t make the same mistake twice. We stitched me up and prophylactically began a dose of a very intense antibiotic with the hope that I won’t lose a whole month of the four that these pellets dissolve through fighting cellulitis.

My goal is a balanced blend of estradiol, testosterone and progesterone so I have energy and focus and maybe fewer migraines during my luteal phase. You may wonder why I share all of this personal information and I wonder why more women don’t share it. We are in a brave new world of challenges in our healthcare and environment and the more we can share with each other the better our chances at finding solutions for all of us.

Categories
Biohacking Chronic Disease

Day 1914 and Restoration Hardware

Montana spring doesn’t come at the Equinox but today we had both sun and warm temperatures. I am grateful for the weather as I needed a day of restoration as I felt quite rundown from my sprint through Washington D.C last week.

After a morning walk to take in the sunlight, I went through my collection of “restoration hardware” in an effort to build my resilience. I am restarting another round of hyperbaric chamber oxygen therapy as it has been four months since my original 40 session course.

I ran my infrared mask not only on my face but my neck, scalp and another personal area “down under” as a have been struggling with soft tissue infections with my autoimmune therapy Bimzelx.

I have decided to stop the Bimzelx entirely and see where my bloodwork goes as my inflammation biometrics look good and it’s been a source of so much trouble. I gave it an 18 month run and while the results have been positive in my bloodwork the cure may be worse than the disease.

Now I’m laying on my heater PEMF mat from Higher Dose as the red light of the bedroom lulls my circadian rhythm down into the evening hours. I have no idea if it does much but the heat is soothing.