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Biohacking Chronic Disease

Day 1761 and Give Me A Break

It has not been an easy year for me or my family. The struggle to find a path to a sustainable place of health feels harder than ever.

I am living in some type of thermodynamic hell. Everything I try comes with equally forceful reactions and I wish I could say more of them were positive.

Even when results look positive they have high costs that make me reconsider if I should have done it at all. Switching my immune suppression drug put my inflammatory markers in the best place we’ve seen them in years.

Alas it is so effective that I’ve had four major skin infections in 2025 of which four required going under the knife. And the fourth was caused by a small incision that was considered so safe and routine we almost didn’t consider antibiotics at all.

I just so badly want something to work in a way that doesn’t come with staggeringly high costs. Normally I’d link around to all the relevant posts but I just need a break so I’ll leave it as an exercise.

But can you imagine anything more depressing than having an infection on your ass? I sure can’t. I am stuck trying to keep pressure off of it while working on all the various projects of life and I am a slow healer.

I don’t even get to see if the HBOT is doing anything for my main concerns, as if it is we are only going to see it when I clear this crazy infection.

I suppose the good news is that one of the best treatments for high risk wound care is actually hyperbaric oxygen therapy so the positive and the negative are at least balanced.

Categories
Biohacking Chronic Disease

Day 1757 and Best I Can Do

I’m a bit hard up today as my recovery from my latest adventure in biohacking has had more twists and turns.

I am incredibly prone to subcutaneous and deep tissue infections from even modest and safe procedures. It seems this will simply be my reality permanently if I stay on the very effect anti-inflammatory medication.

I keep hoping I’ll adjust to the Bimzelx and the skin infections will be less of an issue but I’m on my 4th skin trouble of the year and I’ve only just reached what’s considered a full loaded dose.

I really don’t know what to do about it as it’s a major full year long process to change a biologic and adjust to the dosing so I may have to live with it. My inflammatory markers are the best they have ever been it’s just that I’m constantly getting some new skin issue.

So I’ve switched up the antibiotics to be extra careful on this healing but my brain is beyond fuzzed, I’m in pain, and I’m quite tired so I’ll just have to let today be what it is and pray the new antibiotic gets me to a better tomorrow.

Categories
Aesthetics Biohacking

Day 1756 and Oops I Did It Again

Oh baby baby! So it seems as if, in my infinite wisdom, I did not pay enough attention to the early warning signs from my Whoop biometrics and I did indeed need to worry about the fun and games of a subcutaneous tissue infection.

I swear that this IL-17 inhibitor drives me nuts. Despite its impressive effect on my inflammatory biomarkers, it leaves me very susceptible to skin infections. And I have to be constantly vigilant to the first signs of an issue.

I’ll be fine. I did in fact catch it before it turned into anything serious. Where I am at it’s easily treatable with a short antibiotic course that may formerly be prophylactic. My wound area had not shown any signs of spreading nor was I running a fever or otherwise exhibiting other signs of serious infection.

I just had crappy HRV numbers and high resting heart rate three days in a row and it’s not worth risking it. I threw back some basic antibiotics last night and woke up with a normal heart rate again. My HRV is coming up just a little more slowly. Glad I didn’t wait as this isn’t worth any amount of risk to me.

I comforted myself by working on my beauty blog where I’ve got routines coming along for founding subscribers and a fresh post about Shrinkflation at Sephora and a minimalist men’s routine on sale at Amazon.

Retailers are a bit twitchy and everyone needs to be shopping early is the message we are getting everywhere. It’s a weird time. Or at least the retailers need to encourage the top 10%. So if that is interesting to you go subscribe as I’d love to have you in my strange beauty shopping blog meets the business of appearance.

Or if you are feeling adventurous for an honestly embarrassingly low fee I’ll put together a custom routine for you from my sample library or go full autistic and decant you the perfect mix of potions and lotions to meet you precise lifestyle and budget. My autistic obsession is your gain. It’s so much for me for and your skin will look amazing.

Categories
Biohacking Medical

Day 1754 and Do You Want To See Something Gross?

My inner child finds the idea asking if “you want to see something gross” to be funny. Of course, I want to see.

Gore and violence don’t get this reaction from me. I dislike it in movies and in the real world. But to see gross and the weird in the real world. I get it. Maybe lots of humans thinks seeing gross things are cool.

I think it is a bit sweet. It is as a very human reaction go “ewww cool” when faced with non lethal wounds. Maybe it’s truer with boys than girls, but if a kid said “do you want to see something gross?!” in Colorado when I was a tween the answer was a rousing yaah! Gross things are cool.

Maybe it’s a type of survival mechanisms where if we can learn more about what is lethal, and lethal injuries look like, it then improves our Darwinian fitness. We judge risk more accurately.

Flesh wounds need proper care and do turn out absolutely fine. And boy have we improved on the science of wound care since I was a kid. We have evolved past the bandaid.

When I first did my wilderness incident first responder training, I went worried I’d find the injuries we’d be treating emotionally challenging.

But even in a hard situation like a fire burn or the dermis getting sliced open, I still had a bit of that bravery of a little girl. That is cool! The bravado of a human who believes we can fix it

If you enjoy a story of plucky Rocky Mountain woman learning to do emergency care for herself and her community I’m glad we shared this time together.

Hopefully you never need these emergency skills. We take learn the risks and practice for them so we may never experience them.

So if you don’t feel this way, I’m giving you your ticket out of here. Stop reading now. But if you want to see something gross stay on.

For those who who are like “actually I want to hear all about getting your left butt cheek sliced open” to raise and normalize your testosterone levels by injecting tiny pellets of hormones though a steel dart gun via the scalpel entry point. Then it’s time to see something gross.

This is my wound on Wednesday morning after I had the procedure. It’s much bigger a slice than I’d expected but first time practitioners (I asked for the experiment) and while the treatment is safe across most vectors, I was a nervous immune compromised patient who prepared for the worse.

So this a real 10/10 “let’s see how it goes from here” experiment especially if the returns it delivers are real. I hope for the energy, pain tolerance and healing benefits the average patient sees

Now I am lucky enough to be an owner and finally user of my very own hyperbaric chamber for oxygen therapy. I wrote about it at length through trade wars and trips to Istanbul. We finally got the OxyRevo from China last month. I intend to upgrade to an HPOTech in our finished medical space (I believe HPOTech the best on the market currently)

So I am using a 90 minute full 2 atmosphere protocol already as I go went this treatment. I had also begun testing the GLOW stack from a peptide spot where I trust the owner. I’m helping him test. And this is the recommended stack for recovery.

.01 of the GLOW stack which is a regenerative peptide therapy with three peptides—BPC‑157, TB‑500, and GHK‑Cu—it was made to promote healing, tissue regeneration, and collagen production,

So I am absolutely throwing the gold care package at this. I am taking collagen and biotin, we’ve got the local food and the lack of seed oils, we’ve got the best current standard for peptides on injury and surgical recovery.

And somehow I am still scared. I never heal well or easily. I bruise easily and badly. I was so slow this summer to heal from an abscess surgery. I took a risk and I worried.

But I woke up this morning and my open wound has closed and the bruising has retreated in just five days to this. I’ll be in the scar mitigation territory in no time, and soon it won’t even be visible to the naked eye.

Day 5 of recovery from testosterone pellets

Progressively, the wound has moved from acute bruising and erythema toward decreased inflammation and resorption of bruising, with steady wound closure. Monitoring should continue, but the pattern suggests healthy tissue repair

So I hope you enjoyed seeing something gross. As it is keeping less and less gross by the minute.

Categories
Aesthetics Biohacking

Day 1752 and Too Much Protestant Work Ethic

I am pouring far too much autistic enthusiasm into my pet beauty shopping column that has a roughly half and half ration “theory of appearance culture in Protestantism” and half “specific routines at different price points” but I am enjoying it.

The heavier lift is going to be the work I am putting into the individual routines for the founding subscribers who have paid good money for help and I intend to give them my absolute all. I admit I’ve put way more thought than is probably necessary into each one but it’s a joy to track down specific products and geographic needs. It’s a shame that market editor was never a well paid enough job at a fashion magazine as I am pretty good at it.

Like, of course, I have opinions on the German drugstore market and its cost effective actives lines versus the old school naturals brands and where to acquire them. I don’t have quite as extensive a sample library of the market staples on hand but you know I spent hours browsing the grocery and retail shops when I was living in Frankfurt.

And on that note I’m going to bed early as I’m healing from my various biohacking experiments and I’m exhausted even with all the effort I’m putting into wound healing it still takes a certain about of rest to actually knit things together no matter how much time I spend with HBOT or what peptide stack I’m taking (it’s a spicy boy on the way in I’ll say that much).

Categories
Aesthetics Medical

Day 1751 and On Brand with Protestant Renunciations and Wound Care

I really misjudged my healing time on the testosterone pellets even though I pretty much always assume a worst case scenario for myself. I’m not really hurting but I am pretty bruised which is typical for me.

We may have some room for improvement technique with it so I am encouraged if the is as bad as it gets. I am not seeing any benefits from it yet and ugly bruising and a bit of an opening on an incision isn’t so bad.

A lot will depend on how well I recover and how much the hormone actually helps when I’m not healing. I’m also in the luteal horrors phase where my hormones are most ridiculous so I’m curious to see the curve.

The best part of this remains that I have a world class treatment for skin wounds on hand. Hyperbaric chamber oxygen therapy’s best research has been in wound management from burns to slow healing diabetics. So if I have to nurse a wound doing it with oxygen at pressure is actually pretty baller.

And to make it even more on theme, I spent most of my time in there writing out a column on skincare and the Great Male Renunciation of Appearances as part of my beauty shopping column and excuse to write about the secret history of appearance and its power.

Categories
Biohacking

Day 1748 and Putting Testosterone Pellets In My Butt Cheek

Intrepid biohacker that I am, when I learned that my testosterone levels were concerningly low, I began on a program to raise them.

I started with nutrition and supplementation but I already had a diet and supplement routine that was evidence based for raising testosterone levels in women.

I added in DHEA (Dehydroepiandrosterone) at 25mg. Six months of that brought me up to just about half of the lowest baseline acceptable. I was NOT getting adequate results.

My physician prescribed me a cream from a compound pharmacy which unfortunately didn’t agree with my skin. So we were going to get creative.

I had read a blog post from Cate Hall (whose husband Sasha Chapin had helped me on another entirely different vector of my life) on how testosterone pellets changed her life.

She had had teeny tiny testosterone pellets placed into her subcutaneous fat and had remarkable results in terms of energy and focus. This and that happened, and the summer was a mess, but today was the day I finally followed in her footsteps.

Vials of compounded testosterone

We’re started me with 10mg of estradiol (range 6-25mg with 8-10mg being most common), and 75mg of testosterone (range 50-150mg with the most common being 75-100).

We’ll aim for labs at 4-6 weeks after insertion which would represent peak levels. We will repeat dosing at 3-6 month intervals. We will check levels at 4 months or so, or earlier if I feel the effects waning.

Do be warned that within a paragraph or so, there will be images of needles, scalpels, and some blood. So feel free to not scroll down further.

Part of the difficulty with dosing this stuff is that the pellet doses are wonky and frequently out of stock – estradiol comes in 6mg and 10mg increments so 8mg is impossible.

Naturally, we’ve made surprisingly little progress when it comes to women’s health, particularly as it relates to hormones.

Prepared and ready to go

But as I am happy to be a guinea pig and my luteal phase is a mess of migraines and misery I figured I had little to lose and much to gain. I was the first patient my doctor has done the procedure on so if anyone in Bozeman is interested, you can confidently give it a go with him as I’ve survived it.

These cool tubes don’t actually go inside too far but sort of shoot the pellet into the incisions

I was given a local numbing agent with epinephrine. I needed a surprising amount of it but I was a bit nervous. Once I was just able to feel pressure and no pain it was time to make a small incision with a scalpel and in popped the tiny bit of hormone on the left butt cheek.

No big deal at all.

But if you don’t want to see it going in don’t scroll.

Just giving you space to turn back.

A tiny incision in my goose bumped bum with the little pellets easily tucked in

I am all bandaged up and still riding the cortisone of it all but I feel alright. I’ll be adding in progesterone orally to temper the estrogen as that’s another matter. I’m excited to report back on it as if I have even a fraction of Cate’s experience with it I’ll be quite happy. Also it’s about $70 a month so not cheap but not at all expensive for something that could potentially mitigate some long term issues I’ve struggled with for years.

Categories
Emotional Work

Day 1740 and Jungian Archetypal Stories

I woke up resolved to apply fresh energy to the new beginning that has forced me into a cycle of grief as I memorialized my father and worked through his death. It’s been a strange and very sad month.

Jungian archetypal stories such as the symbolically significant “kill your father” narrative are templates and fundamental patterns that appear in dreams, literature and myth.

These stories come from the 12 archetypes of Carl Jung and are meant to show fundamental drives and lessons that repeat across human nature. This chart Perplexity found me illustrates them nicely.

My generation’s parents have been alive, in charge, and looming large well beyond what many expected in traditional generational studies.

The fourth turning has nevertheless begun and scramble to secure position, authority and resources pits the remaining elders against their children.

Clearly this is not optimal and we should find our own Jungian stories to free us to reach our own future without the literal end of our fathers. But if one has to suffer this loss then I’ll make the best of it.

Categories
Emotional Work

Day 1739 and Inflammatory Grief

I am giving myself till the end of the day to feel the anger, pain and frustration that has come to define the grieving process I am in. I lost my father quite recently and it has been an awful experience.

After the memorial ends at 5pm today I intend to let go of what I can even though I know I don’t have full control over it. I had little to do with it at all.

From the moment I learned of his passing I knew it would be a challenge due to the complicated family circumstance.

I’d been preparing for this transition for some years, both for health reasons and because I know that not being next of kin means I have little say in the matter. My time with my father was from a different era of his life and I am grateful for what it gave me. I love my father and always will.

I won’t lie about how much this experience has hurt. I was able to handle a few emotional body blows as I know my father and I have forgiven him a thousand times over for any pain and trauma as it got me here.

That my father struggled to forgive himself seemed a given to me and I intended to extend whatever grace was necessary to those who carried him through his final years.

Everyone experiences grief differently and strange flavors of hostility have indeed surprised me. Sending a living woman’s private erotica kept by her former husband to her daughter is a special kind of fucked up.

In grief, whatever one has to do to the villains you have built in your head is alright by me. It hurt but I don’t think I am hurting as much as someone who would do this. I am doing what I can to not become inflamed by it. These choices are what was deemed necessary.

I do however think we are unprepared for the many private painful emotional moments that will come with the fourth turning as baby boomers pass and their children across modern families grapple with what was broken and its costs.

I consider myself to be incredibly lucky in this regard as I knew it was coming. I am less sure we are prepared as a civilization for the pain that will arrive as more change and death arrives.

Categories
Emotional Work

Day 1738 and On The Far Side

It’s been a weird week. I’ve kept a slight distance to the logistic of it for sanity, but my father’s memorial is being held tomorrow. He passed over the last long weekend of summer. I found out by voice mail.

It is a complex family dynamic and I am not (insofar as I can tell) invited to event. I know it sounds odd to be unsure, but given how the information has flowed, who has been prioritized, and the reactions to condolence communication I’ve done my best to keep a respectful distance. My grief isn’t the most important grief.

Neither of my father’s children nor his previous wives will be in attendance. It’s not necessarily our choice, or even our place, to have an opinion as he had a third family who welcomed and loved him and I am grateful for their generosity. He had no further biological children but he had another family.

We’ve spent the last few weeks doing a comical amount of legwork with the help of kinds souls, friends and my mother to acquire the ideal floral arrangement and make sure it arrives alive and healthy.

Two Venus fly traps carefully placed in a cardboard box for travel from Colorado Springs to Boulder

In an age where Miss Manners would find few remaining social mores, a respectful but symbolic floral display seemed the most likely to be acceptable and held the most meaning for me and the father I remembered.

He loved Gary Larson, and in the early nineties convinced him, through a bouquet of carnivorous plants to participate in calendar application for Macintosh. Gary decided the Internet wasn’t for him later but that early desktop computer program and its genesis remains a favored family story. A creative and bizarre tale of making something happen.

The Far Side Computer Calendae

Alas it’s not all charming anecdotes. Yesterday a large box arrived with a return address in Big Fork Montana. That is where my father had retired so we knew it was likely from his estate. Part of our hopes in moving here was to be closer to family.

Inside was a mess of the broken glass, old picture frames and hundreds of photograph of a life that my mother, my half brother and my father lived quite happily for a time.

Hiking, fishing, skiing, my first golf lessons, and horse back riding photos filled out the details of a childhood between spectacular eighties family portraits.

Little evidence of the hard years of poverty in tiny apartments was included. It was entirely the glory years of boom times. They were happy memories.

There were also glamorous soft core pictures of my mother in lingerie or swimwear which my father had apparently taken himself. I was initially quite shocked.

Nigh professional grade photos of my mother posed like a pinup are not exactly what one expects in an estate dump of memories. Especially as she is very much alive and well.

My mother’s has given me permission to discuss the images, though she was a bit shocked to learn they still existed.

She swore she had them destroyed but I’m glad they were not as I enjoyed seeing her beauty and vitality. Everyone deserves to remember the years where they were at their physical peak.

My father was a man of many talents and interests and he loved to learn new skills on the latest gadgets. I just didn’t expect to learn he was that sort of artist.

I hope the flowers and our card will be accepted tomorrow. I’ve been reeling slightly from the photo dump and its unheralded arrival. It felt like one last piece of unkindness when magnanimity would have been simpler.

I don’t know if anyone will understand the story behind the flower, so we have made arrangements for the plant’s well being if they are not. It is an imposition to send a living thing and it was my hope to do as little imposing as possible that might cause distress.

My grief is my own. A whole life was in that box and I have no idea if anyone will remember or recall any of it as anyone who was there isn’t invited. But I remember and I will treasure it. He’s on the far side now and free of petty concerns. I love him and I always will.