Tag: Biohacking

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Biohacking Medical

Day 1890 and It Bears Repeating Or Does It?

I can’t say I have fully recovered from pushing myself to my operational limits to do work (which looks a lot like socializing in my line of work) while still recovering from an infection after dental work.

It’s always recovering from an infection these days. I’ve been on some kind of antibiotic or anti-fungal every day since October.

2025 for me was getting an infection and then recovering from an infection on repeat. Ever since I decided to swap my biological injection 15 months ago from Coesyntx to Bimzelx and I think I’ve hit my limit.

It’s just too damn depressing that it’s a constant threat that I’ll have either a soft tissue infection or an abscess or a swollen gland that turns into a staphylococcus colony.

It’s as if I’ve got no skin biome left which is almost certainly true. I think I’d rather have CRP and sed rates and risk other infections than be rotating antibiotic varietals like some kind of junky afraid to develop a dependency.

Except instead of pain pills or lady downers it’s amoxicillin versus doxycycline versus Cipro with the occasional dalliance with a macrolide. I’ve also come to appreciate the benefits of Fluconzole. It’s not great. If you want a quick AI generated overview scan along

  • Beta-lactams: This broad group includes penicillins (e.g., amoxicillin), cephalosporins (e.g., cephalexin), and carbapenems (e.g., meropenem). They work by inhibiting cell wall synthesis.
  • Macrolides: (e.g., azithromycin, erythromycin) These inhibit protein synthesis and are often used for respiratory infections.
  • Tetracyclines: (e.g., doxycycline) Used for a wide range of infections, they inhibit protein synthesis.
  • Fluoroquinolones: (e.g., ciprofloxacin, levofloxacin) Broad-spectrum antibiotics that inhibit DNA synthesis.

My problem is that going back to my old biologic will take three to four months to full dose and it’s not a risk free process. And my full biometric panel is better on Bimzelx so is it really so bad that my resting heart rate is in the upper nineties every other week?

I think it may be time for me to make a pilgrims to the remaining clinics and pretend that I have any remaining institutional trust. Maybe I can vibe code something usual along the way.

I intend to support others on this journey as I’ve been chronically this journey a long time and the times are changing as we bring more artificial intelligence to the inference issues around our biometrics.

Categories
Chronic Disease Startups

Day 1889 and Recovering from Normalcy

I had such a lovely day touching grass (and sand) yesterday. I slowly worked through a 36-48 hours of of talking, walking, strategizing and occasionally reapplying sunscreen (I still got burned a little on my shoulders) with a friend who is preparing for big life and company changes.

These are the activities of normal life that I cherish, but my body seems hardly able to manage the strain this week. Now perhaps these activities are stressful on the mind and soul, but should they really be so physiologically taxing for me?

My Whoop is showing high strain

Now yes I am recovering from some dental work and on antibiotics but shouldn’t I be able to have a calm day that most would consider restorative? The serene peace of sitting on sandy shores should surely outweigh any areas from consequential questions of power, compute, realism and human purpose right?

I have barely been able to get out of bed today and the ten minutes of squats and planks I did to test my capacity spiked my heart rate into the stratosphere.

Which is odd as I woke up with my RHR in the 60s which is much better than usual. I only get into the 60s or 70s consistently when I am on heavy antibiotics.

The two weeks I was on Cipro recovering from surgery this summer my RHR was in the mid sixties so clearly I’ve got something going on with low grade infections.

I struggled mightily to organize my thoughts enough to write even this post. I feel I might even have it in me to go for a walk. Which is encouraging as I missed the sunset. The sunsets are obviously an event when you have a beach or far off horizon to enjoy with then.

Categories
Biohacking Internet Culture Politics

Day 1886 and Whoop There It Is

Quite a weekend for Americans and the wider Persian Gulf. Let us hope it is resolved swiftly and with the least loss of life possible.

It happened quickly. On Friday night policy types were arguing about artificial intelligence with our department of war about use cases and contacts. And then on Saturday we bombed Iran and they bombed pretty much every neighbor they have. No wonder they had a midnight deadline eh?

I’ll stick to human interest here but Chief of Staff Susie Wiles appeared to be wearing a Whoop tracker in a secure room which was confirmed by the company’s CEO by tweet.

The original concern being that some fitness trackers break NSA protocols as they have audio recording and other data recording which wouldn’t be appropriate in a dark room type the situation room.

Interestingly Whoop is approved by the NSA for use in these situations. Per the CEO the Whoop does not include a microphone, GPS, or cellular capability of any kind and has long been on the NSA approved PED list.

I myself wear both an Apple Watch and a Whoop everywhere but I rarely need to be out of the prying ears of recoding devices but it’s good to know.

Whoop’s CEO joked that given the success of the mission Susie Wiles must have had a green recovery score (quality sleep, low resting heart rate and high HRV) though I imagine she must be feeling the stress now that it’s over.

I wonder if her score worse than mine. I needed steroids and antibiotics to manage the flare post dental work and my body is under more strain than you’d imagine.

It’s somehow nice to know that the most powerful people on the planet use the same tools as I do to track their biometrics. From billionaire founders like Bryan Johnson to the Chief of Staff of the President to little old me. We all wear the same track. If you want a referral code here you go.

Categories
Travel

Day 1874 and Delayed Jet Lag

When you travel as much as I do, you get pretty good at managing the logistics of it. It’s a common theme on the blog as I relish being competent at travel but I also have complicated emotional baggage about its necessity.

Still I would relish a competitive packing game. I think a game show akin to Supermarket Sweeps but with managing a multi-leg transcontinental commercial flight would be great television.

Alas the fun and games stop where your body begins. And your body is never quite as capable as you might wish. Being evolved for living by circadian rhythms means jet lag is just a gnarly feeling no matter the tactics you use to combat it.

Yesterday was taken up by a work victory lap which kept my cortisol pumping and my energy up. Today however I can feel the jet lag hitting like a brick. I’ve been trying all day to work up the energy for basic tasks and losing. Tomorrow is another day.

Good thing private taxis for burritos exist as I might have simply chosen to fast for lack of energy to make or even acquire food. Though fasting wouldn’t have been a bad way to spend this clustering of holidays. It’s Shrove Tuesday, Lunar New Year and Ramadan. Much of humanity will be in joy and prayer today so that out to help lift anyone’s spirits.

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Travel

Day 1870 and Cutting Down On Packing Time

I am a very thorough, well honed and time tested, and Karen hardened packing methodology.

I have a little bit of childhood anxiety around packing for having moved around a lot that has alas never left me. Many people having anxiety about flying so at least it is a bit relatable but I don’t know if packing anxiety is as common.

For me it’s not about being in the air but rather leaving behind an established base for parts unknown. Will I be able to find medicine for issue that arise or soap that won’t trigger eczema? What if I need to appear at an event requiring a dress & makeup? What if I need to walk for two miles with all those things?

Every time I pack I go through the same routine and I use the same bags with the same labeling system to manage all the permutations I might encounter. And it is a science.

I have a small pajama bag I carry in my backpack in case of an unexpected overnight or long delay. I carry small clear vanity case to clean & groom myself with full allergy protocols that passes even the crankiest Heathrow checkpoint. I am prepared.

I carry on my person a a small pill bag with every detail labeled that can handled medical incidents big and small along with my first responder certificate. If you have an issue on an airplane you want to be seated next to me.

From there in my carry on suitcase I label the packing cubes with every item I bring, from underwear to wrap dress and ballet flats. Everything that is packed in my larger Tumi that gets checked is also labeled and I place an itinerary on top as I find my bags opened more frequently than seems reasonable.

There are no questions from the TSA or the most belligerent customs agent that won’t be immediately cleared up with minor inspection. Now with artificial intelligence I can translate my labels on the fly into any language.

Despite this clarity and organization, I admit I’ve had a few amusing incidents. Once through Heathrow I unsettled a British Airways agent with my fiber and protein powder baggies. Because clearly middle aged woman would smuggle in a quart sized baggie of cocaine in her purse.

I really wish with all the travel I do and my very strict system that this would all somehow take a little bit less time than it does. I generally allow myself two days to pack as I like to check and double check as it’s an iron law that things will be forgotten. And Montana is remote enough that if I forget a fancy serum or a favored sweater I won’t get a replacement easily. We only just got a Sephora this year.

I am however headed for a large American city that has absolutely everything I could possibly want in short order. So as I leave behind a European home base where I do keep things on hand (I didn’t always but extended family has been kind to me) I feel much less pressure this time. And still somehow I will allow myself to let it take more time than I’d prefer.

Categories
Chronic Disease

Day 1863 and Head Above Water

Yesterday I wrote that I had no gas in the tank. Today is not much better. I am barely keeping my head above the proverbial water line. I finished a major purchase which I thought would give me respite for a few days.

Alas changes in destination, an emergency dental appointment for a family member, and the promise of rest was more like a promise of fretful semi-consciousness.

After days of rushing around seem to have swept me off my feet and into bed I still am not quite rested.

I thought I was mended yesterday but it seems as if I’m on the second day of exaggerated sleeping patterns with long arcs of sleep in the wrong places and times. Add in a bit of overheating on top of it and something feels off.

It’s not unusual for me to absorb major changes and shifts throughout their unfolding via some migraine induced osmotic pressure. I feel the animal spirits and global vibes push in past my physical limits and I shut down. I hope I’ll reboot soon.

Categories
Biohacking Medical Travel

Day 1856 and Always Something So Always Trying Something

The world is a topsy turvy place and I am doing my best to meet it head on. Physically I’ve managed a surprisingly steady period from December through January, even though I spent a decent portion of that on the road.

I credit this mostly to using antibiotic and anti-fungal regimens prophylactically. The biologic immune suppressant I currently take for my ankylosing spondylitis is quite frankly too good at its job. And I’ve tried quite a few.

That means I am locked in a battle of constant vigilance in order to keep my inflammation numbers down while also not becoming a host to bacterial, fungal or other infections. It’s a balance that is anything but delicate.

In 2025 I had been unable to fight off skin, soft tissue and mucosal infections seemingly at all. Even with extensive protocols for decolonization (intranasal mupirocin, chlorhexidine washes, environmental decontamination) I had four major infections.

Of those infections, three required surgery and the fourth was the result of a very minor incision to insert testosterone and estradiol pellets. Those surgical interventions proved very trying and also very expensive.

The last one (testosterone) helped quite a bit with energy but being energetic doesn’t matter much if you can’t fight off infections.

So while I know there is an individual and social long‑term systemic risk in using antibiotic prophylaxis, I will say it does seem to be helpful in mediating say outbursts of allergens flaring into soft tissue infections from skin breakage or having exposure to molds and fungal growths that fester in old damp buildings and water systems creep their way into any opening available.

Since it is always something, I figure I need to always be trying something. Frankly I am over the push and pull of managing medical care in America. It’s a mess and mostly designed at risk mitigation for the health systems.

I have found going abroad to be much more useful and cost effective in many cases. I may even find that it would be useful to document the experience in a format beyond a blog as I doubt I’m the only person manage complex chronic disease.

Categories
Travel

Day 1847 and Cardio versus Packing versus Ski Bunnies

I’ll be on the road for a portion of tomorrow. Other members of my traveling party have already pulled ahead to parts unknown, as shifting obligations and vehicle needs turned schedules this way and that. Nomads as we adapt to a new world.

Europe is in a tense state and the weather hasn’t helped much. As I’m writing, Davos is awaiting Trump speech in the Swiss mountain town.

I finished a workout in the hotel gym but my room wasn’t quite ready for me, so I went down to the lounge to take in the BBC having had my fill of Bloomberg commentary while in the gym.

Management must keep up with their bosses

You can probably spot the hotel brand and imagine easily my experience intaking the World Economic Forum by proxy as I attempt to manage my life and health in the unspooling of the order of things.

I packed up a slightly unusual range of things for my transit tomorrow, as I had been going by car but will hop a low cost carrier to recenter. Somehow this has my large luggage separated from me. I’m carrying a very fine leather duffle I recently acquired as a gift for my husband.

Will this work for my carry on and personal item?

I have gone from doing a bit of cardio bunny as I work to improve my V02 max to a pack rabbit, as I moved around this and that to be sure my cascade of items and medications were within reach and packed appropriately. And would make weight but I’ll get to it.

I’ll not end my travels as a snow bunny in Davos though I have seen rather a lot of snow in Southern Europe as far south as Greece.

Why are bunnies on my mind? Well I have to keep in mind some odd weights for the low cost carrier I’ll be using for a short hop. Just look at this guide to baggage.

3kg is a silly amount of weight for a bag. That’s the weight of a house pet like a bunmy

3kg (3 kilograms) is equivalent to approximately 6.6 pounds. While this weight is roughly the size of a medium-to-large house rabbit rather than a “small” one, it is a common weight for many everyday household items like a large bag of flour or three liters of milk. Via Perplexity and Weight of Stuff

For whatever odd reason, the carrier listed your personal item or under seat bag as needing to weigh 3kg. This is about the weight of a house rabbit.

Which is honestly not a lot. I doubt any purse I’ve ever carried is under 3kg when you account for laptop, shoes, cosmetics, wallet and other sundries. But we shall see if my backpack can do it. Nothing but pajamas and medications ought to keep it light.

Categories
Biohacking Medical Travel

Day 1846 and Doctor’s Orders

I have had a lot of experience with doctors over the last few years. A chronic autoimmune condition isn’t the sort of illness that gets “better” like a virus. It can only be managed.

I have come up with endless ways of collaborating with people who far too often believe they are more informed, powerful and intelligent than me.

Sometimes they are even right about that perception. It’s a frustrating fact of life that doctors value their status occasionally more than their patients.

Today I went to a tourist hospital renowned for its extensive offerings and professionalism. My usual interpreter (it’s in a foreign country as many nations from Mexico to Turkey to South Korea serve American patients) had a number of procedures and visits organized for me. I felt confident I’d learn a lot and maybe find new pathways to healthcare management.

I happened to have an aesthetic elective treatment first. A plastic surgeon met with me to refresh some Botox. That seemed excessive given a nurse does my light work back in Montana but why not get a professional opinion while you have the chance.

I’d intended to spend the afternoon at the hospital doing a number of more productive activities than smoothing my fine lines. I’d set up rheumatology and immunology lines of questioning and I was excited to get some holistic work done including ozone and an IV infusion of vitamins and minerals.

Alas I was stopped in my tracks by a physician who simply would not approve the IV I had set up, the ozone work, nor would she approve the alternatives I suggested (an intramuscular B vitamin shot). I made my case with the interpreter and my AI.

The doctor wouldn’t budge. She even obfuscated suggesting that glutathione was illegal though backed down when it turned out to be a malpractice issue related to compounding pharmacies.

I very much wanted to buff up my immune system, especially having chosen something elective to go first, and I could not make progress. It shut down my whole afternoon. All that was left was tests and waiting.

There was no order the doctor was willing to give for short term immune improvements unless I committed to five weeks of procedures which given it was a tourist hospital seemed a little ironic.

I am demoralized but doctors will be doctors. I never seem to manage to convince them when I really need it. Doctor’s orders are not always for the benefit of the patient. Maybe no one wanted a woman sitting around hooked up to a vitamin infusion. Who knows. I probably would have skipped the Botox though.

Categories
Aesthetics Biohacking Travel

Day 1845 and Lake Effects

I feel a ray of optimism emerging like a bulb who mistimes a false spring in late winter. I am in the dead of winter and I have the first glimmers of light.

“How you do one thing is how you do everything” is an aphorism about character that would take a natural born contrarian to engage.

I made a series of small decisions to keep myself still and make use of resources and skill clusters so I didn’t have to stress myself for a timeline that I didn’t make.

I took a few days to back off into medical tourism and longevity experiments. Nothing fancy or even novel. I wanted good sleep and a classic NAD+, Myers Cocktail, essential trace minerala, glutathione, Alpha-lipoic acid. Just good clean anti-inflammatory fun.

I want the good decisions about sleep habits and nutritional choices (sea bass, shaved vegetable salad, prawns and artichokes), the good exercise decisions (mobility and V02 max if I can’t push muscle too hard without impacting my my nervous system’s vagal tone).

I feel so lucky that this is a choice I can make. I need to be in fighting shape or the compounding choices of my health will have the wrong trend line. I want to see our future.

I am breathing slowly and watching a kind of lake effect whip up the water in the pool outside giving a fluid dynamics show to anyone who loves the movement of water and wind. That makes me want to live in our present.