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Biohacking Chronic Disease

Day 1433 and Pardon The Interruption

I’ve been running around keeping a busy schedule while I’m on the road for a few weeks on the west coast.

I had a number of things I wanted to do today but I’m so tuckered out I have been slowly passing on everything.

My stomach is upset, I’ve got a migraine that isn’t quitting and everything hurts. So pardon me for the interruption in my regularly scheduled posting but I am going to attempt one of those sixteen hours of sleep nights in the hope that any issues can be fixed with rest.

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Emotional Work

Day 1423 and Reading The Riot Act

One of my friends recently fed the entirety of my daily writing experiment into Google’s NotebookLM podcast generator.

We both like to tinker with new artificial intelligence features and I have got a large training set with lots of tagging.

The synopsis it kicked out of two chatting AI hosts makes it sound like I have written a New York Times bestseller on the cultural and emotional adaption in the Great Weirdening.

The smoothing function of compression makes me sound way smarter than I think my daily output might suggest. The aggregate quantity has a quality all its own.

So naturally instead of sharing those wins with you I’ll show the emotional underbelly. He asked it to generate my blind spots and boy did the AI read me the riot act.

Beware the AI knows you better than you know yourself

I don’t know if I am blind to these as I see them as faults. I can easily go down rabbit holes and overextend myself. I worry about my physical capacity constantly. That’s why it’s such a clear theme in my writing.

I definitely recommend this as an exercise if you have enough personal content to feed into the generator. Seeing clearly into your blind spots gives you a chance see around the corners of your own life. It’s not quite the same thing as therapy but maybe just as useful.

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Emotional Work

Day 1414 and Signs

I’ve been a bit Delphic in tone over the last week. I’m relieved but also distracting myself with shopping, reading and health projects.

My natural optimism is looking for the positive. If you go in for numerology 14 is a good number for the moment as 1 represents independence, leadership and change while 4 is stability and balance.

The world is shifting but my path is clear in front of me. We may be on a chaotic course but the adaption brings us new opportunities. I’ll just do my best to get enough sleep when things get exciting

Categories
Emotional Work Politics

Day 1412 and Re-Centering

I am going to keep today short as it’s been an interesting week for everyone in America and I’m trying to get my body and mind right.

I was running a fever which seemed appropriate as the markets ran. We’ve been running experiments with red lights. I wish I had data to present (the setup may help others) but perhaps I need some better sleep to compound a bit before seeing improvements.

The relief I felt at the election being settled decisively has turned into a hard knot of unprocessed emotions about the way forward m. Maybe more of us will learn that liberal guilt isn’t terribly useful to anyone but it’s hard to hear lamentations when there is nothing you can do to help.

Many of the decisions we made as a family over the last four years are being rewarded. The revealed preferences we telegraphed loudly now show our commitment to running ahead of consensus.

I don’t just feel as if we are on the mark with our peers. I feel as if we are running ahead and have the freedom and space like never before. I won’t let myself be knocked off balance by life happening. We’ve been compounding our plans for years.

Categories
Biohacking

Day 1409 and Setting Up Red Light Home Automation for Better Sleep

I struggle with some chronic illnesses so biohacking is a hobby. Recently multiple friends have been discussing the benefits of using red lights at night to improve sleep quality.

There is some evidence blue light from screens decreases melatonin production which is why so many sleep hygiene guides suggest using a program like Flux on your screened devices.

Running red light for 2-3 hours before bedtime may help lower cortisol levels and increase melatonin production. Plus it gives your bedroom a fun boudoir vibe so we thought why not try it?

Philips Hue 60W Bulbs

We bought a set of Philip Hue bulbs for the three lamps in our bedroom. They sell their own automation systems to manage your thoughts but we already use Home Assistant from the Open Home Foundation for automation because it allows us to run basically everything entirely locally with no cloud dependence or internet access.

For our existing lighting we use a combo of Lutron Caseta (for built in lighting) and Philips Hue bulbs (for plug in lamps). For the purposes of the red light experiment in the bedroom, we are using all plug in lamps.

For the Hue bulbs, instead of using the Hue Bridge and the Hue App, we use the built in Zigbee radios to pair directly to Home Assistant.

Phillips should be commended for using open protocols and enabling users to use these non-proprietary standards. Interoperability is good.

To achieve the light color changes we wanted, there is a plugin called “adaptive lighting” that automatically color and brightness shifts the bulbs through the day (subject to plenty of configuration options).

In our case, Alex set them to go very red (1000K) while also limiting the sunrise to no later than 6am and the sunset locked to 630p in order to fit into our routine and preferred bed timings.

iPhones have an automatic white balance on their cameras but it is actually quite red at night

The lights mostly work automatically but for when manually control is wanted, there are Zigbee remotes on each side of the bed as well as Home Assistant bridged to Apple HomeKit so everything can be controlled via the Apple Home app or through Siri.

It may sound complicated but there are plenty of tutorials in the open source community to help guide you. As we get more data from our own biometric tracking I’ll be sure to discuss it here and on Twitter.

Categories
Biohacking

Day 1401 and Detox

I’m sure many a doctoral thesis has been written on the obsession with bodily purity and eternal search to rid oneself of toxins.

I’m not an academic but I was on the original Goop team in the far distant past when I worked for legendary adman Peter Arnell. So I’ve had a lot of exposure to particular purity culture that is modern consumer culture detoxing.

While I had hippie experiences with detoxification and also real ones like mercury chelation (which is a fun story), nothing is as intense as rich white women detoxing. From herbals to enemas to fasts you have a lot of choice.

I am all for the woo woo. The aspiration that if one just exercised enough control over oneself that all ailments could be cured is alluring. It’s also fucked up. Bodies are notoriously difficult to control and medicine is littered with mysterious ailments afflicting saints and sinners.

Alas I’m still tempted by this philosophy. I spent four days in Miami and I feel like a bunch of expensive detoxification treatments would be just the ticket. I’ll probably just sleep it off though.

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Travel

Day 1395 and Not On The Calendar

I am aching from doing too much packing in one day. Somehow a flight didn’t make it into my calendar and I thought I was flying Monday and not Sunday.

I usually take multiple days to pack things not because I’m unsure of my choices or dawdle over it but because the bending and picking up of things is hard on my spine.

I try to do these kinds of activities in 15-20 minute increments with an hour or more of laying down flat to recover.

Presume that packing for women requires extra effort when there is formal wear and cosmetics involved and I need a few hours to dedicate to the effort.

Chop it up into increments and well you can see how it becomes a thing I need to split up over a few days. I don’t think of myself as disabled but requiring breaks to rest my spine probably suggests it.

Alas the work and rest cycle wasn’t possible today as I had to get it all done in one go as my flight is at dawn. I am sure I’ll pay for the strain tomorrow. Which isn’t ideal for flying which is stressful enough without additional pain.

Thankfully it’s done. Now that this is all squared away I am in bed at 6pm and planning to go to sleep as soon as I can dampen the pain. Since I’ve got to be up at 5am a nice long sleep from 7pm seems perfect. And I’ll be adjusted to my new time zone.

Categories
Aesthetics Homesteading

Day 1389 and Fall Circadian Centering

I’m so happy to be home in Montana. While winter is my favorite season here, the Rockies have such beautiful sun filled falls.

Being a bit further north means we have such long days in the summer that our sunny summers can actually be a little too much. I

Perhaps ’m in the minority in this view but daylight till 11pm does make for a bit of midsommer madness.

But in October we are past the fall equinox. Our days are getting shorter. You appreciate sunrises more when sunsets are early enough for you to get a full night of sleep. Night having an edge on day means you appreciate the beauty of the light when you have it.

Sunshine on my windows, makes me happy like I should be.

The temporal pressures aren’t all gratitude journal bliss. There are a host of chores to be done before the first snowfall. We’ve been lucky this year it’s so late but temperatures should be below freezing soon. Alex and a few buddies redid the chicken coop’s roofing this morning. Keeping the hens warm and dry.

A new roof on the coop
Categories
Emotional Work Travel

Day 1385 and Adrenaline

It’s lovely to have the occasional day where you are running on adrenaline. I myself am not a big fan of stress as I don’t see it as a “good” in and of itself so much as a tool to be used to accomplish certain ends.

To that end, I live a mostly quiet life. I love being far off the map in Montana precisely because a routine with its habits allows me to take certain kinds of risks (particularly as an investor) in the wider world. A calm life lets me find early stage investing to be exciting rather than anxiety inducing.

It’s no coincidence that while I called my fund chaotic I prioritized calm in my own life. Why go looking for trouble when your professional life is all about the edge?

But sometimes it’s nice to experience the visceral risks of life. I’m in New York City and running from event to event and meeting to meeting. It’s all smiles and adrenaline and enjoyment for me. I’ll go home to Montana soon enough to my calm life. A little bit of chaos is a treat.

Categories
Biohacking Medical

Day 1375 and Titration

My joyful excitement over finally wearing a bathing suit I’d never worn? The peaceful swim in the salty sea ended in disaster within just a few days.

On Friday the allergic and autoimmune symptoms were so bad I took 5mg prednisone. On Saturday they were no better and I upped the dose by 2.5mg to 7.5mg. I moved forward my absurdly expensive biologic injection by a day. I haven’t been able to convince my health insurance to get them more frequently so it’s a risk.

I’m doing better today. My pain is abated to an almost unnoticeable level at a 2. That’s rare for me. And it makes me want to rush into as much work, chores and activity as possible just to enjoy it.

I’m typically working with a 5-6 level of pain on any given day but I can work (with medication) up to a 7 within reason. Past 8 I’m in bed and struggling.

The downside is of course that prednisone just sucks. It messes up your appetite. You balloon up almost instantly with side effects like moon face. And your body develops a dependency quite rapidly.

Titration off of steroids like prednisone require a steady and slow discipline so you don’t get “blow back” as it can make your symptoms even worse.

I’ll have titration for a few days ahead of me. But maybe I’ll get to enjoy the lack of pain. Already I’ve cleaned for an hour, done laundry, checked off a number of small “to do” list items and I am blessedly free of the exhaustion that comes from working with moderate to severe pain that is my normal daily experience.

I was sent a study in the journal Nature about a team who used CAR T therapies to achieve total remission in 3 patients. And I see hope on the horizon.

One woman and two men with severe autoimmune conditions have gone into remission after being treated with bioengineered and CRISPR-modified immune cells1. The three individuals from China are the first people with autoimmune disorders to be treated with engineered immune cells created from donor cells, rather than ones collected from their own bodies. Nature