Tag: Addiction

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Biohacking Medical

Day 1290 and Covid Experiment

I caught a case of Covid at the very end of May that took me down hard. I’d been struggling with “long” symptoms

So I tried an experiment. A pretty crazy one at that suggested by my osteopath and supervised by a doctor.

I am using going to use a 7mg slow release nicotine patch (of the type made for smoking cessation) for the next 3-5 days to see if it impacts my over-stayed their welcome Covid symptoms. I started my experiment at 9am Saturday July 6th

Day 1283 Nicotinic acetylcholine receptors (nAChRs)

The principle was pretty simple but not proven yet in clinical trials.

Nicotinic acetylcholine receptors (nAChRs) have been proposed as potential therapeutic targets for COVID-19. Research suggests that the SARS-CoV-2 spike protein may interact with nAChRs, potentially influencing the disease’s pathophysiology[1].

Nicotine and other nAChR agonists could modulate inflammation and the immune response, offering therapeutic benefits

Please do go read the original post with lots of caveats as nicotine is an addictive substance and this is not something to try without consulting your doctor.

I was unable to do the full 7mg but cut the patches down to 3.5 to 5mg over the five days. The side effects included headaches for the first day or so and a persistent queasiness.

Within a day I was lifted out of my exhaustion (which you’d expect from something modestly stimulative even though it was a low slow release dose). By the end of the second day my persistent coughing lifted entirely. I’d been struggling with congestion and coughing after even modest exertion like a walk outside.

I was functional on the fourth and fifth day like I hadn’t been since I got Covid. You can see me go into the red on my first day (my HRV dropped significantly but my RHR was only up by a few BPM). I slowly felt better and saw better recoveries even while taking on a little bit more exertion. I pushed a little too hard and found myself back in the red on my last day.

My Whoop recovery and strain chart for the five days of experiment beginning on the 6th and ending on the 11th of July

I was really relieved to stop the patch by the end. The last day of treatment I had overextended myself so I was in the red and feeling it even as the nicotine pushed my system up. I wanted to rip it off and did eventually cave at the end of the day instead of doing it all night.

My symptoms seem to be at bay. I feel decent enough so days after wrapping even as I began menstruation this morning. I hate to report that it also improved my usually debilitating PMS which typically includes intense migraines.

I would do it again if I got Covid. I cannot imagine ever using a nicotine patch consistently. I didn’t not enjoy the extra push of energy except insofar as it got me out of the exhaustion of the illness. I feel like it would be too much if I were otherwise feeling healthy. I have no cravings or side effects after.

Honestly I’m still wrapping my head around how well this worked. A part of me is confused, indignant and angry that a substance I was taught to fear has therapeutic benefit. Updating your mental models around long held beliefs is an uncomfortable process. But it’s a heck of a lot better than long covid symptoms.

Categories
Biohacking

Day 1284 and The Average Person

I am in the middle of a “don’t try this at home” biohacking experiment in which I am using a low dose nicotine patch to treat my week seven Covid malingering. A quick overview of the method of action.

Nicotinic acetylcholine receptors (nAChRs) have been proposed as potential therapeutic targets for COVID-19. Research suggests that the SARS-CoV-2 spike protein may interact with nAChRs, potentially influencing the disease’s pathophysiology.

nAChRs

I am doing alright with it. I was wary of keeping the patch on all night long (I am very sensitive to stimulants such that I won’t drink caffeine past 10am) so I removed it at about 5pm. That may have been a mistake.

Yesterday my Whoop recorded physiological stress. I wasn’t coughing, I had more capacity for exertion, and I felt generally less exhausted.

But I didn’t come down easily for sleep. I ended up taking a number of anti-inflammatory medications as well as an Ambien. My heart rate was stable but I felt “up” which I don’t care for at night.

And I did not wake up to good news. My HRV absolutely tanked. There are lots of confounding variables here in that I got good restorative sleep (medicine induced surely) but some strain has clearly been too much. 40% down isn’t a rousing endorsement.

I am also noticing a lot of chatter around addiction and whether or not it’s responsible to discuss these things. The fear that the average person is in fact prone so addiction and will have adverse affects. Which I’m sure is true. I don’t think normal people should take unnecessary risks and it’s good to have the minimum viable dose be none at all.

It’s wise to remember that I am not at all living in average circumstances nor do I have average medical conditions so I am not necessarily who you should be looking to for health advice. You should do the basics like eat more protein, lift heavy things, sleep an adequate amount, be in the sun and move around, and manage your baseline health metrics first.

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Politics Preparedness

Day 1276 and Not Just A River in Egypt

I’m pretty comfortable with being embarrassed. I get stuff wrong and I have to come to terms with it even as my ego complains bitterly. The ego protects itself with denial but that doesn’t mean its conclusions are correct.

Being impartial about your reality is hard. Denial is such a normal part of catastrophic events the CDC even has handy public health explainers. I hope post pandemic everyone can enjoy the irony of that.

Taking an impartial view when approaching a problem is hard. If it’s an especially destructive situation (as most forms of crisis tend to be) wanting to put off action is a common coping mechanism. We do it as individuals and we do it within the meta-organisms that form the cultural and political systems we live within.

My suspicion is that some of our current political problems are a result of denialism. Seeing things as they are is impossible for some people. Avoidance, rationalization and minimization is practically a skill set.

I’d hope in a crisis I would attempt to solve a problem with whatever meager tools and skills I had at my disposal. I’ve done my best to take action on a few slow moving problems. And yet impartiality only arises when I can accept reality. And I wouldn’t blame anyone who finding the reality completely unacceptable.

Categories
Aesthetics Emotional Work

Day 1237 and Having

“Having is not so pleasing a thing after all as wanting. It is not logical, but it is often true”

Spock “Time Amok” Star Trek The Original Series. 1967

Longing, yearning, pining, wishing…such is the romance of wanting . A simple verb “to want” has many beautiful words associated with its fantasies.

Perhaps this is why it’s helpful to remember that self improvement doesn’t work. We get something tangible from the fantasy of wanting. Our pop culture science fiction avatar alien humanity Mr Spock sees the illogic in wanting being more pleasing than having.

I recall being introduced by Sascha Chapin to Existential Kink as adjacent of this truism. We get pleasure out of resisting. The romance of wanting can give us too much joy to let go.

I enjoy the many spaces in my life where wanting has to is power. It gives me more space to enjoy having. I have so much right now. I feel it’s wealth every day in my life. The love of my husband. The safety in my family. The freedom of the position I occupy. The opportunities in front of me. I can yearn but it’s up against the power of having.

Categories
Biohacking Media

Day 1204 and Moral Panics

I do not care for podcasts but I listen to a Bloomberg podcast called Odd Lots for entertainment. I’m an avid participant in the niche in-group you might have once called Financial Twitter. The hosts of the podcast Joe and Tracy are part of this community as well.

Usually I listen to it for the fun expert guests who come to do commentary on their corner of the markets. Today’s episode was titled how the American workforce got hooked on adderall. Which I personally think is a very provocative title.

Over the last few years, users of the popular ADHD drug Adderall have been frustrated by regular shortages in getting their prescriptions filled. Various regulatory and supply chain factors have contributed to the inability of producers to keep up with demand. But this raises the question: why is there so much demand in the first place? How did a significant chunk of the labor force — from tech workers to Wall Streeters — begin using the drug as an aid for their work and everyday lives? On this episode of the podcast, we speak with Danielle Carr, an assistant professor at the Institute for Society and Genetics at UCLA, who studies the history of politics of neuroscience and psychology. We discuss the history of this medicine and related medicines, what it does for the people who take it, and how market forces opened the drug up to almost anyone.

Odd Lots “Hooked on Adderall”

My impression of Danielle Carr was of a nuanced thinker with a lot of historical insight who happened to have haplessly taken on some academic moralizing about whether the wrong class of person might be abusing stimulants. I’m perhaps the wrong class of person to be commenting as I don’t use any stimulants stronger than a cup of coffee in the morning.

I was struck how the narrative eventually came to demonizing market demands in contrast to the I’m sure completely neutral national health systems. The theory being we might keep better track of the vulnerable in such a system struck me as classist. Adderall may be an American healthcare market issue only because those poor London bankers have another go to black market stimulant. We just don’t mind because they make money.

Moral panics around pharmacological intervention seem to be a flavor of the decade sort of thing. Prohibitions catch on when the wrong kind of person gets themselves into trouble of abusing something that was otherwise contained to social sanctioned consumption.

Perhaps in less inclined to judge on these things because I don’t witness the abuse but I also think paternalism is the excuse schoolmarms and aristocrats love in equal measure.

Categories
Emotional Work

Day 1149 and Human Nature

I am experiencing a waning in my desire to be online. Not because I don’t wish to be in the thick of things, but because I simply don’t have as much I want to contribute when I am myself under stress. And it’s all stress now unless you simply stop caring. And I still care.

It’s human nature to be stressed at the available problems. I’ve got access to all kinds of problems now on my phone. So I am stressed.

I don’t have any reason to be participating in any stress but my own at the moment except that I see a lot of available problems because I am always watching.

I’d rather pay less attention. But paying attention is what pays the bills. Ted Goia says we’ve gone from art to commerce to attention to dopamine

An uncharitable view of people who sell art, commerce and informations or blame Athens, Jerusalem, Hollywood, and Silicon Valley if you must. In that order.

I suppose this view of information technology as unmitigated casinos of sin is true in a world of addicts. I don’t think we are all addicts. Nor do I think anyone who sells something addictive is a drug dealer.

I’m neither an addict nor a dealer but here I am selling and consuming information nevertheless. I’m not a Kardashian but I’m not a Buddha either. Maybe at best I’m Kim Kierkegaard. The sickness into death compels me to poast.

If we are all addicted to the constant influx of other people’s bullshit then I suppose the attention economy has moved to the addiction economy. We are addicted to the dramas of humanity and some of our dramas are more or less real than other.

A screen grab from a friend of the scariest thing in the world. An attention whore.

Except I don’t particularly want to be addicted to anyone’s bullshit right now. I’m not even all that interested in my own. I’m sick of my bullshit. Why should I pay attention to yours? At best I’ll pay attention to the bullshit on Netflix’s Love is Blind. I don’t mind if it’s packaged for sale. I actually prefer it. At least it wraps in an hour.

I’ve got a few basic principles that orient my life. I believe humans can make decisions for themselves. I believe most of us aren’t at all good at it because we are reactive impulsive animals with just the barest capacity for reasons.

But that capacity exists and it has separated us from the animals. We shall remained chained to the consequences of knowledge. I understand the impulse to blame that bitch Eve. But we’ve got the apple of the tree of knowledge so it’s time to accept paradise is lost.

Anyways, good luck surviving the churn and try not to fuck people over. Good faith is all we’ve got. Try to deliver value and not suck more resources than you deliver. Bow to the thermodynamic Gods and climb the Kardashev scale. Or keep up with the Cardassians. Are you sure you know how many lights there are? Better Google it to make sure.

Captain Picard getting Cardassian in the loop reinforcement learning. I mean torture. There are four lights.
Categories
Internet Culture

Day 1098 and We’re Back

I wish I hadn’t had insomnia last night as clearly ever came back to work today. It was electric in the hive minds of Twitter today. I am revisiting all kinds of priors as the timelines of different subcultures return back online.

I don’t know if anything I saw will stick but it’s clear that influencing public opinion is on everyone’s agenda. Elon Musk may have absolutely no zero intuition for how his narratives will play and maybe he doesn’t care.

I don’t think he means ill for what is still the only really unsupervised place for elite opinion influence and people are running wild with it. I’m almost sympathetic to Russian troll farms. It’s got to require enormous compute to keep on top of billions of malleable propaganda ready minds.

WhatsApp having trouble with “gm” tweets overloading the application has to be an urban legend but you can almost see it being true. Can you imagine every timeline across every cosmopolitan center pinging online and interacting with all the pieces of content that came before it? It’s a glorious perpetual process and I need to step off the wheel to rest. But I’m glad we are so back.

Categories
Aesthetics Internet Culture Media

Day 954 and Frame Jacking

It’s a war of all against all on the internet. And I don’t recall being conscripted into any kind of war but here I am up to my neck in ontological shock and crisis of meanings as I read the news.

Language is a virus. And we are all infected. I’ll let Ben Hunt of Epsilon Theory illustrate.

It’s our autonomy of mind that is threatened by this unholy troika of smartphones, social media and linguistic weaponization, and there is no more important struggle today than to defend ourselves against that threat.

Humans have nervous systems that are easily hijacked. You give us something to imitate and within a few weeks we’ve learned a new way to get a social advantage. And so we have massive social cataclysms as the rules change. And the rules are changing fast.

This TikTok about a woman accepting an engagement proposal because the vision of the future scares her? It might actually be an anti-natalist campaign by degrowthers or maybe even Chinese propaganda? Who knows.

It’s not as if America gives a shit about maternal health or women but hey here is a podcast about a porn star who specializes in anime’s less savory fetishes. Is your teenage boy an Andrew Tate fan? It’s time to enjoy a reactionary period.

Obviously this has anyone older than forty asking if the western world under attack. Is questioning liberalism actually the psy-op? Are we fighting amongst ourselves? Do you even know what memetic agents you are infected by?

I sure don’t what brain works in carrying but I don’t think animated porn is for me. But I also got taken in by lots of questionable narratives on modern medicine, fertility and children too. Untangling yourself from the desires you were given is exhausting. Good luck unpacking who jacked your frame!

Categories
Biohacking Politics

Day 952 and Do It Live

I found myself with a bit of anxiety this morning. I was afraid that I hadn’t done enough to promote some of my commitments this month.

This morning I co-hosted a session on nervous system work for founders and venture capitalists with Jonny Miller. Aside from a few Zoom hiccups, I think it well. But with my anxiety all I could think of is how I should have done more. I could have invited more more people, emailed more reminders, promoted it more on Twitter. Just more.

I don’t think my anxiety is about a Zoom seminar. It seems to be directed towards a bigger event next week. I am co-hosting a BBQ at my home for the Frontier Institute in Montana.

I am finding myself fearful that I’ve not not done enough to promote it. I’m afraid I’ll look like a fool and fail at my goal of raising awareness (and ultimately money) for our policy goals. It’s probably irrational but it’s sitting heavily on my emotions at the moment.

I care a great deal about the event being a success. And I have done quite a bit to promote it and invite the right mix of folks who will be interested.

I think even admitting to the anxiety helps me recognize that it’s irrational. I do think the BBQ will be a good time. We will have food, drinks, good company and if you’d like to come it’s on August 16th. Worth a drive into Gallatin I promise.

I wish I didn’t get anxiety about if I’m working hard enough to prepare for an event. The balance between preparing and promoting an event and having it go smoothly when it comes to performing live isn’t an easy one for me. I used to obsessively prepare for everything.

Which would then backfire on me as I’d use all my energy on the lead up and find myself exhausted and frazzled when it came time to be present in the moment for a big day.

So I’m trying to not get too much in my head about if I’ve done enough. What will be will be and I can trust myself to be present in the moment to succeed.

So if you are interested in joining the next Nervous System Mastery Bootcamp with Jonny Miller my code is JULIE and it will get you $250 off. I myself am an alumni of the course and plan to retake it again in the fall. So you’d be taking it with me.

And if you’d like to meet me in person August 16th and you happen to be in Montana I’d love to host you at my home. The topic of conversation will be the Montana Miracle and now we can continue to make the state a place for all to thrive.

Please join Alex Miller, Julie Fredrickson, and Padden Murphy as they host a meet and greet with Frontier Institute’s CEO, Kendall Cotton. We will discuss the recently passed YIMBY policies in Montana’s 2023 Legislative Session and the Frontier Institute’s future plans to ensure Montana is a place that all can thrive.

Come learn about the Frontier Institute’s impactful initiatives, enjoy some delicious food, and engage with a group of fellow Montanans dedicated to knocking down bureaucratic barriers and ensuring opportunity for all. 

Please RSVP to secure your place at this exclusive gathering. The address will be provided upon RSVP.

Categories
Media

Day 929 and Right Speak

My day has been a little off as I’m nursing my husband through some surgery. Through frankly he’s recovering so well it’s mostly just keeping him company while I do my regular workday. But I have consumed some good content in the process of keeping him company and making sure ice packs are rotated & medicine is taken.

I watched John Mulaney standup special Baby J which was surprisingly good. My main takeaway was “being liked is a cage” but also you’ve got to watch out for how selfish everyone is in the process of managing their own traumas and addictions.

Mulaney is a fascinating example of someone going from beloved to fuck up as soon as it was clear he was a human and capable of sinning and hurting himself and others.

He got a good dose of being condemned while being shitheel as an addict. Who he really hurt other than himself I can’t say. But he was problematic says many inches of gossip writing and critical reviews. Wrong speak and shame and condemnation is so interesting as a social engagement issue for culture. It’s never really about them. We can all be assholes and unlikable in the process of being hurt and healing our hurts.

I suppose this is why I believe it’s better to never take anything personally and be sure you take care of yourself if you find yourself reacting strongly to a person’s frailty. The ones who love you will forgive you if you need to reorient yourself into doing what’s right for you so long as you don’t hurt anyone in the process. And oftentimes even if you do.

The follow up movie we watched was also about wrong think. But instead of it being about the addiction and selfishness of a celebrity it was about the selfishness of trying to decide what’s right for an entire nation. We watched the Tetris movie.

Which is quite a dramatization of how totalizing even the most glorious of ambitions can be in the hands of hands of normal frail humans. Yes I think wrong think comedians and communists are related and I swear I still think Bari Weiss is kind of an asshole. Most of the comedians asking for forgiveness for wrong think aren’t actually that funny to begin with. Back to Tetris

I found myself inspired by the frustrations that come from human nature & self dealing while glorifying ambitious end goals for social good. The collective good can often be patently false if someone ambitious enough gets perverted. Maybe I’m just being that asshole capitalist but I think nepotism and corruption come in many forms. And it’s easier to spot it in British billionaires and communists bureaucracies. But we’ve got plenty of right speak and “for your own good” pleas right here in America.

It’s inspired me to look harder into how we are perversely seeking control and benefits for large corporations and political parties in our current race to regulate new technologies like crypto and artificial intelligence. If you want a hint as to where I’m worried look no further than Gary Gensler and reinforcement learning for artificial intelligence alignment. And yes I’m making bets to that effect.