Categories
Chronic Disease Medical

Day 1896 and Short but Sweet

The weather forecast for western Montana for the next several days is gusty high winds and five feet of snow in the high country so I suspect I’ll have some good down time simply because there’s a chance I won’t even be able to go outside.

I have a dentist’s appointment tomorrow morning, first thing, which I am a little nervous about as I’m not accustomed to having issues with my teeth.

The work I got done a week ago kicked up quite a bit of dust, if you will, and now I am struggling with a high heart rate and a very low heart rate variability. I can’t seem to improve upon the numbers.

If the dentist doesn’t spot anything wrong, then hopefully I can simply get a prescription for fluoride toothpaste and head to my family doctor as long as the weather holds.

I wish I had more to say but the energy I had budgeted for the day has been all used up. I’m not even confident I have the strength to focus on television with a plot line. It is a challenging prospect for me to stay upbeat when I get beaten down by my own body but it’s all I can do and I’ll have to accept it.

Categories
Chronic Disease Medical Politics

Day 1895 and If Not Us Then Who?

Despite persistent efforts to mitigate the downsides of my various medications, as well as maintaining dedicated wholistic lifestyle routines for my chronic diseases, I am not making adequate progress. I’d go so far as to say today it feels like I am sliding backwards.

But that is partially a function of luteal phase acute migraines and not the full picture on the ground. Yes, it’s true multiple metrics have gotten significantly worse over the 15-month span of my IL-17 inhibitor experiment with Bimselx and I am preparing to make the decision on what to do next. Many biometric markers are much better but the trade-offs are severe. It just feels like I can’t overcome them right now because I feel awful.

Nevertheless it’s important to remain grounded in the here and now. I think part of my trouble may be I am adjusting both to a new time zone and my normal altitude. Maybe I’m overly concerned by data points that will get smoothed out over time but it feels very spik.

Alas there is little room in life for downtime or bad days. Portfolio companies are fundraising, politics is getting uglier by the second, and one key blocker in my life has remained unsolved now for years.

I’ve never experienced a blocker quite so persistent as the American State Department’s handling of visa and immigration work. And yes that includes being disabled and chronically ill. That’s how bad state capacity is right now. My years-long attempt to get visas for family members to come help has not seen an iota of success.

But we keep going. There is much to be done, both practically and at higher levels of abstraction, and I am being whipsawed by hormone migraines over the last 48 hours. It is not an ideal time for weakness in one’s body.

Yesterday the best I could do in terms of writing was some rambling about my irritation with new retail sales cadences at Sephora feeling down market. Not that I necessarily need this space to be filled with decent content but I know that I am not running at even 10% capacity.

We all have to contribute our talents to this moment in time and there are projects that I wish to commit more time and energy to, even though it feels like it may be the death of me. But if not me then who? It’s a question we should all be asking ourselves and I hope more of us rise to the challenge.

Categories
Aesthetics Politics Travel

Day 1891 and So Much for Santorini or Status Hierarchies for Abundant Ages

If you watch me closely (which would be weird but I make it easy enough) you have surely noticed I spend much of my life traveling.

I’ve got no training in psychology but it sure seems like a certain personality type takes their childhood traumas and does exposure therapy till it becomes enjoyable.

I had intended for another trip to the general Mediterranean area in the spring to see family and work undisturbed by the American media timezone distractions. Now I am unsure if that will be feasible.

I am guessing that the sort of people who go to Sicily, Santorini and Cyprus to soak up the sun may find this Iranian conflict putting a wrench in their island hopping. Where will they go instead? Cartel wars bleed into the Caribbean and Bitcoin zillionaires setting up economic zones might make other things tricky. And oh the fuel costs will be ruinous.

War certainly makes me reconsider standard air bus style flying near any seas that connect to conflict areas but not too long ago I sat in a Turkish airport where “final boarding for Damascus” went over the loud speaker so maybe I’m making too much of it. Though I’m glad I enjoyed Istanbul over the winter as anything bordering Iran is now unnecessary risk.

For a world where speculative fiction bull case for artificial intelligence wiped off billions in market capitalization, we sure aren’t taking very seriously the kinetic effects of extreme uncertainty and change. Well, ironically maybe Pete Hegseth might be.

If we do make it through the Jackpot to the other side of the singularity, or just through this regional war situation, I would bet humans will find ourselves getting back to status hierarchies and power games.

If all our consumption needs are met, there will always be hierarchies. Wait your best friend summers in Block Island too? Or are those the Finnish slides from the Comme des Garçons show? Let me just call up “insert social scene’s patron billionaire” as everyone is headed to Big Sky for fresh powder this weekend.

It’s endlessly that sort of thing if you are inclined towards Bourdieu’s Distinction: a social critique of the judgment of taste. If class predicts taste then we mimic the taste we think we ought to have to be a certain kind of person. I came across a sweet hand illustrated essay on the matter recently.

If we can have anything we like, then taste becomes finer and finer grained. The rich know this already and the rest of us just might find out if we survive to an abundance era. And as I’d like to do that maybe I be reconsidering heading out to sea. Caribbean, Ionian, Bosphorus or otherwise.

Categories
Biohacking Medical

Day 1890 and It Bears Repeating Or Does It?

I can’t say I have fully recovered from pushing myself to my operational limits to do work (which looks a lot like socializing in my line of work) while still recovering from an infection after dental work.

It’s always recovering from an infection these days. I’ve been on some kind of antibiotic or anti-fungal every day since October.

2025 for me was getting an infection and then recovering from an infection on repeat. Ever since I decided to swap my biological injection 15 months ago from Coesyntx to Bimzelx and I think I’ve hit my limit.

It’s just too damn depressing that it’s a constant threat that I’ll have either a soft tissue infection or an abscess or a swollen gland that turns into a staphylococcus colony.

It’s as if I’ve got no skin biome left which is almost certainly true. I think I’d rather have CRP and sed rates and risk other infections than be rotating antibiotic varietals like some kind of junky afraid to develop a dependency.

Except instead of pain pills or lady downers it’s amoxicillin versus doxycycline versus Cipro with the occasional dalliance with a macrolide. I’ve also come to appreciate the benefits of Fluconzole. It’s not great. If you want a quick AI generated overview scan along

  • Beta-lactams: This broad group includes penicillins (e.g., amoxicillin), cephalosporins (e.g., cephalexin), and carbapenems (e.g., meropenem). They work by inhibiting cell wall synthesis.
  • Macrolides: (e.g., azithromycin, erythromycin) These inhibit protein synthesis and are often used for respiratory infections.
  • Tetracyclines: (e.g., doxycycline) Used for a wide range of infections, they inhibit protein synthesis.
  • Fluoroquinolones: (e.g., ciprofloxacin, levofloxacin) Broad-spectrum antibiotics that inhibit DNA synthesis.

My problem is that going back to my old biologic will take three to four months to full dose and it’s not a risk free process. And my full biometric panel is better on Bimzelx so is it really so bad that my resting heart rate is in the upper nineties every other week?

I think it may be time for me to make a pilgrims to the remaining clinics and pretend that I have any remaining institutional trust. Maybe I can vibe code something usual along the way.

I intend to support others on this journey as I’ve been chronically this journey a long time and the times are changing as we bring more artificial intelligence to the inference issues around our biometrics.

Categories
Chronic Disease Startups

Day 1889 and Recovering from Normalcy

I had such a lovely day touching grass (and sand) yesterday. I slowly worked through a 36-48 hours of of talking, walking, strategizing and occasionally reapplying sunscreen (I still got burned a little on my shoulders) with a friend who is preparing for big life and company changes.

These are the activities of normal life that I cherish, but my body seems hardly able to manage the strain this week. Now perhaps these activities are stressful on the mind and soul, but should they really be so physiologically taxing for me?

My Whoop is showing high strain

Now yes I am recovering from some dental work and on antibiotics but shouldn’t I be able to have a calm day that most would consider restorative? The serene peace of sitting on sandy shores should surely outweigh any areas from consequential questions of power, compute, realism and human purpose right?

I have barely been able to get out of bed today and the ten minutes of squats and planks I did to test my capacity spiked my heart rate into the stratosphere.

Which is odd as I woke up with my RHR in the 60s which is much better than usual. I only get into the 60s or 70s consistently when I am on heavy antibiotics.

The two weeks I was on Cipro recovering from surgery this summer my RHR was in the mid sixties so clearly I’ve got something going on with low grade infections.

I struggled mightily to organize my thoughts enough to write even this post. I feel I might even have it in me to go for a walk. Which is encouraging as I missed the sunset. The sunsets are obviously an event when you have a beach or far off horizon to enjoy with then.

Categories
Politics Preparedness Startups

Day 1887 and Trust Me Bro

I don’t feel terrific so I’ll keep this as a ramble but with some links. I fear some sort of Rubicon has was crossed, which we will only recognize in hindsight, in the fight for property rights in America versus the tyranny of failing state capacity.

I am referring to the contract dispute between foundation model developer Anthropic and American Secretary of War Hegseth that boiled over on Friday night as some sort of Murderbot surveillance subplot parsed only by lawyers, policy wonks and anyone who remembers the patriotism of Chelsea Manning.

Right before America and Israel went all Epic Fury on Iran over the weekend, somehow it was felt a messy public fight between defense contractor and the civilian oversight of our military was ok? Good thing everyone is too distracted to care.

Funny how one can go from cheering on our military’s capacity for innovation one week and the next to be waving one’s arms screaming “no oh no no no” but that’s just politics as run by the instincts of reality television I suppose.

The best writing on this so far has been Dean Ball (who worked in this Trump administration on its AI position statement not so long ago) who feels that Hegseth took an approach on renegotiating a contract with a frontier AI model developer that has consequences.

Loosely and I am missing much Anthropic had its previous contract to parse classified documents in the Department of Defense (now the Department of War) negotiated by the prior administration. Some aspects of this contract wasn’t going to work for the Trump administration. Anthropic didn’t want to change it and Hegseth threatened to call Anthropic a supply chain risk unless it complied. They didn’t and Sam Altman signed a deal.

Wrapped up in this is that of course we all eventually comply with Leviathan who has the monopoly on violence. I don’t claim any expertise here but lots of people understand defense contractor law.

On its face Anthropic looks like the moral high ground and the position all capitalists and private property respected would prefer. However, it’s in Dean’s words, a bit weird for a company to tell the state that a private corporation has a say in policy as opposed to our democratic institutions.

Anthropic is essentially using the contractual vehicle to impose what feel less like technical constraints and more like policy constraints on the military

This is all complicated by the model developer having wishes for frontier AI development to be nationalized and for their work in particular to be safeguarded by a different political administration. It has become a right versus left thing as it was bound to do.

Now Anthropic gets to enjoy the full throated defense of its industry peers and even conservative policy makers like Dean, because our current state capacity is not what I’d call excellent when it comes to our civilian government capacity. Honestly our military still seems to be crushing it.

Secretary Hegseth looked a bit like he was over reaching in his command that he get his demands met. Americans are very touchy about surveillance of if’s citizens and much less touchy about autonomous weapons so it’s natural to be a bit suspicious if you are a millennial who remembers the Global War on Terror. If you are Zoomer who doesn’t know who Chelsea Manning is please go ask Claude.

However it’s not at all clear that Hegseth’s original negotiations were out of hand as of course it’s the state who decides legal use not the private company and we are meant to have laws, judicial process and all the rest. It’s just that we don’t. So what on earth do we do about it? Trust me bro is not a policy.

Categories
Biohacking Internet Culture Politics

Day 1886 and Whoop There It Is

Quite a weekend for Americans and the wider Persian Gulf. Let us hope it is resolved swiftly and with the least loss of life possible.

It happened quickly. On Friday night policy types were arguing about artificial intelligence with our department of war about use cases and contacts. And then on Saturday we bombed Iran and they bombed pretty much every neighbor they have. No wonder they had a midnight deadline eh?

I’ll stick to human interest here but Chief of Staff Susie Wiles appeared to be wearing a Whoop tracker in a secure room which was confirmed by the company’s CEO by tweet.

The original concern being that some fitness trackers break NSA protocols as they have audio recording and other data recording which wouldn’t be appropriate in a dark room type the situation room.

Interestingly Whoop is approved by the NSA for use in these situations. Per the CEO the Whoop does not include a microphone, GPS, or cellular capability of any kind and has long been on the NSA approved PED list.

I myself wear both an Apple Watch and a Whoop everywhere but I rarely need to be out of the prying ears of recoding devices but it’s good to know.

Whoop’s CEO joked that given the success of the mission Susie Wiles must have had a green recovery score (quality sleep, low resting heart rate and high HRV) though I imagine she must be feeling the stress now that it’s over.

I wonder if her score worse than mine. I needed steroids and antibiotics to manage the flare post dental work and my body is under more strain than you’d imagine.

It’s somehow nice to know that the most powerful people on the planet use the same tools as I do to track their biometrics. From billionaire founders like Bryan Johnson to the Chief of Staff of the President to little old me. We all wear the same track. If you want a referral code here you go.

Categories
Medical Politics Preparedness

Day 1885 and Take It Down A Notch

The tension that has gripped geopolitics since the America build up began in the Middle East in late January, came to a dramatic head today.

A kerfuffle over the department of war’s contract to use the current best in class AI deployed on hyperscaler approved sandbox clouds naturally took up a lot of the energy the night before the real story got going. Great distraction work.

Iran launched large salvos of ballistic missiles and drones targeting U.S. bases across the Gulf and against the UAE, Qatar and Bahrain as part of a wider regional response.

The airspace being closed across the region, a lot of moving pieces at play means one can only pray for those in harm’s way. And that cooler heads can convince old generals not to use their youth for death.

I don’t feel all that well myself. I am glad to be far from the region. I have inflammatory symptoms popping up after my dental work but I hope it is soothed by antibiotics and now a dose of steroids.

I am itchier than seems sensible. I don’t know why but maybe general stress likes to compound itself with irruption.

I’d like to enjoy fair weather and beautiful sunsets before things change for the worse. I’ll do my best to work for things to go better but it’s a big job and we all must work towards it as best we can.

Categories
Medical

Day 1884 and Post Op Shop Bop On The Head

I am a stricken by the malaise that comes with minor injuries. Yesterday I had some dental work done (with a laser) and today is all wretched inflammation.

An affliction that requires recuperation gets me down as I can’t say I’m really miserable or in much. I live with worse pain whenever I flare with my ankyloysis. I just feel pretty shitty and my brain is slugging slowly through the muddy waters of stress toxins.

It’s m the mixture of stress, antibiotics (doctor recommended prophylactic course given my soft tissue infection risks of my biological injection) and the tide going out in the cortisol. Being flooded with cortisol is not just a meme.

And so I don’t recommend being this in this state, but you also need to do proper care and maintenance of things like healthcare. And your teeth are a core part of this. After a certain age you can’t just ignore problems. And so I’ll be on Twitter as I can’t concentrate well enough to do much useful today. And my husband will kill me if I do any more cosmetic shopping.

Categories
Aesthetics Medical

Day 1883 and Fill Me Up

I mentioned yesterday I needed to get my lower left molar 19 fix up. The filling placed there long ago by a dental student wasn’t holding up well and looked pretty nasty

A warning for the squeamish that I am going to post before, during and after photos. If things like gums, blood, funky messed up teeth close ups are upsetting to you this is where you should stop.

I was schedule for an hour as molar 19 needed a new filling while 20 was also looking a bit funny as well. First they carefully numbed the left side of my mouth which always feels weird. You feel no pain just pressure. Which is an experience I’ve had a few times this year.

A cleaning was required as well as a cool laser which smelled like popcorn as it zapped out the damage areas.

These hard‑tissue dental lasers (mainly erbium) ablate tooth structure by rapidly heating water and hydroxyapatite in the tooth, “micro‑exploding” tiny amounts of tissue rather than cutting mechanically like a bur.

Erbium laser preparing teeth decay for a small filling on 19 and 20

These systems are typically used for small‑to‑moderate decay especially when soft tissue injury is concern. These lasers can mean less pain and less anesthesia is needed.

A composite filling matched exactly left my teeth looking as good as new. My mouth is still a bit numb but I’m glad to have things fixed up with relative ease. Now I can only hope the healing goes easy as well.