Year: 2025

Categories
Biohacking Medical

Day 1723 and Hormonal Rollercoaster Rides

We spent a long time at the doctor’s yesterday as Alex and I gutted it out with our excellent physician (with AI assists) through a myriad of different tests. We were attempting to figure out why he keeps getting respiratory infections and why I’m such a tasty treat to skin bacteria.

In truth, my basic inflammatory biometrics have improved so much on the new IL-17a inhibitor Bimzelx that it’s probably worth the hassle of occasionally having to slice open a random effected gland or abscess once a quarter. It’s just a shocking amount of work to do whack mole with pathology reports.

What I don’t seem to be able to improve is my low testosterone and the flavors of migraine headache that come with the roller coaster of my luteal phase. Which is presumably a clue and we are following it.

Astonishingly my lady hormones are in tip top shape. Though the “you should have no trouble getting pregnant if we can get off the medicines that stabilize you” remarks remains a heads trip. Yes I asked.

It is not a head trip that makes one’s husband enthusiastic about the prospect. Which is fair, as we have no family support, no backup plans for me regressing physically, and the family that does support us can’t get to America. So one can see why a CEO husband with sick investor wife who would have to give up work, plus potentially messed up baby, isn’t super appealing. Anyways! TFR is a fun topic.

I started with basic supplements in the precursor category like DHEA and STRO about a year ago when my testosterone came in at a 2 nanograms per deciliter (ng/dL) when it should be somewhere between 9 to 55 nanograms per deciliter (ng/dL). For context, adult men typically have levels in the 240–950 ng/dL.

The one sticky widget is that my testosterone remains stubbornly low. You wouldn’t think such a raging “see you next Tuesday” such as myself would be overburdened with the feminine hormones and lacking in ball buster hormones but I am.

I managed to eke it up to 5 with supplements and nutrition but it really didn’t match my otherwise excellent hormonal profile. Having ruined my chances at a healthy immune system when we tried the first half of IVF, I’ve spent some time working on and with my natural cycles.

Good information for all humans

I loathe being in my luteal phase but when I’m in my follicular phase I get 90% of my work done. We had presumed it was the rapid decline in estrogen and progesterone but maybe my floor rate testosterone was more of the issue.

For the past 8 weeks I’ve been using a testosterone cream that clicks up your dose and you rub it between your thighs. I know it’s gross. So I was curious to see where I might land. And praise the Lord I am now at 15 ng/dL. From 2 to 5 to 15 is some excellent progress but still below where we’d like me to hit. So we are going to run another test and try out the tiny pellets they slice into your skin. Since I’m already used to scalpels and antibiotics I figure why not?

Categories
Culture Media Politics

Day 1722 and The Remake of The People versus Larry Flynt Sucks

I have not watched Jimmy Kimmel in his current incarnation as broadcast late night variety show host. But I did watch some episodes of the Man Show so I’m not entirely unfamiliar with the man’s career.

This guy is into beer, boobs and being turned down by ABC

That one unremarkable but sort of likable dude can jump from hosting segments about girls on trampolines to a national broadcast host with political opinions is somewhat impressive and also bleak.

If I had to give mono-causal explainer as why millennial women seem split into two distinct political camps when it comes to modern American politics, absolutely over it or absolutely irate, I think the continued existence of Jimmy Kimmel’s career would be as fine an explanation as any other.

This guy gets promoted over and over for just being the worst and what do we get? We get scolded no matter what we do. Of course some women are screaming banshees and the rest are like mmm shrug. Who has freedom and who has responsibility has always been a polite fiction.

Being subjected to years of increasingly sexualized entertainment featuring bouncing boobies, mentally unstable underage pop stars and the men who were paid to ogle them professionally probably had some downstream influence on our current political climate and the shitty state of entertainment.

The backlash to the backlash to the backlash as it were has happened and we just don’t care anymore. I’ll fight for your right to be perverted but I won’t lie to you and say it hasn’t negatively affected me in anyway.

I’ve always been acutely aware of where popular culture derived a women’s value. Jimmy Kimmel had a career and Britney Spears had a breakdown. And now you want me to fight to keep this twerp on the air because of our proud democracy and its culture of promoting speech and expression? Fuck off.

I genuinely believe girls on trampolines has inherent entertainment and artistic value. Almost everyone has an appreciation for the female form.

I’m unclear if warmed over political takes on broadcast television delivered by a middling broadcaster at midnight is more or less valuable an art form or as political expression. Maybe the FCC needs an overhaul for this new era or maybe we get pirates wires.

I’m neither a satirist nor comedian. I watched the Man Show because I had a boyfriend in a fraternity but I am not watching Jimmy Kimmel’s monologue now and neither are you.

And that’s all that matters to the business of entertainment. Slapping speech and politics on it is a reach that now middle aged millennials can’t manage. Maybe if we spent more time on trampolines.

Elite competition skirmishes over who controls the airwaves of broadcast television are barely interesting except to the absolutely irate. And these days we are all too busy to remain irate unless we’ve got luxury signaling to do. Which I don’t need to do because no one is coming for my blog.

I don’t see how anyone can turn a microwaved soggy ready meal remake of the people versus Larry Flynt out of Jimmy Kimmel.

Who wants to fight for that? Hustler had some inherent entertainment value and Larry Flynt had “readers.” It was speech and it wasn’t on public airwaves with a boss in Washington DC. Maybe you didn’t like what he did but were you prepared to fight for it? Lots of people were. Who wants to fight for Kimmel?

Oliver Stone has always been kind of a shitlib

Jimmy Kimmel was never anything more than the guy who read cue cards between the dopamine hits of girls on trampolines. Stuffing your politics into his pie hole doesn’t really change that.

Bob Iger knows it. I know it. The guy had dwindling ratings, an expensive contract and not nearly enough common sense to keep his mouth shut if one of his staffers was out of touch. If I were in charge of Disney that would be my excuse and I’d dump that Jimmy for literally anything else. I bet a swearing parrot would test better. Hell I know it would.

That’s why it’s so damned exhausting to care about the free speech that literally nobody asked to be said. Does anyone who genuinely cares about free speech feel like they can rally the cause to a bobble head spouting opinions that aren’t even his own? Doubtful. I’d sooner fight for Illinois Nazis. Shame about the ACLU innit?

Americans would rally for boobs though. If someone wanted to get the FCC to allow the return of the Man Show and place it on ABC after dark maybe then we’d have a worthy sequel to Larry Flynt.

But nobody is going to bat for Jimmy Kimmel unless it’s backed up with boobies. And there isn’t a perky tit in sight. No one is going to make a political meal out of this. I doubt even the Swanson’s heir could heat this frozen turd.

Categories
Politics Startups

Day 1721 and Valar, Inference dot Net and Policy for The Future

There has been such a bleak mood on the timelines as Americans are once again locked into a cycle of agitation and propaganda driven by hyper persuasion A/B testing of rage bate as tragedy turns on the opportunism machines. So I’d like to share bits and bobs of good news in my corner of the world today.

Valar Atomics is one of my proudest true first check investments. I knew Isaiah was special from the moment I met him. But I didn’t like the company he was pursuing with someone. I said I’d back him in something else so long as he was the CEO. I’m so glad I told the straight truth as Isaiah let me in on his true dream of an energy abundant nuclear future and I was able to be there from day before zero.

Valar is audacious, ingenious and the kind of hard technical work I’d never seen anyone raise from his position as self taught young man. But what a challenge right? I was in. I believe in him. And boy do I look smart now.

The Valar Atomics and Kiewit announced a groundbreaking at the San Rafael Energy Research Center for Ward250, their very first reactor! It is a major step on their mission to answer the President’s call for three advanced reactors on American soil by July 4, 2026.

If you want to watch an inspiring video with a Blackhawk click through. Kiewit is America’s 2nd largest power plant builder, with more active nuclear construction projects than any other company in North America. Utah deserved a win like this today.

Valar is incredibly grateful to the State of Utah, especially Governor Spencer Cox, DNR Executive Director Joel Ferry, EOD Director Emy Lesofski, USREL Director Jaron Wallace, and all our local partners in beautiful Emery County.

Chaotic portfolio founder, and once and future Montana guy, Sam Hogan has a good synopsis of CogSec 101 in times of tension that I thought I’d share as a teaser for introducing his fantastic compute company Inference.Net

He gives good being online advice and his company Inference.net (yes disclosure investor) just started sponsoring a new podcast about the culture of San Francisco.

It’s called Member of the Technical Staff. It’s a fun hang with perennial grist for the social mills topics like where are the girlies in San Francisco. It’s a hang for a subcultural issues relevant to understanding living in a boomtown while building.

In local Montana news, we have had national influence with our work supporting the Frontier Institute and its indefatigable leader Kendall Cotton. Must be something about this Rocky Mountain boys that we love. He’s proving you can just do things.


I’m thrilled to report that two model bills that we’ve pioneered in Montana were officially adopted as ALEC model policy. This means that state legislators from across the country who look to ALEC for ideas will be prompted to introduce their state’s own Right to Compute Act (recognized as the gold standard for state tech regulation) or Private Property Protection Act (a cutting edge approach to zoning reform focused on housing affordability). 

We’ve officially become a national policy leader – a big deal! We’re a small state, and a small team here at Frontier Institute, but we’re making a huge impact thanks to supporters like you.

And that supporter like you? Heck yeah those supporters are me and Alex. .

You two can just do things as our boys Isaiah, Sam and Kendall have shown. You can build nuclear reactors, run decentralized inference compute markets and create new models, and even change your state’s policy with better laws that become models for the entire nation.

Categories
Biohacking Reading

Day 1720 and I Am OK To Go

I love Carl Sagan’s Contact. I first read the book in my middle school years and was allowed to watch the movie starring Jodie Foster despite having a very limited “screen time” diet.

As I got older I was allowed to watch edifying science fiction and book adaption only if I had read the source material. Contact passed both tests

It’s a beautiful story of faith and science about on a radio astronomer who finds a signal from alien intelligence which kicks off a planet wide space race to make contact.

There is a scene in the film where our protagonist Dr Arroway is set to launch a machine which we humans do not fully understand but is presumed to be some sort of transportation device.

Just as the countdown nears zero, she loses contact with the ground team. Roaring machinery and turbulence drowns her voice as she repeats over and over “I am OK to go” until a blind colleague finally picks her voice out of the static. The capsule is let go. I won’t spoiler it.

I’m OK To Go

I had a little moment of being out of contact myself today. I am now the proud owner of a hyperbaric chamber but still getting used to the machine. Alex, watching me as I adjusted, communicated with me through the glass with gestures.

Hyperbaric chamber oxygen therapy has roots in diving as managing pressure changes is an important aspect of safety for underwater and high altitude work.

When diving you don’t give a thumbs up to show you are alright. Thumbs up actually means ascend. You give the OK sign to communicate that you are doing fine.

The “OK” hand signal in diving is formed by touching the tip of the thumb and index finger together to make a circle, with the other three fingers extended upward.

Even as I was a little dizzy and struggling to acclimate I was ultimately “ok to go.”

Categories
Biohacking Chronic Disease Medical

Day 1719 and Biometric Fall Lock In

I slept rather poorly last night. I get anxious before medical appointments. Interfacing with America’s medical system can range from merely uncomfortable to actively hostile so I suppose some heightened vigilance isn’t irrational.

I wanted to get a fresh set of bloodwork after a summer of fairly involved medical intervention. It ranged from deep tissue infection discovered during a minor surgery to multiple rounds of antibiotics. I have experienced a lot of side effects at full strength.

I am also beginning a 40-60 session hyperbaric chamber oxygen therapy protocol and I thought it wise to get the basic bloods for a before and after purpose.

I really yearn for an uptick in qualitative metrics I associate with higher quality of life like energy for my favorite physical activities (weightlifting and hiking). The fatigue and stress from the pain, and downstream side effects are constant reminders of poor health.

So I am looking for improvements in basic markers like my CRP and Sed Rate as those inflammatory markers should coincide with the qualitative improvements.

Categories
Aesthetics Reading

Day 1718 and The Abyss Stares Back

The glory of the first few weeks of fall in Montana, indeed most of the mountain west, is under appreciated.

We advertise the powdery snow & bright sunshine of our winters and the long temperate days of our summer for tourism, but I love the precious few middle days of transition as we approach Michaelmas season.

The harvest wraps, the fall begins in earnest with frost ever ready, and we prepare ourselves for darker days ahead.

I personally try to be outside as much as possible in this transitional period. Throwing on sneakers and a vest is much easier than snow boots and a parka.

Rambling across county pastures, over makeshift bridges across streams and across neighboring fields in the morning sets the tone for a positive day.

Someone acquired a new piebald

Once I’d returned home, the abyss of the open internet was there to stare back at me as I looked too hard upon it.

The prayers I had uttered in thanks for the glory of our mountains, the brightness of the sun, and the mercy granted to the living was pushed back by the darkness of greyzone algorithmic memetic warfare.

I am still recovering from travel so weak enough that I have little desire to self censor. The ebbs and flows of conflicting constructed realities are fighting for purchase on the American mind and it’s not pretty. God given inalienable rights are not on anyone’s mind when there are others to blame.

I hardly knew if I should pick up Heidegger, Nietzsche or (shuddering at the thought) Schmitt to make sense of apoplectic displays of poorly harnessed power being thrown about by competing and angry egregores.

What could I possibly do or say or read to make sense of anything? I suppose that’s how the abyss gets you. The Nothing only needs you to stand idly by as you are absorbed into the abyss. Michael Ende and Madeleine L’Engle may be better places to go to understand the abyss than Nietzsche. Lest we lose our sense of wonder in the horror.

Die unendliche Geschichte – 1979 Michael Ende

Categories
Biohacking Chronic Disease Medical

Day 1717 and The Beginning of My 40 Treatments of Hyperbaric Chamber Oxygen Therapy

An auspicious pair of numbers for today’s date and I started something new which has been in the works since January began today. Our long awaited hyperbaric chamber has arrived and been fully set up in our yellow barn.

A lazy boy lounger and oxygen under two atmospheres of pressure.

It feels good to begin a positive focused wellness activity after what was otherwise a chaotic week of travel, geopolitics and violence.

As expected, it is not fun living through my own investment thesis. So you better believe I test my theories on myself. I want to survive the Jackpot.

Before Trump’s inauguration, we decided to purchase a hyperbaric chamber after one of our mutuals told us about his HBOT trial at a conference in the fall. It went very well for him and the research is promising for inflammatory conditions.

Over the winter break I happened to be in a city where I could test HBOT cheaply and was very impressed with the results in only ten sessions during a flare in my autoimmune condition. Crimping from Bryan Johnson

Hyperbaric Oxygen Therapy (HBOT) involves breathing pure or nearly pure oxygen (95-100%) in a pressurized chamber at anything above atmospheric pressure (2 ATA is equivalent to being 33 feet under seawater).

The increased pressure enhances the lungs’ ability to absorb oxygen, boosting oxygen levels throughout the body. The therapy aims to promote rejuvenation by increasing oxygen concentration in tissues, supporting healing, cellular repair, and vascularization.

This sent me down a rabbit hole as I did a bunch of deep dives, got some text books and came to a simple conclusion after a lot of medical papers that it’s pretty simple.

It’s almost philosophically the way of life in the mountain west. Oxygen and pressure work on the biomechanics of a functional body. Alas getting my basic market model to Montana ended up being a cluster fork of issues. We placed the order in January.

For months we waited for what we’d been told would be a 6-8 week process. Alas all hell broke loose. We had tariffs uncertainty with the importer and the OEM.

Then Liberation Day looked dire which led our machine in a Chinese port hold which launched a trip to Istanbul to source the finest HBOT machines money can buy. I still intend to acquire on.

I have now, in September, after a long journey but a simple set up process, begun my first intensive protocol for autoimmune diseases on our own hyperbaric chamber.

Love your body enough to put it under pressure and take a deep breath.

I will complete a minimum of 40 sessions (5 sessions weekly) at 2 atmospheric pressures, in a hard chamber from OxyRevo with each session 90 minutes while breathing 100% oxygen for 20 minutes separated by a 5 minute break.

If you are interested and see strip mall options note that these are not consumer grade machines. The protocol requires a hard chamber to achieve that pressures. It’s quite a bit higher than soft chambers on the market.

There are risks associated with HBOT from correct pressurization issues to impacts like tinnitus. The more prepared you are to adapt to changing pressure with breathing techniques and equalization (looking to divers for these protocols) the happier your central nervous system will be.

Take control
Categories
Internet Culture

Day 1716 and Algorithmic Nihilism

I am quite jet lagged today so I am unsure if this will be coherent but “it’s practice” so here I am.

I am in the middle of my own biochemical storms as the wider algorithmic storms of the web remain at hurricane strength. My own teapot tempests hardly matter against the gale force nihilism of the raw power games buffeting us all about this online.

I suggest reading Katherine Dee’s post on online political subcultures if you are feeling confused about the infighting and schismatic nature of networked political culture on social media.

The phenomenon KiwiFarms calls “Zoomer sadism” — surreal, absurdist cruelty now endemic to so many online spaces, is not confined to the right alone. The disembodiment and desensitization that define life for so many under 45.

Since I began writing specifically about online nihilism in 2022, the FBI has even created a new domestic extremism category: NVE (nihilist violent extremism). These aren’t fringe concerns — or even new ones, the Internet didn’t invent this particular despair, it only gave it new outlets — they’re central to understanding what’s happening online. Default Blog

Nihilism being algorithmically amplified has given audiences to people who might have otherwise been dismissed as cranks, loons, and agitators in the past.

To have a counter culture meant having a dominant culture to press against. Now we have a thousand splinters and millions of different audiences to that splintering fighting symbolic battles. That they are spilling into real violence isn’t new, surprising or even native to the Internet.

It’s merely that we are being fed into the maw of reinforcement learning and algorithmic preferences until we have nothing left but smoothed archetypes battling tribal signals.

That we see people who takes these symbols to a violent extreme should be the expected outcome of persistent othering by algorithm. Digital cultural scissoring breaks apart the collective “we” of all types affinity from national and ethnic identities to sexual preferences and other more abstract ideologies.

Just remember that if a group kicks out too many people they may find themselves with nothing left but sycophant audiences driven by adaptive code. And while that may sound scary, I agree with Lebowski that nihilists are nothing to be afraid of when you are sure of your own principles. So take stock of what matters to you and feed that back to the algorithms. Despair only wins if you let it.

Categories
Travel

Day 1715 and My No Good Horrible Very Bad Transit Day

As I often do on transcontinental travel days, I wrote my post for the day first thing in the morning. I wasn’t sure how the journey would go so I thought “let’s post this early” in case things get hairy. And boy did it.

I was leaving Europe just as Poland closed its airspace after a Russian drone attack. Tensions were already high as Israel had attacked Hamas inside Qatar’s capital of Doha. Greyzone war that blur attacks on national sovereignty through target or weapon choices make everyone twitchy.

It’s a weird thing to complain about air travel on 9/11, but I don’t think much of the security theater we’ve accepted over the years did much to keep my transit safe yesterday. Twenty four years later we go through the motions of keeping air travel safe from terror because what else are we going to do?

In fact, it didn’t seem as if security was particularly tight yesterday so much as particularly incompetent. It was chaotic confusion everywhere from passport checks to boarding flights.

I had a Frankfurt to Chicago polar day flight, along with a positioning flight on each side. I went through a lot of security screenings and passport checks yesterday and stood in more lines than I can count.

In Frankfurt the lines were so long that even with planned two hour airport transit time, I was among the last to board my flight.

The “special purposes” line I begged my way into as my inbound was delayed by fog was glacial in its pace. It seems the new transit grift is wheelchairs. So perfectly abled people are now pretending at disability to board early and use special security screening lines.

It left wishing I’d registered my real disability as I attempted to run the two miles of the international terminal with suitcase and backpack torquing my spine so I wouldn’t miss my flight to Chicago.

Deplaning at Chicago I couldn’t even count the full set of wheelchairs waiting.

Add in enormous confused families using the special purpose line, who spoke neither German nor English, with 3-4 bags a piece and every sort of banned item from pocket knives to 1.5l bottles of liquids and I am shocked anyone made it through security to their flights on time.

I watched a foursome of black Arabic speaking grandmothers in hijabs and wheelchairs shouting at German security guards and their extended families as I waited for my turn. Their fierce attitudes did not speed anything up that I could tell.

I saw them 9 hours later gathering somehow even more checked luggage upon arrival in O’Hare. I’m glad my Global Entry let me pass them by at passport control as I did not want to be behind them again.

Not that I got through Chicago’s security lines unscathed. The TSA pre-check lines were four times as long as the regular line. Figuring I was well packed I could handle the normal line. Naturally I got randomly selected and unpacked basically everything

As I stood in my socks waiting for the agents to stop gossiping and listen to the only working agent explain to them that “yes that the ice pack was for medications so they can move this along” I got an alert on my phone that the conservative political organizer Charlie Kirk had been shot.

I wandered in a daze to the United club where I was denied entry. This despite booking a business class ticket for the entire transit through their own hub via their Star Alliance partnership with Lufthansa, I couldn’t use the club as “the last leg of my flight didn’t qualify.”

I knew this was possible as this last leg issue happened to me on my last transit through O’Hare so I’d bought a day pass ahead of time. But they weren’t honoring those as it was too busy. I schlepped to another club in the terminal where they were still letting in day passes. There I listened to scared speculation from two blonde women about Mr Kirk’s status.

Another hour later I made my way onto my flight to Montana. I decided to just jump to the front of the line as I was in first with seat 2B. If everyone is ignoring lines then it was irrational to keep trying to politely queue.

As the plane boarded it was all talk of Mr Kirk. A news alert crossed my phone saying he had been killed.

A gentleman was playing a video of stitched together angles of footage on his phone with full audio on. You could hear the bullet hit again and again.

The cabin attendant told him to turn it off, saying sir please have some respect for the dead. A few hours later, still living, I made it home to Montana.

Categories
Travel

Day 1714 and Bum Rush The Airbus

I’ve got a long travel day ahead of me with multiple transit hops. Given the state of geopolitics, I expect the international hub that is a transit point for most of the better MENA carriers will have some extra security measures.

In situations where I know my planned itinerary could go awry, I have my three bag cascade system.

I always pack a toiletry bag that can manage all grooming for at least 3 days, all crucial medications are kept on my body with a full supply in my backpack and finally a change of clothes should I find myself with an overnight.

Match-y Match-y

If you are interested I use Aer, Muji and BagSmart and a labeling system so I always know where things are. I’ve found having extensive labeling really makes the crankier airport workers in big hubs like Frankfurt and Heathrow happy.

Boarding a Lufthansa Airbus 321

We got the hurry up and wait now that we’ve boarded in a clusterfork of infrequent travelers who insist on manners like rushing the doors when they are not in the proper class and bringing 3-4 pieces of luggage.

Watching an older lady throw a fit in broken English to a German flight manager that she should have the open space in business class because no one is using it was funny. She didn’t understand that because it was a bum rush that many of the travelers in business and first were behind her.

We just got the news that Poland is closing its airspace after a Russian drone attack. Over 100 people on the plane on my first jump have connecting flights across Europe and internationally so I’ll be interested to see what things look like at the hub. Add in bad weather in Germany and I’m sure this will have some exciting moments.