Categories
Aesthetics Biohacking

Day 1756 and Oops I Did It Again

Oh baby baby! So it seems as if, in my infinite wisdom, I did not pay enough attention to the early warning signs from my Whoop biometrics and I did indeed need to worry about the fun and games of a subcutaneous tissue infection.

I swear that this IL-17 inhibitor drives me nuts. Despite its impressive effect on my inflammatory biomarkers, it leaves me very susceptible to skin infections. And I have to be constantly vigilant to the first signs of an issue.

I’ll be fine. I did in fact catch it before it turned into anything serious. Where I am at it’s easily treatable with a short antibiotic course that may formerly be prophylactic. My wound area had not shown any signs of spreading nor was I running a fever or otherwise exhibiting other signs of serious infection.

I just had crappy HRV numbers and high resting heart rate three days in a row and it’s not worth risking it. I threw back some basic antibiotics last night and woke up with a normal heart rate again. My HRV is coming up just a little more slowly. Glad I didn’t wait as this isn’t worth any amount of risk to me.

I comforted myself by working on my beauty blog where I’ve got routines coming along for founding subscribers and a fresh post about Shrinkflation at Sephora and a minimalist men’s routine on sale at Amazon.

Retailers are a bit twitchy and everyone needs to be shopping early is the message we are getting everywhere. It’s a weird time. Or at least the retailers need to encourage the top 10%. So if that is interesting to you go subscribe as I’d love to have you in my strange beauty shopping blog meets the business of appearance.

Or if you are feeling adventurous for an honestly embarrassingly low fee I’ll put together a custom routine for you from my sample library or go full autistic and decant you the perfect mix of potions and lotions to meet you precise lifestyle and budget. My autistic obsession is your gain. It’s so much for me for and your skin will look amazing.

Categories
Biohacking

Day 1748 and Putting Testosterone Pellets In My Butt Cheek

Intrepid biohacker that I am, when I learned that my testosterone levels were concerningly low, I began on a program to raise them.

I started with nutrition and supplementation but I already had a diet and supplement routine that was evidence based for raising testosterone levels in women.

I added in DHEA (Dehydroepiandrosterone) at 25mg. Six months of that brought me up to just about half of the lowest baseline acceptable. I was NOT getting adequate results.

My physician prescribed me a cream from a compound pharmacy which unfortunately didn’t agree with my skin. So we were going to get creative.

I had read a blog post from Cate Hall (whose husband Sasha Chapin had helped me on another entirely different vector of my life) on how testosterone pellets changed her life.

She had had teeny tiny testosterone pellets placed into her subcutaneous fat and had remarkable results in terms of energy and focus. This and that happened, and the summer was a mess, but today was the day I finally followed in her footsteps.

Vials of compounded testosterone

We’re started me with 10mg of estradiol (range 6-25mg with 8-10mg being most common), and 75mg of testosterone (range 50-150mg with the most common being 75-100).

We’ll aim for labs at 4-6 weeks after insertion which would represent peak levels. We will repeat dosing at 3-6 month intervals. We will check levels at 4 months or so, or earlier if I feel the effects waning.

Do be warned that within a paragraph or so, there will be images of needles, scalpels, and some blood. So feel free to not scroll down further.

Part of the difficulty with dosing this stuff is that the pellet doses are wonky and frequently out of stock – estradiol comes in 6mg and 10mg increments so 8mg is impossible.

Naturally, we’ve made surprisingly little progress when it comes to women’s health, particularly as it relates to hormones.

Prepared and ready to go

But as I am happy to be a guinea pig and my luteal phase is a mess of migraines and misery I figured I had little to lose and much to gain. I was the first patient my doctor has done the procedure on so if anyone in Bozeman is interested, you can confidently give it a go with him as I’ve survived it.

These cool tubes don’t actually go inside too far but sort of shoot the pellet into the incisions

I was given a local numbing agent with epinephrine. I needed a surprising amount of it but I was a bit nervous. Once I was just able to feel pressure and no pain it was time to make a small incision with a scalpel and in popped the tiny bit of hormone on the left butt cheek.

No big deal at all.

But if you don’t want to see it going in don’t scroll.

Just giving you space to turn back.

A tiny incision in my goose bumped bum with the little pellets easily tucked in

I am all bandaged up and still riding the cortisone of it all but I feel alright. I’ll be adding in progesterone orally to temper the estrogen as that’s another matter. I’m excited to report back on it as if I have even a fraction of Cate’s experience with it I’ll be quite happy. Also it’s about $70 a month so not cheap but not at all expensive for something that could potentially mitigate some long term issues I’ve struggled with for years.

Categories
Biohacking Chronic Disease

Day 1732 and It’s Getting Hot In Here So Take Off All Your Clothes

You might want bring towel though, as our handcrafted Finnish sauna will need some use before the cedar is completely smooth. Yes, that’s right, the MilFred family Yellow Barn now has a sauna. And she is a beauty. Just check out the view we picked for her.

Alex and the wonderful family who built the cedar sauna structure placed her under the back awning of the big yellow barn today. Wiring and electronics are underway as I write.

We’ve been slowly but surely turning our barn into our ideal wellness center both for our own use and eventually for the wider community as well. We are privileged with skills, capital and loads of very expensive personal experience with chronic illnesses.

So naturally as geriatric millennials it is always our instincts to turn our pain into something useful and also if we are lucky pay back the expenditures and turn a profit. Which we can then reinvest. It’s the circle of life for a generation who found the circle of life to be a tad more inflationary than expected.

The man of action putting the finishing touches on the electronics. We don’t have anything in our home systems connected to the cloud, so he built his own fully local controller with
ESP32 as the brains, 60a 240v contactor for heater, RGBW LED controls
UI/ final control via Home Assistant and HomeKit. You can snag the code on GitHub

In true MilFred fashion, we are building and testing everything all on ourselves. An n of 1 is good, an n of 2 is better, and if you’d like to test it out hit us up while it is a work in progress. Build in public and beta test with your friends.

Tucked under the awning of the barn so one can easily pop in from gym, HBOT or cold plunge to warm cedar comfort and mountain views

We’d like to ultimately build a space for healing, relaxation and training for those who prefer time tested modalities like heat, cold, oxygen and pressure.

Friends and family can come and test out our now very impressive range of equipment as we build this all out.

We have one of the few hyperbaric oxygen therapy chambers available outside of hospital use in the region. You can pressurize to 2 atmospheres and set a range of parameters for a range of treatments. I use it for my inflammatory condition while Alex is treating the remains of long covid. You’d be shocked what pressure and oxygen can do.

Our hyperbaric oxygen therapy chamber

If you want a work out get in some squat reps in our power cage, take a swing at the punching bag or lengthen your spine on our Pilates reformer. You can even climb around on the rock wall built into the the barn ceiling (not even kidding that is the work of the previous family).

If you are looking for a spa day you can have a sweat in the sauna, do red light therapy on your face, chill out on a PEMF mat, and hopefully soon take a dip in a cold plunge. Though if you are ambitious you can sprint across the front pasture and jump in our pond but I’ll warn you that the ducks might not love it.

The pond is fed by a creek that comes from the canyon above our house

The point being that we are building by hand and through personal experience something that improves our lives and others and that’s a pretty hot thing to do. Don’t worry, we will provide towels and robes if you do indeed take off all your clothes. Just come on over and try it out.

Categories
Medical

Day 845 and Fucked Fertility

A bit of discourse stirred up a lot of grief and sadness for me. Noah Smith did an analysis of the much discussed Atlantic piece “The Myth of the Broke Millennial.” His breakdown is excellent and I recommend the Twitter thread where several of my geriatric millennial friends weigh in on how late in life security has come for many of us and how precarious it still feels.

What jumped out at me most in Noah’s breakdown is whether millennials will feel financially secure enough to have kids if it’s indeed true that we are getting less precarious.

That matters as a question as having children appears to be a driving force towards conservative politics but also a general preference for less government involvement. Noah wondered if millennials will be less woke and less inclined to socialism if we don’t turn out to be downwardly mobile. The theory is we might be if, and it’s a big if, we feel secure enough to have children.

There is one age-related factor that appears to draw people to the right, however: having children. Fertility rates are down, and Twenge discusses some reasons for this in her article. But what really matters for politics is probably not the number of kids that get born, but the number of people who end up having any kids at all.

I’ve got bad news on this front as the first wave of elder millennials who haven’t already had kids probably can’t. Why? Our women are aging out of fertility before they find the security they feel they need to consider having kids.

By the time millennial women get to a place where it seems feasible we’ve long entered “geriatric pregnancy” territory. I froze my eggs right before it was considered a geriatric situation. Which is give or take 31-32 now as we redefine fertility. I am now 39.

Now that’s a longer story for me personally as freezing my eggs felt like a consumer decision, was marketed as insurance policy, and ended up being a life changing catastrophe. And I still don’t have kids.

The process of egg extraction triggered an inflammatory disease and I may never be able to carry to term. And I have complicated grief stricken emotions about the entire affair. And we spent a small fortune getting me healthy enough to go back work.

But my suspicion is that many millennials will learn that fertility isn’t as easy as they imagine if they try to deal with it past 35 let alone past 40.

And we simply cannot seem to discuss the issue in a way that is productive. The discourse is toxic as cultural warriors, often men weigh in with their complex emotions about what it means to have a family, support children and generally deal with women’s health.

Shaming and controlling women’s bodies doesn’t really do much for the cold hard reality that we failed many millennial women by assuring technology could solve for the hard questions on fertility. So we marketed these new medical options and sold it at premium. Silicon Valley mounted a whole campaign to freeze eggs for its female workforce.

I’m afraid we are too deeply entrenched in a culture war to discus this productively as most of the people I see with the message that fertility is complex tend to view things in a more traditional context.

I personally love playing a tradwife on Twitter because I’ve learned a lot about how reactionary feminists and baroque online misogyny views motherhood. They talk to me and I’ve listened.

But we need to get women of all politics and preferences and family structures involved in this conversation as a full decade of millennial women are going to need to consider their relationship to their own fertility and bodies in short order. And for many of us it’s too late.

Treatments like IVF and egg freezing & extraction are expensive and have considerably more risk than we are comfortable discussing. Surrogates are a quarter of a million dollar expense which disgustingly is for bureaucratic costs not the surrogate herself. If you want multiple children it’s not crazy to plan for a million dollars. And don’t get me started on how adoption plays into all of this.

A generation of fucked fertility with myriad corporate profit motives driving decision making sounds like the stuff of conspiracy and cranks but don’t be fooled by extremism. We’ve done a shitty job investing in women’s healthcare in America and it will have consequences.

I know it’s scary to look at head on. I regularly break down with my own grief on the matter. I’ve been looking at it for years. Having a serious health crisis brought on by family planning has been a blessing to my marriage but that blessing has enormous costs. I’d expect this process of addressing the fertility of a generation of women to be challenging for us all no matter your personal choices or politics.

Categories
Chronicle

Day 253 and Lady Troubles

Occasionally I find myself annoyed that women’s bodies are less studied than male bodies. You’d think we’d want to know more about the vessels that produce the heirs to make fortunes. Grumbling about mishandling property rights aside, I do wish we knew a little more about women’s health.

I get migraines when I menstruate. If that particular tidbit of information is too much for you well sorry but maybe it might be helpful if the basic biology of women’s bodies were a little further to the forefront of cultural consciousness. Women talk about it with each other which is why I’ve got a host of folklore on cramps, bloating, headaches, sore breast, and emotional rollercoasters.

I’m fairly lucky to have migraines. It’s marginally more pleasant than what my friends with heavy flows or bad cramps go through. And I say this just having vomited from the nausea that comes with my migraines.

And on that note I’m signing off as I only went on a tangent about the need for more effective study and treatment of women’s health as it’s the only thing I can think of to write about. And I committed to writing something every single day. So here I am writing through the migraine. I bet tomorrow will be more interesting. And I’d be thrilled if later in life we solve for the interplay between hormones and headaches so I never write about this topic again.