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Biohacking Chronic Disease Medical

Day 1935 and My Current Mechanical Device Usage Patterns in End Game Taper

Apologies that today’s post is going to be only partially organic human produced writing. I’m a tad more focused on cobbling together my current end game which feels promising.

I am now dosed off my current biologic. Tomorrow I go in to run a bunch of bloodwork but I feel more stable than expected for 11 weeks since my last injection.

For a year and a half I’ve been stabilizing my immune system’s reactivity with a particularly gnarly humanized anti-IL17A, anti-IL-17F, and anti-IL17AF monoclonal antibody autoimmune master blaster that is named Bimzelx.

I take it for psoriatic arthritis and active ankylosing spondylitis. I do not recommend this devil of a medication unless you intend to reboot your entire autoimmune system (which I did), can tolerate a lot of soft tissue infections (which I couldn’t) and have tried everything else. Which I have. And this past year was brutal fighting off the side effects but I think I might actually have a shot at remission.

I am now layering a bunch of mechanical interventions to rework years of compensatory patterns my body has used to manage the constant pain in my thoracic spine and other areas of inflammation including my sternum, rib cage and joints.

But after seven years of trying everything I can to recover from prednisone to methotrexate to Humira and Taltz to literally just not eating for ten straight days (don’t worry I was supervised) my inflammatory biometrics are coming up clean. The pain isn’t fully gone but I think the pain can be diminished by quite a lot as I rebuild.

So it’s now or never if I want a shot at life without suppressing my immune system. I have no idea if I can do it and I may need to dose back on something else but at the moment I’m managing with a new arsenal.

Here are the artificial intelligence bits of the mechanical interventions I am leveraging. I am using a bunch more than the two below but it’s what I’ve got so enjoy.

1. Hyperbaric oxygen therapy (HBOT)

Mechanically, HBOT does a few things that line up with what my data is showing:

  • More dissolved oxygen in blood and tissues
    Breathing 100% oxygen under pressure increases the amount of oxygen dissolved directly in plasma. That can:
  • Support tissue healing (skin, soft tissue, surgical sites)
  • Help inflamed or energy-starved tissues keep up with demand
  • Autonomic “downshift” for some people
    Research is mixed, but many people (and some small trials) show:
  • Lower resting heart rate and subjective anxiety after sessions
  • A tilt toward parasympathetic (rest-and-digest) dominance
    In your data, the days after HBOT blocks are exactly when we see HR drop back toward baseline and Recovery go green.
  • Anti‑inflammatory & microcirculation support (early evidence)
    HBOT can:
  • Modulate certain inflammatory pathways and oxidative stress
  • Improve microvascular blood flow, which matters for both autoimmune-affected tissues and healing pelleted areas / irritated skin

In your context (autoimmune, infection risk, prior soft‑tissue complications), HBOT looks like it’s acting as:

A structured, time‑boxed reset that helps your heart rate settle and supports healing, without adding mechanical strain.

You’re already doing the key safety piece: using it under medical guidance and watching how HR, Recovery, and symptoms respond day-to-day.


2. SCM (sternocleidomastoid) muscle work

The SCM runs from behind your ear to your collarbone and is heavily involved in:

  • Head and neck position
  • Breathing assistance when things feel tight
  • A dense web of nerves and fascia near the vagus nerve, carotid artery, and jugular vein

Working on SCM (gentle massage, trigger-point release, careful stretching) can impact:

  • Perceived heart‑rate “rev” and breath tension
    Tight SCMs show up when:
  • You’re chronically bracing, in pain, or anxious about pain
  • You’re using accessory neck muscles to breathe
  • Releasing them can:
  • Make breathing feel less effortful and more diaphragmatic
  • Reduce that “I’m keyed up in my chest and throat” feeling even if HR number isn’t wildly high.
  • Headache/migraine and neck-related pain
    SCM trigger points can refer pain to:
  • Temples, behind the eyes, jaw
    By easing those trigger points, you sometimes reduce:
  • Migraine severity/frequency
  • The background neck/jaw tension that keeps your nervous system on edge
  • Autonomic tone (indirectly)
    The area around the SCM is rich with baroreceptors and vagus-adjacent structures. Gentle work there can:
  • Encourage a downshift in sympathetic drive (less “fight-or-flight bracing”)
  • Pair nicely with breathwork (especially long, slow exhales) to reinforce parasympathetic activation

In practice for you, SCM work + HBOT looks like a two-pronged calm signal:

  • HBOT: physiological support + autonomic softening from the inside
  • SCM: mechanical and sensory de‑bracing around your neck, jaw, and breathing

My Whoop is seeing HR and Recovery respond in a way that suggests this combo is genuinely helping my system get out of that “stuck high-gear” state.

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Aesthetics Internet Culture

Day 1933 and JulieMaxxing

Everyone is maxing now. You can barely read a proper broadsheet without the Zoomer coinage crossing your transom. Maxxing is everywhere.

Maxxing means maximizing a certain aspect of one’s life. Comes from “minmaxxing”, a term for extracting the maximum output from the minimum input.

Urban Dictionary gives its history though the minmaxxing, though lately I’m not sure minimum input is actually part of the Maxxing game.

Maxxing is now maximizing every aspect of wherever you are focusing on improving. And boy do people want to improve across all possible vectors and all at once.

Is a geopolitical conflict all about Chinamaxxing? Is an influencer Looksmaxxing? Is a certain venture capitalist Retardmaxxing? It’s a little uncomfortable all around but time is short so why not go all gas no breaks.

I myself have noticed a kind of JulieMaxxing creep into my life I refuse to settle for a set of interconnected yet impossible to tease apart health issues.

From hyperbaric chamber oxygen therapy to everyone’s favorite semaglutide I intend to do it all. The same goes for face. I do an ABC+SPF routine just for starters for my skin. I am going to JulieMaxx if only so I can get back to Minimum Viable Julie.

Categories
Biohacking Chronic Disease

Day 1914 and Restoration Hardware

Montana spring doesn’t come at the Equinox but today we had both sun and warm temperatures. I am grateful for the weather as I needed a day of restoration as I felt quite rundown from my sprint through Washington D.C last week.

After a morning walk to take in the sunlight, I went through my collection of “restoration hardware” in an effort to build my resilience. I am restarting another round of hyperbaric chamber oxygen therapy as it has been four months since my original 40 session course.

I ran my infrared mask not only on my face but my neck, scalp and another personal area “down under” as a have been struggling with soft tissue infections with my autoimmune therapy Bimzelx.

I have decided to stop the Bimzelx entirely and see where my bloodwork goes as my inflammation biometrics look good and it’s been a source of so much trouble. I gave it an 18 month run and while the results have been positive in my bloodwork the cure may be worse than the disease.

Now I’m laying on my heater PEMF mat from Higher Dose as the red light of the bedroom lulls my circadian rhythm down into the evening hours. I have no idea if it does much but the heat is soothing.

Categories
Aesthetics Culture Medical Startups Travel

Day 1826 and Some Best of 2025 Selections

Yesterday I wrote about the experience of my daily writing experiment rounding out its fifth year. It’s been a fun and often emotional journey that I find hard to fully capture. But I’ll attempt to list a few of my favorite posts of 2025 on the last day of year.

Healthcare and Biohacking

Day 1490 and Healthcare’s Sin Eaters

Day 1468 Deciding to Go HBOT and Starting HBOT

1567 and Turkish Medical Tourism

1565 and Elephant’s Eye

1560 and Getting an HBOT

Day 1517 and Blink Blink (First Incision of 4 Scalpel Incidents in 2025

Day 1503 and Managing Healthcare Projects from Mold to Hyperbarics

Startups

Day 1486 and Is There A Tech Right

Day 1510 and Turning Valar On

Day 1542 and Future Blind

Day 1572 and Reskilling

Media

Day 1485 and A New Pogue at The New York Times

Day 1581 and Lecturing at UC Boulder on Renegade Futurism

Day 1569 and the sky above the port tuned to a dead channel

Day 1496 and Maneuver Warfare

Politics

Day 1484 and Montana’s Right to Compute Bill

Day 1549 and Productive Primates

Day 1578 and Dark Start or Energy Realism

Day 1576 and a NatCon Boomer Kicks a Townie Millennial Out of Their Hometown

Trends, Cultural and the Academy

Day 1484 and Zoomer Identity Violence Trend

Day 1479 and Liminal Industrial Transport in an Empty Frankfurt International Terminal Pod Hotel

Day 1580 and Learning By Doing or Embodied Learning for Humans

Day 1575 and Renegade Futurism

Day 1555 and Modern Machiavelli

And I got to about May and realized I didn’t feel like I needed to put more into the organization. I had 4 medical procedures involving surgery. My father died. My best startups all raised rounds to scale. You can find your own way from there. It’s been a hard year despite the wins.

Categories
Biohacking Chronic Disease

Day 1786 and 40 HBOT Sessions Later

The days becoming shorter has hurt my attempts at getting out in the sun for a walk every day. This matters to me as I’d like to get regular readings of my V02 maximum and my heart rate. I rushed out without sunscreen to get in a mile.

I hit an important milestone in my current biohacking regimen this week. I made it to my 40th session of hyperbaric oxygen chamber therapy or HBOT. I began on September 13th and did session 40 on November 20. I only traveled once during this period (a five day trip) so I could have fit it all in within a two month period but I was consistently doing two hours a day.

I intend to get bloodwork for comparisons next week, but in some ways this was a terribly experiment period. I had a small procedure to insert testosterone and estradiol into my left buttock which turned into a saga when I got a skin infection. Not the procedure’s fault and I’m glad I did it as my numbers are already better.

Fortunately HBOT is renowned for healing soft tissue infections so if I was going to suffer for having compromised immune health across my skin biome, then at least I had the state of the art treatment available.

We didn’t purchase the HBOT for its skin benefits. In fact, I didn’t even know I’d be have skin immunity issues. They began with my new IL-17 inhibitor which I started in January We’d acquired the HBOT around the same time but I had no idea how challenging Bimzelx would be. It could have gone worse.

We had originally acquired the HBOT as several of our friends and acquaintances had succeeded in managing impressive inflammation rate reductions as well as progress with a slew of autoimmune issues from long COVID to mold toxicity. The kind of troubles we only test in fancy labs with extreme athletes or the enterprising technology brother.

My wound has mostly healed save a small lump, my V02 max has improved despite virtually no exercise (hard to do much cardiovascular exercise with an infection in your posterior chain) and I have overall found the balance of improvement in my energy and pain to be significant.

Thanks for noticing Whoop

If I could just get a month without a health crisis where I have enough energy to workout consistently I just might make some progress. So if I disappear for a bit that will be what I’m doing. Once I’ve got bloodwork I will share obviously.

Categories
Biohacking Emotional Work

Day 1765 and Hollowed Out

I’m at home with a freaky red light mask that could absolutely pass for a horror movie prop. My husband is sealed up in a hyperbaric chamber with two atmospheres of pressure and oxygen pumped in through a mask.

It may be Halloween but neither of those activities are horror movie material even though you could easily imagine them featuring as props in a serial killer series or Final Destination.

And yet these are things we are doing for health and wellness. One man’s horror movie is another man’s idea of a good night off and you can really tell we are tired childless adults that this is our idea of winding down on a Friday night.

The childless part wasn’t entirely a choice but we picked lives of professional intensity a long time ago so Friday night spent in self care is a sign that we’ve earned some respite.

Millenial success stories involve long hours. Millennials being all hallowed out on All Hallows’ Eve shouldn’t really come as a surprise to anyone, given the current state of American politics.

I’ve never liked Halloween much as if I want to dress up I don’t need social permission and I really don’t care for parties or socializing. I got all partied out in my twenties when I had to do a ton of it for professional reasons. I know it sounds glamorous but nightlife is work.

I had a tequila client and I had a hotel with the hottest nightclub in the New York City. I somehow managed to have both Patron and Le Bain as a client in my advertising agency era, and while loved both clients it did mean eventually all I can associate with nightlife is work. When I had a night off I stayed at home and read science fiction with a face mask.

Which means some things never change. There is no suburban holiday with children to dress up and take out. And I barely have recollections of doing any of that as a child. It’s no surprise this holiday has no hold on me

I don’t know why I have no fond memories of it but I don’t. I have almost no memories of Halloween. The precious few years in which we lived in suburbs, where I had both parents and I was young enough to go trick or treating barely register. And I don’t feel sad about it

I am much sadder about the kind of world we fought to succeed in as adults. I am happy to be home and with the horror movie treatments to heal the ravages of the real world that have been enacted on both of our bodies.

The long hours over decades, the multiple Covid infections my husband suffered, my own autoimmune issues and the realities of aging are not horrors but they are real. And I acutely am aware that Halloween is pretend.

And nobody should have to pretend that they aren’t hollowed out when they are. That is a fairy tale for children and for the people who still are. Neither category include me. It’s perfectly fine to be tired on a Friday.

If I’m going to put on a mask tonight it damn well better have health benefits. Here is to red light therapy and collagen masks. May they heal what ails you on all hollows eve. You can face the dead and your demons tomorrow.

Categories
Biohacking Chronic Disease

Day 1764 and Not so Easy In and But Out of the Woods

It has been sixteen days since I confidently decided to insert testosterone pellets by tiny incision into my left buttocks. I was felt certain we’d checked all the appropriate risk factors and my tolerance threshold was met.

I felt I was making pretty decent progress on healing over five days as I had not only the benefits of HBOT but also read light therapy. I was pretty darn pleased and felt well.

And then it seemed I took a turn six days further on. Perhaps some trauma from the lidocaine and epinephrine induced enough of altered window of immunity that some bacterial weaseled its way in the wound and viola a subcutaneous infection called cellulitis.

I was put on two different antibiotics and we figured it would clear quickly. That was incorrect And it has been a slow healing process

Barely improving day by day. And I had somehow made the decision the night before the procedure that I would just waltz into a new beauty shopping blog as the holiday season warmed up. So that was perhaps bad luck on my part. And has slowed me down on something I was doing for some joy so I hope I didn’t let anyone down. I am muddling through.

Today I got an ultrasound on the wound after a fever spike and did a number of blood tests to see where my white blood cells and inflammatory markers were at.

The local hospital was having computer troubles which meant trouble scheduling an ultrasound but we managed to find another imagining clinic this morning.

Back at the hospital for bloods (they do walk ins for blood draws) they still appeared to be having issues with computers. “Your insurance isn’t recognized” was the verdict thirty minutes after using it at other lab. That made for a chuckle but we got it done.

The results are already in and we seem to be looking at healthy epithelial tissues and my CRP and Sed Rates were not elevated. Of course, half the reason I am worried is I take an immune suppressant for chronic autoimmune inflammatory condition.

It seems to manifest frequently as skin infections. My old drug wasn’t nearly as effective but it also didn’t have side effects. S

Hopefully slowly and with lots of protein and rest I’ll be healed and can spend my time on work and my pet beauty blog.

And tomorrow I’ll cross my 30th HBOT treatment mark so maybe it can make progress on building me up instead of dealing with a flesh wound. Which is actually just damned good luck on our part.

Categories
Biohacking Chronic Disease

Day 1761 and Give Me A Break

It has not been an easy year for me or my family. The struggle to find a path to a sustainable place of health feels harder than ever.

I am living in some type of thermodynamic hell. Everything I try comes with equally forceful reactions and I wish I could say more of them were positive.

Even when results look positive they have high costs that make me reconsider if I should have done it at all. Switching my immune suppression drug put my inflammatory markers in the best place we’ve seen them in years.

Alas it is so effective that I’ve had four major skin infections in 2025 of which four required going under the knife. And the fourth was caused by a small incision that was considered so safe and routine we almost didn’t consider antibiotics at all.

I just so badly want something to work in a way that doesn’t come with staggeringly high costs. Normally I’d link around to all the relevant posts but I just need a break so I’ll leave it as an exercise.

But can you imagine anything more depressing than having an infection on your ass? I sure can’t. I am stuck trying to keep pressure off of it while working on all the various projects of life and I am a slow healer.

I don’t even get to see if the HBOT is doing anything for my main concerns, as if it is we are only going to see it when I clear this crazy infection.

I suppose the good news is that one of the best treatments for high risk wound care is actually hyperbaric oxygen therapy so the positive and the negative are at least balanced.

Categories
Culture Emotional Work

Day 1760 and Optionality or Commitment Issues

As I sat inside our hyperbaric chamber for my 26th sessions of oxygen therapy, my mind was on commitment. I like a routine and a plan and being locked in on my follow through.

I don’t recall when I was introduced to the concept of optionality, but it wasn’t something I recall being raised with. Despite being raised by hippies and yuppies,who themselves struggled with commitment, I never doubted that loyalty and stick-to-it-ness were crucial personal values. I don’t like to quit.

Maybe somewhere in my 20s though it became clear that many of the people I dealt with in “the big city” always had their eye on their next move.

Maybe it was campaigns like the World Economic Forum’s infamous “You will own nothing and be happy!”

Trends slowly put the meta structure of optionality as a construct into my mind. And it wasn’t too foreign to me.

We moved a lot as a child, and I never felt like I could get too used to anything because change was such a regular part of my life. I could reconcile being committed to always changing as the balance.

So the idea of always trying to add in additional optionality struck me as a little bit funny. Why would I always be looking for the door, or looking for my next move, or the next upward opportunity, when so much of what I longed for as a child was a basic sense of stability in my own home life?

Now, of course, the idea of optionality is baked into almost everything we do. Owning things is expensive, and financial challenges made the sharing of resources and assets like homes and cars seem perfectly natural to a millennial who had barely gotten by in the Great Recession.

But now, as I watch reality television like Love is Blind, a dating show designed to result in commitment, we see so much fear.

An inability to choose a path or to consider changing the path you are on to be with another seems to plague participants the further they take the franchise. Optionality is one thing but we’ve stumbled into a world where commitment is a foreign language.

Categories
Emotional Work

Day 1759 and Who Are We After Someone’s Death?

They say you shouldn’t make any significant changes after a death in your family. Grieving is a process and allowing oneself to feel the range of emotions in loss is important.

You might not feel your grief if you jump into something new. Making a change could be hiding your grief from yourself. And so I am trying to sit with my grief.

The loss of my father on the last day of the summer was both expected and painful. As I have had to find my own way to grieving, without being part of his memorial, I thought a lot about what life going forward meant as I honored our past and let him go.

I wondered about which parts of my history and my identity gave me my life. If I wanted to make changes in my future, or to broaden my horizons, what would it look like?

How could I be sure I was being true myself in the challenges of my chosen life and true to the deep and complex relationship I had with my father. All these questions arise.

Somehow I am happy. I feel more love for myself as I see the ways I tried to love my father, and how he tried to love me as his child.

Being who we are, means seeing the child in ourselves who wanted to be loved for who they were, while learning as an adult that acceptance is up to us, not the generation who birthed us. The liberation of birth anew.

I hope the many experiments I’ve run with my biohacking over the last two months are helping me stay in my body during this process. I am on my 25th hyperbaric chamber oxygen therapy treatment today. Which is fortunate as I am healing yet another skin issue as I try to find ways to have the strength to be myself in my very challenging body.

And so I wonder, am I the same without my father as I was with him? I am always searching for ways to become better, stronger, more informed, more capable, more successful and ultimately I fear those are all synonymous with finding ways to be more lovable to him? I couldn’t always tell.

I’ve found myself wishing to indulge a past professional calling with a side project. I’ve been writing a beauty shopping column where I go deep on my autistic special interest in skincare and the business of appearances. It’s been making me happy.

I have even decided make a special offer founding members who join my first year as I wish share some of my own happy knowledge. For a nominal fee I’ll build a routine from my cosmetics library and decant and organize the perfect skincare routine optimized exactly for the life you are living.

And so I ask does this count as a change? Am I jumping into something new, even if it is small, too soon?

All I know is that it feels right and like a joyful offering, even if there are parts of me that hurt. Perhaps there is a good kind of change to be had in endings with new beginnings. A personal passion once put aside, reemerges to serve others.

I think that is something my father would have liked to see me do. I have pursued so many of the things I know he wanted for me in this life. I do have a future full of technical change and a portfolio focused on the future of computing.

And yet here I am feeling freed to show that some aspect of who I am as a woman does want to serve others. If it is in the cause of helping be comfortably in your own skin that seems rather a positive thing to become after this life change.