Author: Julie

Categories
Biohacking Chronic Disease

Day 1491 and Snappy

I am a bit snappy at the moment. Everything hurts and too much is happening. Despite my endless horizon of opportunity my circumstances tightens to the pinprick focal point of pain.

Once you get angry enough that you quote Kierkegaard in public settings it’s probably a sign to knock it off.

I don’t have much of utility to say here except any problem that comes down to information acquisition is an excellent opportunity to make use of new tools so both myself and my husband have been deep in model comparison of different reasoning chains as we try to untangle IL-17 inhibitors vs 23.

It’s a weird feeling to be watching the crisis of institutional confidence in medicine play out over the most incredible extension of knowledge and capacity in my lifetime. PubMed spelunking? Pffft nah we got Sherlock Holmes mode for free.

Categories
Chronic Disease Politics

Day 1490 and Healthcare’s Sin Eaters

I went to see a rheumatologist today. I had the baffling experience of them wanting to actually get to know me. Which was surprisingly unhelpful in the moment but really nails vibe we’ve got with healthcare in America.

I kvetched on Twitter that I spent my week defending hot girls and open source software while I deride Big Pharma and public employee unions. That’s more of a humble brag about my priorities. But I felt bad that I picked on pharmaceuticals. I got replies. Why harsh on pharmaceuticals? And actually fair.

Drug companies are the least bad of some very bad actors. For all its faults, drug companies are not just existing to be parasitic like pharmacy benefit managers or generate wealth through regulatory capture like Epic.

If anything pharma is the sad scapegoat in healthcare. We pick one drug a decade to laud & then like clockwork do a hard reversal on it in a decade or two. Patients get hurt and doctors did their best. We saw with statins, SSRIs, opioids, adderall, and I’m sure soon GLP-1s will be next to have Netflix documentaries. Someone is always to blame and it’s usually the drug companies.

Some category is designated a sin eater for the system’s horrors. Which isn’t at all fair as all those drugs serve real needs. Sorry Oxycodone you remain a villain. But why is American in so much pain?

Which gets back to my surprise as having a doctor who wanted to get to know me. We came in with a typed up diagnostics sheet with a timeline of treatments, protocols and medications and the bastard has the audacity to ask me about the quality of my life.

I hesitate to say “well shit” because I am Protestant from Scandinavians stock because we pride ourselves on being “oh just fine”

And of course I’m the asshole who quotes Kierkegaard at my doctor. Sickness unto death right Doctor? Which I guess is a bit of a downer.

The man actually asked me if I’d consider managing my pain more aggressively. I am absolutely mogged by the audacity of the sentiment that I could suffer less.

Apparently no one scans you for drug seeking behavior when you chuckle and kneel before what God has decided for you. So that’s a good trick I guess for the less sincere.

You can really see how public perception of RFK Jr is so different from what elite narratives would like to see. People are with RFK’s righteous indignation. Why are so many suffering?

The cranks and the crazies are here because America is mostly gaslit by a nest of bad incentives. Doctors don’t want any of this. Neither do the drug companies. But someone has to be blamed and it’s usually the guys with the money. But they are trying as hard as anyone to actually come up with solutions.

Maybe no one deserves to have a righteous Kennedy come after them. But everyone feels a little bit crazy with how the system works now.

Categories
Media Politics Preparedness

Day 1489 and Foggy Frosty

I felt it was very important to get off the internet and soak in some restorative aesthetics. We are in a shock and awe moment almost anywhere you look from national politics to geopolitical technology competition. And everyone is jangling for narrative.

We’ve been a fog of informational war so long we forget we are all subject of multiple intersecting and independent actors who want your attention to be on their issues and their terms. We are living in context collapse hell.

Ans it’s not going to get any better. Many independent minded citizens are arising in these challenging times and they all operate with mindful caution. We have to invent our way out of the most challenging information environment of our lives.

Americans don’t realize we are subject to political and industrial competition and it plays out across social media. Don’t think because you know it is being done that you aren’t heavily affected. America has foreign enemies and quite a few domestic ones.

Extremism exist in some very weird bubbles. I am concerned seeing rationalist singularity cultists. But I’m also concerned about high frequency hedge funders who manipulate markets. We are in a great power competition and I’m sure we all have totally sensible opinions about open source artificial intelligence models. Right?

It’s all very cyperpunk. Manipulation of financial markets is as grey zone a tactic as sniping the telecoms pipeline from Helsinki to Tallinn. And we should be concerned about being competitive. We’ve been snowblind before

It’s a nuisance as neither you nor I have a clear line of view. Some of us maybe have a few months heads up. The lead feels less and less even as I am as much a part of shaping narratives as anyone. I was using DeepSeek in the fall.

When I was in fashion we had this website called “don’t believe the hypebeast” to mog those overly concerned with cool. Don’t get mogged. The same principle applies here. Don’t try to figure it all out.

Go read something with soul, listen to some Bach, and be with your family. Be frosty in the fog and exist in the real while you still can.

Categories
Aesthetics Biohacking

Day 1488 and Tune Ups

The back half of 2024 was such a whirlwind I keep discovering new eras where I am behind on keeping the engines of my life tuned.

While I’m adding in new excitement to my healthcare like hyperbaric chamber oxygen therapy (in the market to acquire one for my own use if you have recommendations) I’ve still got to make the various rounds for everything from my general practitioner to my osteopath to my dermatologist.

If the world is going to insist on going at this pace and I’m unwilling to slow down (because why would I?) then it’s full speed ahead on regular time ups and maintenance.

I hadn’t been to my osteopath since August. I hadn’t been in for Botox since October. And apparently I’ve not had a haircut since July.

Yes some of these are a bit more cosmetic than health driven but I’m somewhere closer to an old Mercedes than the family Subaru when it comes to appreciating form and function.

Categories
Internet Culture Politics Startups

Day 1487 and Gell Mann Amnesia

It’s a busy day for competitive narratives on social media (and in the markets) as normies are belated reacting to news about a new open source artificial intelligence model from a Chinese quantitative hedge fund called DeepSeek.

The new model been available since Wednesday though many of us open source fans have been using prior versions for quite some time.

DeepSeek even powers the skincare bot my friend Kasra and I have been playing with for fun. We used all the open source models We are early days and hyperscalers have different games they play than us tinkerer types.

I have no hot takes for you on what it means geopolitically or otherwise. You can doomscroll for Jevons Paradox, the possibility of a Sputnik moment for the West, and the benefits of constraints for creativity.

What I think is most useful to remember about media narratives is the Gell-Mann Amnesia effect. Coined by Michael Crichton of Jurassic Park fame it helps remind experts to not expect expertise from normal people.

Briefly stated, the Gell-Mann Amnesia effect is as follows. You open the newspaper to an article on some subject you know well. In Murray’s case, physics. In mine, show business. You read the article and see the journalist has absolutely no understanding of either the facts or the issues. Often, the article is so wrong it actually presents the story backward—reversing cause and effect. I call these the “wet streets cause rain” stories. Paper’s full of them.


In any case, you read with exasperation or amusement the multiple errors in a story, and then turn the page to national or international affairs, and read as if the rest of the newspaper was somehow more accurate about Palestine than the baloney you just read. You turn the page, and forget what you know.

Michael Crichton

I am passionate about the right to compute because new technologies should not be in the hands of only giant corporations or controlled by nation states.

Most of the commentary you will see on any given topic of media interest will be a fog of war mismash of competing narratives and ambitions.

Just remember that it’s wise to be wary of any certainty when it comes to what’s going on. What we know changes on what we know and it’s odd how easily we forget that.

Categories
Chronic Disease Politics

Day 1486 and Odds and Ends and Migraines

It was a busy week. I felt physically well through most of it, but yesterday and today I am struggling. I’m in bed with a migraine that I think I accidentally kicked off by enjoying a quiet walk on sunny snowpack.

Amusing that people think we don’t get enough sun for solar power

While I prefer to have illness strike on a weekend, I feel irritated that I often get my personal time used up by health issues. I very much prioritize using my good hours for work.

Which on that note, I’d love for folks to check out a bill in Montana to secure a right to compute. What started as an idea has now officially been introduced into the legislative process. It’s a big victory to have this under consideration.

I was also in the New York Times this week in a column by James Pogue. It’s my second time being interviewed by him and I think quite highly of his reporting.

A few quotes in the New York Times on the tech right, the H1B debate, and a general sense of getting back to business

Categories
Media Politics Startups

Day 1485 and A New Pogue on Technology

The paper of record just doesn’t know what to make of a political constituency that it has been determined to view as a billionaire bad boys club. And so after almost a decade of hostility between media and Silicon Valley, it is clear the vibe shift has come in the house style at the New York Times as it is dedicating a lot of ink to “Tech Right” and how it views the world.

A new narrative of technology is emerging. Veterans like Maureen Dowd alternate between mean jabs and fawning over “the high school oligarchy.” Ezra Klein’s podcast this week worries over tech’s relationship to Trump 2.0.. The right leaning institutionalist Ross Douthat interviewed Marc Andreessen on how Silicon Valley came to leave the Democratic Party.

The editors appear to sense the shift of power. And with new beats come new talent. The Grey Lady has hired an opinion columnist James Pogue who actually does reporting with these elusive new right and tech right figures.

Old timer readers might appreciate that this new talent shares a name with a past technology columnist. Pogue. David Pogue reviewed gadgets from 2000 to 2013.

Despite being millennial, James Pogue is an old school reporter. His popularity derives from his deep reporting. He picks up the phone and talks to people. He shows up to events and reports on what he sees. He does it with verve and style but lets his subjects speak for themselves.

James Pogue’s author photo

James is having something of a moment judging both by my group chats and the most shared analytics. Not only is his New York Times opinion column going gangbusters but he is also going viral for his long form gonzo essays in Vanity Fair.

If you enjoy learning how the media sausage gets made Isaac Simpson has an interview with James Pogue on his newfound status, his reporting style and how he ended up at the center of the political and cultural moment.

It is here I do full disclosure myself and say I’ve been interviewed by him twice and we have social relationship that includes being on a very similar professional and social circuit. Because he actually goes to report on things in person we’ve seen a lot of each other over the years. A reporter grows with their beat.

If you are interested in what establishment media has to say about this new power base of new right, tech right and a rising counter cultural elite and prefer your news to be deeply reported then make yourself familiar with James Pogue and his work.

He has a nuanced understanding of the personalities, always his homework, and incredible access to his sources. I guess this is what happens when you ask questions and then let your subjects speak for themselves. If anyone has the secret to the media rebuilding its trust with readers my money is on James Pogue.

Categories
Internet Culture Politics

Day 1484 and Montana’s Right to Compute Bill

The one thing that really unites the American west, but in particular the Rocky Mountain West, is our independent streak. We take our rights seriously.

We don’t like being told what to do by the government. I hope to contribute to this tradition in my own efforts as a citizen. I’m pleased to support a bill that guarantees Montanan’s right to compute.

It shouldn’t be up to the government how you decide to access compute or what you do with it. Don’t be fooled by jargon or think tanks with fancy experts, computing is just math. We must secure our freedom to compute and Montana is leading the pack on this issue.

So what does this bill do? I’m cribbing a Tweet from Tanner Avery with a terrific synopsis but you can read the full bill here when you’ve got extra time.

Sen. Daniel Zolnikov has officially introduced SB 212, the Right To Compute Act, to the #mtleg.

This bill will ensure Montanans’ rights to free expression and property are protected in the 21st century, in addition to helping position Montana as a world-class destination for AI and Data Center investment.

Here’s what it does:

1: Establish the Right to Compute: The legislature makes it clear that privately owning or making use of computational technologies for lawful purposes is protected as an aspect of fundamental rights to free expression and use of property.

2: Create a New Policy Framework: Restrictions on the ability to privately own or use computational resources must be limited to those demonstrably necessary and narrowly tailored to fulfill a compelling state interest in public health or safety.

3: Balance Interests: Provides mechanisms for policymakers to address real harms to public health and safety posed by the application of new computational technologies, while also ensuring that regulations do not excessively burden the Right to Compute.

I feel like I’ve been discussing this issue forever but in reality we are in the first innings of how artificial intelligence will change our lives. And it has real possibilities for making many aspects of our very human lives better.

I don’t want this technology (which is again just math) being restricted by the federal government or dominated by a handful of corporate behemoths who can comply with endless regulations. Compute is for the people.

The last best place to compute
Categories
Biohacking Chronic Disease Medical

Day 1483 and Trending Up

I let myself get a little shook up by some poor health news early in the month. I’ve been pushing it physically all through 2024 as let’s be real it’s an exciting time. To fully capitalize on that acceleration we are all more focused on improving our health.

I’m taking action and optimistic about where we are headed with improvements in healthcare. I was able to rapidly iterate through options and set up surprisingly effective new treatments.

As we’ve work through the significant impact of the pandemic on our understanding of post viral illness and autoimmunity, we’ve had a more systems driven approach to testing interventions beyond pharmaceuticals reach more people.

Not that all pharmaceutical interventions are bad obviously as I’m lucky to have interleukin inhibitors in my life. I was able to find a new option with my doctor thanks to help from Claude and Perplexity.

And this progress is happening across all areas of medicine. I am also incredibly bullish on the benefits of GLP-1 inhibitors and their next generations. Inflammation and metabolism are intertwined in ways we can control barely articulate beyond “mind body connection” and yet we are developing the vocabulary.

I enjoy strange adventures in the future now. I am going to be experimenting on my body as it helps me understand not only myself but the evolving opportunities in investing. Even science fiction is excited about biotechnology.

The problems I am solving for myself teach me how we will allocate resources across many industries. The energy required to power artificial intelligence and the chips required to run those models will be pulled forward by our desire for solutions to living healthy lives

Categories
Aesthetics Internet Culture Preparedness

Day 1483 and If You Die In The Matrix

Twitter has become an unmonitored Wild West of content. This is mostly good for those of us looking to understand the world “as it is” and not as we wish it to be, but requires a certain cognitive security not everyone is prepared to engage in. What was once kept to the dark corners of 4Chan splutters up.

We witness more violence than we did during its “trust and safety” years. Thanks to algorithmic chaos quite a bit of gore, pornography and death will regularly hit main feeds.

A friend of mine (whose line of work would put her in a position to know) has a theory that Zoomers will cross into physical world violence more easily than past generations. We have long debated as to why and how it will manifest but it’s already begun.

Being raised in digital always- online mobile environments means their reality is more malleable. And yes the internet is real life. We live, we love, we hate, we play and we work online. But what of violence? Are we prepared for that crossover?

Digital life has given them an immense sense of freedom to act without consequences because the virtual world is still sequestered from some consequences. And unlike millennials, whose sense of The Real and the Matrix, was anchored by a physical consensus reality, I’m not convinced this will be true for all Zoomers.

If you die in the Matrix you die in real life

We have already seen the maturation of bringing Internet identities to our regular life physical world. Violence has always been there lurking, but it is now bursting forth and I believe it will only become more prevalent.

Today I read news stories of two separate incidents of violence that I can only read as Zoomer Internet Identity Violence. Be warned they are both upsetting and confusing for non-internet natives.

A German math Olympiad transwoman on an H1B visa was killed in a shootout with a border patrol agent in Vermont. A shooting in Nashville involved a full Google document FAQ on a flavor of soyjack I didn’t even know existed and will not type here.

If you die in the real world perhaps you live on in the Matrix of the infinite internet. But this is not an end that we should wish for our civilization or for our Zoomers. Be prepared to see more of this.