Tag: Extremely Online

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Biohacking Finance Internet Culture Medical Startups

Day 350 and Web3 Healthcare

Imagine you’ve got a disease with a clear biomarker. I’ve got an autoimmune condition called ankylosing spondylitis. One of the ways to spot it on a blood test is to look for an elevated CRP or sed rate.

Maybe I want to find a way to connect with other patients. I provide proof of biomarker to join an autoimmune discord just like you provide proof of ownership of an NFT like they do in the Bored Ape Yacht Club. Maybe I want to join a group of other patients who are pooling their medical data so they can stop being in an N of 1 and have a chance to participate in new research for my own disease. I could join AutoimmuneDAO and contribute to funding, meme-ing, and researching my condition. If we discover a treatment protocol or drug through our DAO we’d have ownership in it. Imagine a token for your own patient DAO. This isn’t as crazy as it sounds. VitaDAO is doing this for longevity research. This is the future that web3 can bring to healthcare.

Quantified self and biohacking have improved my health significantly. But on its own my personal health data has little value. You would maybe pay me a few cents for my biometrics. The real value of that data is in the aggregate. That’s why I pay Whoop to manage my HRV data and why they won’t offer data interoperability.

The value is in the algorithm. But without me and without my data it wouldn’t be worth anything. They have a product and an algorithm because of my biometrics. And yet we’ve found no way to meaningfully integrate ownership and interoperability in healthcare yet.

Let me give an an example. There are multiple companies that make their money by recruiting clinical trial candidates. Why? Because you need aggregate data to run a study. Those companies have the same basic data analytic team as a marketing team at a direct to consumer product company. They know how much a patient (or customer) is worth and the cost to acquire them. You are worth a lot because you represent a demographic that has value in its totality. And yet most clinical trials fail to recruit people because patients just don’t see a benefit to participating. You’ve got no ownership or upside and the costs are significant. So science suffers.

But what if instead of being valuable to marketing and recruiters you could own a portion of the aggregate? Being a token holding biomarker “proof of disease” validated member of a patient research DAO flips the incentives. A breakthrough on a disease that treats you and you’d also own some of the proceeds of it’s intellectual property. Whoever brings web3 to healthcare is going to be doing a significant good for humanity. Web3 can improve diseases, move forward science and get us all paid.

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Finance Startups

Day 348 and Empathic Investing

The best investor I know is Cyan Banister. When I was coming up in the web2 world I got to watch how Cyan handled early stage relationships. She brought total empathy to every interaction I witnessed. The kind of candor, kindness and willingness help her founders eventually set the template for how I wanted to work. I wanted to invest with my whole self like Cyan.

While I doubt it was the primary motivation or even expected outcome, Cyan’s angel investments are some of the best returning of the generation. If you subscribe to Alex Danco’s theory of social capital and angel investing this kind of investing is playing an infinite game. It clicked for me then that the real edge you can bring to the earliest stages of startups is an open heart. An open heart gives you an open mind. And everything else is a matter of tactics from there.

Creativity comes from seeing something in a completely new light. A change in metaphor can lead to tangible physical discoveries and complete cultural revolutions. Science fiction gave us the tricoder and the internet. Imagination literally helps forge the future. So it’s important if you want to spot the catalyzing “this changed everything” moments that you be open to seeing the world in an entirely new light.

While I obviously have an investment thesis on the macro level events shaping market demands, it’s not practically nearly as helpful in the day to day of investing as just being human. Creation is volatility. It’s not usual for a founder to bounce between terror and euphoria on the same day. Imagine how exhausting that can be when your entire life is always fight or flight and fear or famine.

My only job is to show up for a founder in that moment and accept them for who they are. They need to trust me enough to tell me if they are scared. Trust me enough to share their biggest wildest dreams. It’s a delicate and intimate thing to be there for someone no matter what. But I firmly believe that is what it takes to build something worthwhile. It’s never ever clear from the outset if it will succeed. The only thing we can truly have confidence in is our ability to solve the problems along the way. Chances we’ve seen the tactical playbook and can help you solve those more easily. Many of us come with baked-in operator skills like acquisition or operations. We can teach you that.

While this may all sound utopian, or if you are a bit cynical, even maudlin I assure you this is the most competitive way you can approach investing. If capital is simply a commodity you must infuse your work with real value to compete. If you have a lot of assets under management maybe you can add a lot of services. Large prestige funds with billions in AUM can offer that. But now you have to have bigger deals and surer outcomes so that impacts what you can invest in. Scale impacts outcome in all kinds of practical ways.

If it’s all about the capital then you can be beaten not just by a better term sheet (which just makes everything you do more expensive) but also by someone who brings intangibles to their place on the cap table. You know whose pro-rata doesn’t get cut? The person who showed up day in and day out before the round got competitive and every is kissing ass to get in. The founder remembers. And so does the empathetic capital. We win twice over because our deals are cheaper and we stay in them longer.

So founders and fellow investors ask yourself who you want in your corner from the start. You may find the smartest capital is actually the nicest capital as well.

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Biohacking Medical

Day 341 and Drugs are Good M’Kay

I am a prolific consumer of supplements and vitamins. I maintain a spreadsheet to keep track of all my inputs. I take a bunch of exotic stuff so it’s easiest to check for interactions and assess impact if I maintain strict consistency.

I’ve seen remarkable benefits to the entire mess but it’s taken over a year of dedication to see the compounding effects. Taking vitamins isn’t quite like taking a pharmaceutical that way. But I suppose everything is dependent on dose. And yet I tend to apply a completely different moral valence to my supplements then my pharmaceuticals.

When I was a teenager it felt like the war on drugs had mostly devolved into scar tactics. After school specials, assemblies with terrifying speakers, and the general media landscape showing “this is your brain on drugs” probably gave me an unnecessarily limited view of how to approach drugs. Recreational drugs were bad but I also knew that pain medications were deadly. It didn’t help I had a family member who was an opioid addict.

The running gag on South Park with Mr. Mackey telling the kids that drugs are bad mmm kay logged into my subconscious. And not in a sun skeptical way. I appear to have taken it at face value.

South Park’s Mr Mackey says drugs are bad…mkay?

Except drugs are neither bad or good. I wouldn’t dream of considering my various supplements and vitamins as making me bad or weak. Those keep me healthy and function. I also take prescription medications. Those also keep me healthy and functional. It’s the same thing. I don’t take them for kicks or to get high.

But the idea I absorbed from childhood that I’m supposed to regard things like pain killers with intense skepticism continues to hinder my progress. I was warned by the orthopedist I may need to up the anti-inflammatories I take for my spine as my ligament injury heals. But I am still reluctant to take the prescribed dose. Despite being under the supervision of two doctors.

I’ve got to learn to let go of this attitude. Drugs are good mmmkay? Tinkering and tweaking and looking for improvements are great. No one deserves to be in pain. It’s not morally better no matter what religious nonsense we may have absorbed. Sure pain is a terrific teacher. But it’s perfectly alright to chose to forgo it. We can chose to grow without inflicting any more pain on ourselves than necessary.

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Aesthetics Preparedness

Day 339 and Doomer Optimism

I write a mini-festo for the Doomer Optimism community. I am sharing it here today as well as gosh darn it I wrote it so it counts.

I come from hippie utopian stock. My parents, both working class union types, moved us to the promised land of Silicon Valley right before I was born. The family lore concludes that my father had no job on the day I came into the world as he was pitching a startup. My parents believed in the promise of computing, and eventually, the internet, to connect free thinking humans in a culture of collaboration and self-sufficiency. The do-it-yourself ethos of Stewart Brand’s Whole Earth Catalog combined with a heady blend of technical opportunity and growth that is well chronicled in What The Dormouse Said. This gives you a sense of cultural milieu in which I was raised. The sixties had long given way to the Reagan revolution and the rise of Clinton’s neoliberalism when I came on the scene, but I never forgot my roots. I invest in startups to continue that legacy of autonomy and freedom at my own fund chaotic.capital.

“Remember what the dormouse said: feed your head.”

For me doomer optimism is the continued braiding of those cultural strands. Each one of us is capable of connecting to each other and enabling ourselves, individually and collectively, to lead the life of flourishing and growth we seek. We want tools and information that feed our head but also crucially our heart. The key insight that these very different culture strains, hippie and technology, have shown us, is that individual empowerment is what ultimately connects us to our tribes. 

How does it work? Well, natural law is pretty simple. The laws of thermodynamics are clear.  “If you do not fuck around, you never find out.” As we cede autonomy to others, we cede our capacity to fuck around. The inexorable logic of that, means we also cede our capacity to find out. Without the natural chaos of energetic entropy pushing man against nature, we get stuck. We stagnate in the local maxima. 

And we long to find out. We want to find our communities, our families, our capacities, and our passions. That is how we build. That is how we invent. That is how we solve our problems. Humans are capable of huge creative leaps. Massive shifts in capacity have risen in a blink of an eye. We can solve our problems, and indeed have been doing so, for millennia. But the only way we do is if we fuck around. Otherwise we will never find out what we are capable of overcoming. No matter how dire our problems we can rely on the deep laws of energy. So don’t be afraid, go and fuck around. We are counting on you to find out.

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Media Politics

Day 331 and No Going Back

We were never getting rid of the downstream effects of the pandemic. All the joking about the “before times” was just our collective psyche exhibiting normalcy bias. There is no going back. Inequality is rising and people are struggling and attitudes have ossified. Not because of some bizarre conspiracy but because you can’t put toothpaste back in the tube.

Every restriction and panic is just another day where the world gets more unfair and the prepared and the wealthy have more moves than those at the bottom. And so more people suffer and the gyre widens.

The thing about being privileged is that it compounds over time. Every instance of success and every lucky break build on each other. The math is an inexorable process that leads to one conclusion. The rich get richer.

The reverse is true too. Every barrier, every bill, every setback, every issue compounds too. An object in motion stays in motion.

If this all seems very unfair, I regret to say there is absolutely nothing any individual can do about the physics of success. The best you can do is try to bring others up with you. Educate them on the logic of success and arm them so they can begin to compound their own.

You can’t do it at mass scale. Individual outliers will distort every set of rules and every game within a handful of moves and the accretion of influence begins anew. There is no such thing as revolution. There is only hoping you can enable enough people to change the direction for good. That enough people chose collectively to make better choices for each other.

Anyone who preaches anything other than individuals aiding each other in freedom will have to acknowledge that all systems are prone to corruption and self serving. There is no level playing field.

Some of us just have enough ego to think if it is our people and our tribe or our political party in charge we’d do it better. That’s a lovely lie and history is riddled with the graves of societies that fell to egos of Caesars and strong men. Humans wouldn’t be interesting without our sins. We have to chose to overcome them and accept responsibility for their consequences rather than put our problems at the feet of elites.

And this unfortunate logic can lead one of two ways for America. We can either accept the personal freedom and self responsibility of each other. Or we can get smaller as a nation. What’s more likely to happen is the inequality widens. The rich and productive will write their own destiny. They will take advantage of the sifting sands. New fortunes will be built on pandemic logic and technology.

And the insecurity of the chaos will erode the positions of most fragile members of society and they will fall further as we climb higher. We will force rules on them we don’t abide by. Masks, testing, vaccines, restrictions of movement become for thee but not for me. We will restrict their capacity because it doesn’t affect our lives. It’s corrosive and unequal and cruel. It’s entirely without empathy. And we are accepting that because our stars are rising. The money is being made off this societal transition. It’s already in motion.

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Chronic Disease Emotional Work

Day 330 and Vitamin Not Pill

I was reading a fellow investor’s thesis page and noticed one lens they use for investing is whether a product is a “vitamin or a pill” with the insinuation that pills are inherently better investments than vitamins, as one is a nice to have for a business and the other is a must have. Now I can’t speak to this as an investment thesis, though I largely agree, but I do disagree on a wellness basis.

Preventative medicine is just as necessary as interventional medicine. In some cases more so, as getting ahead of a disease’s inflection point should be the humane way we handle our medical needs. We are just often too focused on short term impacts to see the value of solutions that build over time. Think of it as the quarterly reports of healthcare. Why build for the future when the market judges by each 10K?

The nature of panic may make us inclined to spend heavily on something that has become acute. But that does not make it inherently more effective or worthwhile. It’s just the immediately necessary. It just means we need higher minimum effective doses to see a result.

What we often ignore is compounding effects of wellness interventions are far superior to the mitigation of a pharmaceutical over time. Most of us would prefer to not require the costly (both biologically and financially) medicines that keep us together. This is not to say that I am not deeply grateful for all the drugs I take. But rather that I have seen incredible value in what we deem “lifestyle interventions” and other “nice to have” vitamin style supplements and protocols.

And while it takes much longer to see their effects, the compounding positive effects often wildly outperform anything that might be dubbed a pill. The trouble probably boils down to switching costs and time to pay off. Which is why an investor would prefer a pill to a vitamin. But just because something has a longer lifecycle doesn’t make it inherently less sticky. Or less effective. Or crucially any less profitable. The only way we ever see the deeply positive effects of habitual practice and dedication is to do the work. That work is boring, repetitive and low payoff. Until, most times years in the making, you see how putting your future self over your present self is what is giving you the future you always dreamed would be yours.

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Emotional Work

Day 329 and Thanksgiving

I have so much to be thankful for this year. I don’t have a lot of poetic thoughts on it, though I have written extensively about my feelings on some of the bigger moments of the year. So click those if you want essays as this is going to be mostly a list.

I’m grateful to have recovered my health in 2021. I’m equally grateful I had the money, support and willpower to achieve it.

I’m grateful I have a husband who understands me and gives me the love, support and freedom to be me.

I’m grateful for having a space to share my thoughts daily, and rather than be punished for speaking my mind, I am rewarded for it. That includes WordPress, Twitter and all the people who made the internet possible.

I’m grateful I can live in Colorado and still do the same work I previously thought I would only do in New York or San Francisco.

I’m grateful my mother sent me to Waldorf school. I’m grateful I have a father who supported my development as a full human being.

I’m grateful I can afford to buy whatever dumb shit I like for my hobbies which range from expensive skincare to preparedness.

I’m grateful I can consider buying a home that will have the capacity to provide safety even as the world around me has risks.

I’m grateful to have business partners who share my vision for investing and founders and entrepreneurs who allow me to help them.

I’m grateful I never have to worry if there is enough money in the bank to buy a book.

I’m grateful that the supply chains have held so that I have an apple pie that I ordered online the day before the biggest holiday of the year which I picked up in my car that I was able to buy even as global trade was strained and our currency was inflated.

I’m grateful for the time to pursue emotional capacity and the money to pay for it.

I’m grateful for chemistry and the wide variety of pharmaceuticals and supplements that I take every day.

I’m grateful for my iPhone, it’s applications and games I use daily on it that have connected me to a world of people virtually that I love as truly as the people I interact with physically.

I’m grateful for shitposting.

I’m grateful William Gibson still writes. And I’m grateful that Twitter has let me interact with my favorite writers.

I’m grateful for West End BBQ and Spruce Confections.

I’m grateful for my raw milk dairy cooperative and it’s farmer Daphne.

I’m grateful for sunscreen and for apple cider vinegar.

I’m grateful for Costco.

I’m grateful for my parents making good decisions when I was younger that have compounded into incredible luck and prosperity for me.

I’m grateful to be American and I’d like that to remain a thing for which I am grateful.

I’m grateful for democracy, the enlightenment, free elections, a free press and liberalism.

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Internet Culture Politics

Day 326 and The Long Now

A culture lacking optimism is a culture without a future. Even before the pandemic, American youth had plenty of reasons to temper their optimism. Inequality, corporate dominance, rising debt particularly for school, unaffordable housing, lack of social support for family, the changing climate and the frequency of natural disasters all tend to weigh on you.

I’m a optimistic person so I always presumed I’d find a way around things. And I largely did. I got an education. I started my own company. I sold it. I found I had developed a valuable skill set. I met a man through one of my best friends and we got married. All was well in my American dream for many years.

But cracks had always been there. Little details that made me question common cultural, social and political assumptions. I discovered the limits of modern medicine with a chronic disease. I saw the disaster that financialization could wreck on families with a bankruptcy. I wasn’t naive about our systems and their inequalities.

But the knowledge that the future could be worse than today wears on you. Once you start living in a liminal state it gets worse. The pandemic made it harder for me to believe in the future because the present became a holding pattern. Ben Hunt at Epsilon Theory calls this The Long Now.

The more we put off investing in a future the more the long now stretches on. We borrow against all the things that could build us a better tomorrow. And we fall back. We put off doing things that would make our future better because it’s rational to do so. What if things get worse?

I’m tired of living in the long now. I’m investing in myself. I have been investing in my body and my health. And I’m ready to invest in a home. Not because I particularly want to own property but because I want to stop the long now and believe that my future is something I can build.

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Chronicle Internet Culture Startups

Day 321 and Distracted

I was so excited for today. For the first day in weeks I didn’t have a single appointment on my calendar. I had finally run the gauntlet of bullshit obligations that has been chopping up my focus and my days.

I went to bed last night sure that’s I’d finally send out all the emails to folks I wanted as limited partners in my fund, follow up with a bunch of founders, and organize all the various materials and research just waiting to be published. I was going to make progress! I was going to pull the future forward with my own willpower.

But what did I do instead today? I sat in on DAO governance calls in Discord. I accepted an invite to a new working group for a stateless crypto project that is being rebooted for its second round. I listened to token and ecosystem rooms on Twitter for projects I’m invested in. I watched some bitcoin maxis fight against some side chain projects. And I read a bunch of newsletters and financial papers. Which all sounds productive but is basically me just fucking off.

The future arrives whether I pull it in on my force or will or not. Distraction probably has no meaning. But I did finally find a house in Colorado that I could see myself buying. So the only appointment on the calendar tomorrow is visiting the property. So perhaps that’s as much progress as was necessary.

Categories
Finance Preparedness Startups

Day 320 and Chaotic Families

I’m fundraising for a seed stage venture capital rolling fund chaotic.capital. Since this is a blog for my friends if you are an accredited investor I’d love for you wander on over to take a looksy. Or feel free to send me a DM on Twitter or slide into my email inbox which is julie AT chaotic dot capital. The TL:DR on the fund is that the world is getting exponentially more complex and that is making living life chaotic as fuck.

Humans don’t like chaotic. We like predictable. So we invest in seed stage technology startups that help individuals, families, organizations, and even whole communities, adapt to living with in a more chaotic world. I’m talking about all the areas we invest in on the blog. Yesterday I mused about chaotic labor markets and what kinds of companies are exciting to us there.

Today’s post is about about how families might adapt to a more chaotic world and who might capitalize on the future of adaptable families. Millenials aren’t having children. Maybe because they know our current systems aren’t set up to support working parents and their children they decided it wasn’t feasible. We need to fix this if we want to have a future.

Millennials lack the familial and community ties of previous generations and they dislike that they have been saddled with increased housing & education costs while having fewer resources to invest in having families and homes. I wouldn’t be surprised if we see a resurgence of planned communities and kibbutz style housing. HomesteadDAO or KibbutzDAO could emerge as collaborative non-corporate structures for new planned communities. Or get wild and maybe we see baby DAOs with multiple parents legally bound to one child. For all you Expanse fans I would be open to raising a Jim Holden on a Montana homestead with you. Only kinda joking.

Practically though the only way we solve for a better future for families is by giving individuals the flexibility they need across all facets of their life so we can adapt families to the future.

We need to support families where they live, where they educate themselves & their children, where they source & prepare food, where they need medicine & healthcare, and even where they find partners. There is a lot more private industry and startups can to support families profitably. The more flexibility we can grant people in building their ideal family unit the better. If one variable changes then every variable changes. That’s where startups excel generally. Software can expand the set of services available to people.

Because we’ve got a social structure problem with capitalism right now. Families aren’t affordable. Maybe we see alternative housing and family structures become increasingly appealing as the nuclear family structure cannot not afford a family. We may see living arrangements that let multiple families come together to provide childcare, food, education communal support. Whatever solutions come up we need to consider them.

Or we find ways to let families come back together. Increasing rural broadband and support for remote work could allow kids to move back to their hometowns to be near parents and grandparent to give us a chance to knit back together communities and combat urban isolation. The more we can improve opportunities in rural towns where existing family lives the more opportunities we create. That means we will need to provide all the services we expect in a city but remotely. Software businesses to the rescue! Here is an incomplete and in no particular order list of startups I would consider funding.

Request for Startups.

  • School contract swaps for private schools to allow easy mid year transitions or voucher searches for public schools
  • Teacher & childcare marketplaces, swaps or even parent run DAOs (bounty for 7th grade science teacher for homesteadDAO anyone?)
  • Home care shares & swaps or marketplaces (elder & children)
  • Remote healthcare providers & their tech stack particular support for specialties, pharmacy & data products
  • Fractional housing, co housing & house shares or other communal living for families
  • HomesteadDAO, KibbutzDAO, TownDAOs, Mobile & Van Life DAOs
  • Rural broadband services
  • Direct to consumer farm access to enable food supply outside of supermarkets & hubs
  • Any & all remote work & collaboration SaaS products & training to move more jobs out of urban hubs.
  • Fertility or birthing DAOs and co-parenting legal constructs for multiple parents