Categories
Aesthetics Politics

Day 1303 and Toaster F*ckers

If you are someone with a gentle constitution who finds vulgar language or discussions sexual appetites upsetting, this post won’t be for you. I doubt readers like this as one of my most viral pieces was titled“dickriding” but just in case you’ve been warned. I’ll be discussing the toaster fucking problem today.

I’m not a big consumer of pornography nor do I enjoy most fetishes but I generally share the attitude that you shouldn’t yuck someone else’s yum. Millennials are a tolerant sort. Yet I wonder if it’s time for us to revisit philosopher Karl Popper’s Paradox of Tolerance theory.

Karl Popper’s Paradox of Tolerance, introduced in his 1945 work The Open Society and Its Enemies, posits that unlimited tolerance can lead to the demise of tolerance itself. Popper argues that if a society tolerates intolerant ideologies without limits, those ideologies will eventually dominate and suppress tolerance. Therefore, to preserve a tolerant society, it must be intolerant of intolerance.

via PerplexityAI

I’ve have a lot of skepticism about how one executes on being intolerant of intolerance. It’s often illustrated with Nazis. Now there are many ideologies I find intolerable but as an American who believes in free speech I will fight for the right to be intolerant. As long as you aren’t trying to mess with my inviolable rights go ahead with your weird shit sexually, politically or otherwise.

Naturally this has yielded some people who go a lot further than you’d like. There is a Hacker News post that has come to be known as the “toaster fucker problem.” I’ll post it in whole so you can get the flavor of just how far people will go for their weird niche obsessions.

I blame the internet. Back in the days before it, we had to learn to live with those around us, now you can just go out and find someone as equally stupid as yourself.

I call it the toaster fucker problem. Man wakes up in 1980, tells his friends “I want to fuck a toaster” Friends quite rightly berate and laugh at him, guy deals with it, maybe gets some therapy and goes on a bit better adjusted.

Guy in 2021 tells his friends that he wants to fuck a toaster, gets laughed at, immediately jumps on facebook and finds “Toaster Fucker Support group” where he reads that he’s actually oppressed and he needs to cut out everyone around him and should only listen to his fellow toaster fuckers.

Apply this analogy to literally any insular bubble, it applies as equally to /r/thedonald as it does to the emaciated Che Guevara larpers that cry thinking about ringing their favourite pizza place.

Now you think surely internet fetishism has nothing useful to teach me. Surely this sort of thing wouldn’t bleed into serious spaces like politics or economics but after 2016 all bets are clearly off as to the seriousness of our political discourse.

Everyone is fully free to go to the absolute lunatic fringes of every issue because no matter how wild your beliefs you can find someone else online who shares it.

If you want to fuck a toaster not only will you find fellow fetishists but Rule 34 suggests there is probably pornography of it. Who could have guessed the consequences of 1987’s cartoon The Brave Little Toaster right?

Because totally regular people are no longer shamed for being into weird shit you can, and do, see totally regular people discussing weird shit. It’s often hard to judges what real and what’s fake. A Twitter shit poaster went viral for suggesting that Vice Presidential candidate J.D. Vance fucked a couch. The memes are amazing.

It was was fact checked as false by the AP and other news organizations. The comedians will never let it go as hey these days who knows the guy is a couch fucker. A popular Netflix cartoon called Bigmouth made horny treen fucking a cushion a plot arc so maybe the millennial senator from Ohio might be too.

Now as much as I’m all for presenting all sides of an issue it’s very possible that we can take people at their words. We don’t need to ramp everything up to toaster fucking. It’s perfectly fine to discuss things on the merits without going to the edge of the metaphorical map of social propriety. So I guess I’ll be looking for a copy of Popper on the book shelf this weekend.

Categories
Biohacking Chronic Disease

Day 1283 and nAChRs

Never one to take things laying down, I started a crazy “n of 1” experiment today. My family doctor prioritizes keeping up on literature. We’d chat about anti-inflammatory research in reputable journals.

But I am on week seven of Covid symptoms simply not clearing. I’ve been coughing when under stress or exertion, my seasonal allergies exacerbated the issue, my reconditioning of my cardiovascular system wasn’t going great and I was exhausted.

At a visit with my osteopath who helps with my chronic autoimmune issues in my spine (I’ve been diagnosed with ankylosing spondylitis) I mentioned my ribs felt tender and constricted from Covid coughing.

She asked me if I was familiar with the research coming out about Nicotinic acetylcholine receptors and Covid-19 treatments. She’s casual like that.

Now I am a child of the internet so I’m passingly familiar with Gwen’s work documenting scientific literature on nicotine but I had not ever thought I’d try it myself.

In a joking “don’t try this at home” way my osteopath said she’d seen folks use nicotine patches for a week to shorten their Covid symptoms to some success.

Now for some caveats. In any type of crazy self treatment it’s important to consider your risks and consult a professional. Don’t do anything without your doctor’s input. Every medicinal treatment has risk and side effects.

I am using going to use a 7mg slow release nicotine patch (of the type made for smoking cessation) for the next 3-5 days to see if it impacts my over-stayed their welcome Covid symptoms. I started my experiment at 9am Saturday July 6th.

I am treating this as a “kitchen table” science experiment in which I am clearly an N of 1 from which you can only take anecdotal evidence. But maybe one data point becomes many and with the network effects of social media maybe we push forward other experiments.

Here is what I know so far thanks to searches from perplexity AI but I encountered some of the papers through mutuals on Twitter, some on forums, others I’d discussed with physicians, some were just raw dogging Google Scholar.

The AI synopsis I’m sharing isn’t meant to be conclusive just to give interested parties a starting place to see why I believe this is an experiment I’m comfortable running on myself.

Nicotinic acetylcholine receptors (nAChRs) have been proposed as potential therapeutic targets for COVID-19. Research suggests that the SARS-CoV-2 spike protein may interact with nAChRs, potentially influencing the disease’s pathophysiology[1].

Nicotine and other nAChR agonists could modulate inflammation and the immune response, offering therapeutic benefits[2][3].

Sources
[1] Simulations support the interaction of the SARS-CoV-2 spike protein
[2] Disorders of the Cholinergic System in COVID-19 Era—A Review of
[3] SARS-CoV-2 spike ectodomain targets α7 nicotinic acetylcholine

Given that I’m working with inflammation as my primary issue which is not modulated even without Covid, I was obviously quite curious to learn about this cholinergic system and potential for up regulation. I’d seen discussions as early as 2020 about the curious fact that smokers had experienced some protection from Covid infections.

This all clicked in my head as being testable on my own without significant risk. Gwern had significantly reduced my concern about nicotine usage where previously as a child of the drug wars I’d put smoking nicotine in basically the same category of dangers as injecting heroin. It is not.

It seems it is possible we’ve got an explanation for why smokers didn’t catch covid at the rates you’d expect and they did better with the infections. We may even have things to learn from it to improve treatments.

Nicotine agonists could potentially be used to prevent inflammation in COVID-19 patients by modulating the immune response. Nicotine, a cholinergic agonist, has been shown to inhibit the release of pro-inflammatory cytokines, which could help mitigate the cytokine storm associated with severe COVID-19[1][2][3].

The cholinergic anti-inflammatory pathway, activated by nicotine, suppresses maladaptive inflammatory responses, suggesting that nicotine or similar agonists might offer therapeutic benefits in managing COVID-19-induced inflammation[3][4][5].

Sources via PerplexityAI.
[1] Nicotine and Covid
[2] Can nicotine alleviate the dysregulated inflammation in COVID-19? L
[3] Medicinal nicotine in COVID-19 acute respiratory distress syndrome
[4] Nicotine and the nicotinic cholinergic system in COVID‐19 – PMC
[5] Cytokine Release Syndrome (CRS) and Nicotine in COVID-19

Stopping a maladaptive inflammatory response is one of my top goals. If I can test it out with a cheap over the counter substance well I’m interested.

Andre Watson the CEO of Ligandal (not an investor just a fan) an AI discovery platform for precision targeting of therapies suggested a method of action for nicotine’s effect.

Nicotine and quercetin were some of the earliest predicted compounds to reduce the binding affinity of the spike protein to ACE2 — which in turn, we described the MOA of here: biorxiv.org/
TL;DR is that reducing the affinity may increase neutralizing immune response.

I do want to reinforce that I am aware nicotine is addictive. I’ve had to take drugs that form chemical dependencies in the past. I’ve used Prednisone in the less controlled phases of my spinal condition and tittering off that steroid is a nightmare. But it can be done. It is doable with a plan, careful monitoring, and supervision.

All evidence suggests this experiment isn’t long enough for me to develop a dependency let alone an addiction. I am thankfully free from any genetic predisposition to addiction in my family.

I plan to do a B3 Niacin flush at the end which is meant to help tittering. I will also be monitoring my heart rate as Nicotine has a tendency to raise your BPM so if I don’t like what I see I’ll lower dosage or stop usage.

With all that said, let’s see if it helps me out. I’ll post because it is in my nature.

Categories
Internet Culture Preparedness

Day 1261 and the Jackpot

Dedicated roamers of the internet are people who like to notice things. Cyperpunk aesthetics made it romantic to experience global abstractions even as the reality of the power of oligarch, state and corporation blended into murky dystopian reality.

I said recently on this photo that we’ve got to stop hyperstitioning William Gibson. We keep finding ourselves further into the future. Just look at these anonymous accounts (so you can enjoy being a participant in the propaganda) joking about a drone operator in Ukraine.

We have netrunners. They’re autistic Ukrainian drone operators and their ice baths are niccy rushes

It’s hard to remember that real people exist on the other side of the abstractions. And yet here we are about to be those real people facing history. And it does seem like the time for taking action is now.

Venkatash Rao wrote an essay “many shoes are dropping” that gave me the kind of frisson of living in future, but as Gibson famously says, a bit unevenly. Across all narrative and technical arcs and and inside geopolitical realities we are starting to see the change.

In this I can’t help but see Gibson’s Jackpot. The elements that Rao calls out are multiple significant elections (not the least of which is the final installment of Biden vs Trump), the capital and nation state power consensus he calls “after Westphalia” and the intertwined fates of artificial intelligence and crypto.

A lot can change in a world where every form of power is being tested. I’ve written about this Jackpot energy before.

The fictional “jackpot” described in the novels is an “androgenic, systemic, multiplex” cluster of environmental, medical and economic crises that begins to emerge in the present day and eventually reduces world population by 80 percent over the second half of the 21st century

The Jackpot Trilogy.

I myself think it a privilege to even be a bit player in this moment in time. That I can allocate resources in any way feels high leverage in a way I didn’t anticipate experiencing.

We are the adults in the room. It may not be mich but we have agency. I feel good about putting my focus on crypto, AI and nuclear energy. Like Rao I can tie together past thoughts across a wide corpus by writing here every day and make decisions based on what has emerged.

Categories
Medical Travel

Day 1250 and Viral Load

I very much picked up something awful and I suspect viral in Texas and am going to be coping with its fallout for a few days.

I’ve lost track exactly of its onset as my brain is scrambled by cold medication, decongestants and the process of being sick. You go very hard trying to show up for panels and dinners and then you find you can’t get out of bed at all.

I do find it modestly funny to crack jokes about being high on DayQuil and experiencing coughing fits so strong incontinence is a concern. But I guess it depends on your sense of humor. Yes that’s a diaper joke. Either way I’m useless to myself and others except as a source of amusement.

I haven’t had the sort of viral or bacterial load type infection that one would qualify as a cold or flu for sometime.

My immune system is so overclocked that your common cold barely stands a chance. I have endless autoimmune problems but actually having the flu is a bit unusual. I hope it passes soon. Till then I’ll be in bed hopefully not wetting it.

Categories
Culture Internet Culture

Day 1202 and Dazed and Confused

Bayes and I chat

only a few people seem to be thinking clearly about the powerful ai future. if your world model is built entirely off of samples from this app you are going to end up confused. if it’s built with zero samples from this app, you will also be confused

Bayeslord

I was raised by a good hippie so I couldn’t help but reach for a little LED Zeppelin joke about green text training our desires and fears. .

Been dazed and confused for so long it’s not true, wanting AI never bargained for you. Lots of people talk but few of them know the soul of the green text was created below”

Julie who should have asked chatGPT

I’ve got Dazed and Confused playing in my Spotify while I wonder how we remix our way to understanding if we’ve got a clear path through the dark forest.

There are many nodes and each signal you toss to the algorithmic winds sails to exact audience you are calling. Scream loud. Run the solo that shows you are a live one. Act on the systems. Reach out and take it.

Categories
Community Emotional Work

1197 and Experiencing Excellence

I was lucky enough to take Jonny Miller’s course “Nervous System Mastery” course year. If it wasn’t for me I wouldn’t have had an exceptional experience today with Joe Hudson.

There are many networked subcultures on the internet. I myself participate in many on Twitter dedicated to working on what I’d loosely term as “the human experience.” It’s a diverse flourishing ecosystem of seekers.

I myself have many posts tagged under “emotional work” which is the overarching theme of most of how I do this work. Under it you will find family therapy therapy, nervous system regulation work, somatic practices, and even a few hints the spiritual and metaphysical.

There are many footpaths to follow if you are part of the “Pathless Path” contingent looking to find your own way through the forest. There are many more walking through this forest in 2024. The many dislocations of the Great Weirding and The Pandemic break many narratives.

I see no one true path. The dharma bro jhana mediators are next door to the existential kink women. The cultural of revivalism has delivered neo-shakers and animists alike.

The many nodes of seekers has led to a network strengthening that has given me the strength to continue on this path.

I began this reflection with Jonny Miller for a reason. Last night he retweeted a public question and answer session and “rapid fire coaching” with Joe Hudson for the next morning.

Jonny had spoken so highly of the Joe’s coaching. I wanted to go. But I was also afraid. Joe said in his tweet “it gets intense” and I wasn’t sure if I was brave enough for it. And yet I showed up.

I thought I’d watch, listen and learn. And then suddenly I found myself in the presence of excellence participating myself with vulnerability. Such is the magic of a true master. My fear was no more. In just ten minutes. Such is the depth of his gift. It’s a gift to experience excellence in others.

Categories
Community Internet Culture

Day 1194 And Awesome

I wasn’t in the path of totality for today’s eclipse. Practical matters leave me less able to pick up for shared cultural experiences these days.

Nevertheless I followed along thanks to the livestreams from NASA conveniently running on multiple social media platforms. It’s definitely not the same thing as experiencing an eclipse (I was lucky enough to see the 2017 eclipse) but it was still incredibly moving.

A screenshot from the NASA livestream from Mazatlan Mexico

I had on public radio as well. I had run out to get food and ate my lunch as totality swept across North America. The NPR host went from county to county. You could hear cheering. One reporter who picked up for her station yelled “we are on the radio” as the entire station was clapping and laughing.

Coronal mass ejections maybe because of solar cycle timing?!
Categories
Media

Day 1184 and Discourse is Back but Sharded

The era of shared media narratives with simplistic framing and consensus seems gone. The information sphere is now like glass shards with many distinct realities according to Axios.

I think we have many more than twelve realities as class, politics, identity and material concerns overlap. The Internet has allowed all of us to develop esoteric and idiosyncratic knowledge. More types of reality are coming into contact with each other.

Because power laws drive the internet sometimes it seems like everyone is paying attention to the same thing all at once. We get crazily intensified reactions. People go absolutely bonkers over morality plays.

It was impressive to me to see New York Magazine create two intensely viral shared discourse moments in one week with their Dr. Huberman “scandal” and “the equally explosive “Age Gap Marry Rich” essay.

Being curious I looked up the editorial team and found it was journalists I recognized from my time in beauty and fashion. There was recipe for inducing cultural virality discovered by Teen Vogue in leaning into what is loosely call identity lifestyle. You experience culture like fashion or makeup through very specific symbols of interconnected identities. For some reason lifestyle choices makes people really crazy. It seems Lindsay Peoples the editor is a generational talent at evoking response.

The Cut’s new masthead changed from 2022

Categories
Internet Culture Media

Day 1183 and Not Personal

If you aren’t familiar with the term “parasocial” I’d encourage you to dive into the term and its impact on our culture.

Parasocial interaction (PSI) refers to a kind of psychological relationship experienced by an audience in their mediated encounters with performers in the mass media, particularly on television and on online platforms.

A parasocial interaction, an exposure that garners interest in a persona,[6] becomes a parasocial relationship after repeated exposure to the media persona causes the media user to develop illusions of intimacy, friendship, and identification.

Wikipedia Parasocial Interactions

Because so little in daily life feels personal or reciprocal as intermediation and automation split us off from past norms of one-to-one relationships, parasociality is on the rise.

You and I are likely to be in some kind of parasociality in this blog post. It’s not a new phenomena having been theorized as far back as 1956, but social media’s ubiquity has now put all of us into varying degrees of parasocial interactions with each other. We have opinions about personas from movie star celebrities to niche Twitter accounts.

We don’t seem to have these parasocial relationships just with humans. There was a an era of corporate brand marketing (that seems to be fading) where we interacted with brands like as friends. I followed all sorts of Twitter accounts for brands that acted like personalities in the golden era of “funny” Twitter.

Yet as more and more people are becoming brands it seems that the old school idea of a brand as a an amorphous corporation is disappearing.

Perhaps it’s because we encouraged the cultivation of personal brands as a professional marketing necessity. Millennials leveraged carefully manufactured profiles to climb the last remaining rungs of the old career ladder.

Naturally this strategy has some drawbacks. During the Great Awokening/Weirding we saw inexperienced humans cope with the ramifications of having a reputation that extended far beyond work, family and community. Now we loosely call it cancel culture though it took years for the term to become less contested.

I’d like to encourage more people to not take things so personally. It’s not bad for be in parasocial relationships. In life we have varying degrees of intimacy and boundaries in even our closest relationships. No one is exactly one person or even persona. Next time you get really upset at someone else’s behavior try to remember it’s not about you. If someone gets upset at you recall that this still applies.

Categories
Internet Culture

Day 1148 and ayyy lmao

Ayyy lmao

One of my Twitter mutuals Visa of Friendly Ambitious Nerd fame has a meme format he’s perfected with the Scylla and Charbrydis mythos that has become colloquially known as ayy lmao.

If one must sail between monsters representing inescapable and opposing existential threats (yes that’s a metaphor for life) then the only path through is to just sail on.

I see a lot of “fuck it, we ball” energy in the air now. It’s been emerging slowly but surely over the last two years or so. The inclination to say to hell with the odds represents a commitment to action. With Safetyism everywhere who wouldn’t simply want to say fuck it ayy lmao?