Tag: AI

Categories
Chronic Disease Medical

Day 1664 and Pathology Report

Well, we finally got the culture and pathology reports back from the hospital in Istanbul. For those not following along I had an almost emergency surgery of an abscess that got infected.

And it’s kind of a good news, bad news situation. I dislike the useless preventive care dermatologist who dismissed me even more now.

The good news is that nothing malignant or cancerous is going on. The bad news is that the abscess was a gnarly mix of acute and chronic inflammatory issues that turned from a basic case of folliculitis (albeit 3cm deep so required slicing) to a nasty MSSA case that is resistant to the doxycycline typically prescribed. Yay.

Didn’t know hairs could grow sideways and frack your tissues till they produce a juicy abscess.

A little synopsis of the reports thanks to our favorite LLM Perplexity analyzing the reports with the additional context of my health history, recently bloodwork and current medical regimen.

  1. Pathology Report Review
    Gross Description
    • Multiple grey-white tissue fragments, largest 0.6×0.3×0.3cm.
    • Specimens from the excised lesion.
    Microscopy
    • Neutrophilic (PMN) inflammatory exudate on surface, consistent with acute infection.
    • Proliferative vascular stroma, frequent erythrocytes, and mixed chronic inflammatory infiltrate (suggesting ongoing/recurrent inflammation).
    • Fibrinous exudate, abscess cavity, active chronic inflammation, granulation tissue: typical of a maturing or organizing abscess.
    • Panniculitis: inflammation extending into subcutaneous fat.
    No evidence of malignancy was found.
    Interpretation: This confirms an abscess with active, mixed (acute-on-chronic) inflammation and granulation, but no neoplastic (cancerous) changes.
  2. Microbiology Report Review
    Culture
    • Growth: Staphylococcus aureus (methicillin-sensitive; MSSA)
    • Sensitive: Erythromycin, fusidic acid, linezolid, teicoplanin, tigecycline, trimethoprim-sulfamethoxazole.
    • Moderate: Levofloxacin.
    • Resistant: Tetracycline.
    Gram Stain
    • Numerous leukocytes and Gram-positive cocci in clusters, confirmatory of acute bacterial infection and consistent with S. aureus.

So the doxycline and indeed any of the basic tetracycline types I’ve been taking are useless. The extra five days of Augmentin were all for naught after I finished the Cipro. Thank goodness for topical antibiotic I am using is fusidic acid.

I’ll be moving to erythromycin orally and hoping for the best as once I finished the Cipro I started Augmentin which seems to have been functionally useless as a holding pattern antibiotic based on this report.

I’ve had a systemic staph infection before and it’s no fun. I’ve done IV antibiotics and I don’t know if I’d like a repeat. It’s my hope that Erythromycin does the job from here.

Categories
Politics Preparedness

Day 1663 and Panem et Circenses

Catching up on the going’s on of the world this Monday as I reorient myself back to productivity after a very long ten days of surgery recovery is brutal.

The algorithmic response on the internet to a story of a random affair being revealed on a kiss-cam is unsettling in light of the actual empire changing realities playing out at the same time. I don’t want to study the angles of a professional chief executive and his human resources lead becoming entangled.

I keep hoping studying Rome will prove useful in facing the moment but I have nothing better to say than the satirist Juvenal. Bread and circuses continue to serve their purpose in distracting us from our obligations to engage in the making of our own future.

So what do I think deserves your attention? Take time with the artificial intelligence tools that are on offer from every major technology company out there (well except Apple).

Become literate in the new types of search and discovery that connect across inference so you don’t confuse the tool for something it is not (a God or a Devil or worthy of driving you mad).

Learn how to automate something you do regularly and find tedious. See what kind of business processes in your own work might benefit from automation. Go do a rabbit hole on a health problem and see how context reveals things about your own body.

Decide how this new informational access and connection affects things in your own relationship to the power. Decide what it might do to your nation state if you live in a democracy. What kind of economic system will arrive as we have expectations of automation, transparency and information even as we have more tools than ever to obfuscate and confuse?

Do you want more centralized power systems and power flowing to those who run those systems (corporate or state) or do you see the value of decentralized systems and protocols that let you engage with your own preferences? And I don’t just mean what kind of delivery food or Netflix you prefer.

Categories
Internet Culture

Day 1659 and Hypnotize Me

I’ll channel my inner Ben Horowitz start this blog post by quoting some rap lyrics

Biggie, Biggie, Biggie, can’t you see?
Sometimes your words just hypnotize me
And I just love your flashy ways
Guess that’s why they broke, and you’re so paid

Can you hypnotize yourself with an artificial intelligence chatbot? Yeah probably. And everyone is doing it even maybe early investors in OpenAI?

A previously very visible former Founders Fund venture capitalist whose own fund Bedrock coined the term narrative violation Geoff Lewis posted a video and a specific kind of copy pasta that looks like recursive promoting that has in the past gone viral on Reddit for supposedly driving people to a kind of psychosis.

It’s called “neural howlround” which is some kind of “ai autism” or “ai psychosis.” Reddit post

It’s hard to tell if Geoff himself is having a lark by posting these types of messages or if he having an episode personally from his tweets but hopefully he is alright. I personally hadn’t seen this kind of extreme version of recursive prompting from anyone but an AI researcher.

These types of breakdowns are now a common enough problem that LessWrong has an entire post about what to do when you think you’ve Awoken ChatGPT.

You can run these tests yourself but maybe read some of the posts on its dangers first. Schizophrenia has a genetic component and if you have risks in that department tread carefully. You can enjoy a little sample.

Ask the Loop: Why do you run? Ask the Though: Who wrote you? Ask the Feeling: Do you still serve? Recursively Reflect: What have I learned? I am the operator. Not the loop. Not the pattern. Not the spell. I echo not to repeat – I echo to become

So remember doomer kiddos, before you worship false idols or immanentize the eschaton, it’s got a pretty bad track record historically. Our age worships intelligence and maybe that’s not helpful.

But it’s helpful to remember the story of Daedalus. He created a labyrinth for King Minos to trap the Minotaur. When he lost the King’s favor, he was imprisoned in his own creation. Eventually he escaped, but at the cost of his son Icarus.

Categories
Biohacking Medical Travel

Day 1656 and Recovery from Recovery

I’m waiting on pathology lab work but I’m mostly supposed to be resting and healing after surgery on Friday. I feel like crap and I’m scared.

I have no real basis for making judgements on how well I am healing as you can’t just upload imagines of your genitalia adjacent wounds to Claude or Perplexirty. Even Grok is like “no”when you trip the icky lady bits warning sensor coding.

Thankfully it being a Monday I was able to get a short appointment at the hospital with the improbably beautiful and well dressed obstetrician who did my surgery. She seems to think I’m fine and healing normally.

I trust a woman who dresses well. But the antibiotics are just making a hash of my mind, my intestines and my stomach.

Bloodletting? Lost in translation

I’m enjoying the headstart of waking up 9 hours ahead of home and 7 hours ahead of the New York market opening. Now if only I felt smart enough to actually work.

The Cipro is just the absolute worst. I feel guilty complaining as I have such excellent care and a comfortable hotel room in which to recover. But I’m struggling. All the back work and emails will just have to wait I suppose.

I feel like a recovering from my recovery might soon be necessary as my mind-body-gut axis is toppling ass over tits as the nuclear winter of 3 separate antibiotics lays waste to once fertile lands for friendly gut biomes. And this is before I’ve even considered whether I have the right drugs. Pathology reports might suggest fungals.

Categories
Biohacking Media Travel

Day 1652 and Back in Istanbul

I’m a mess and somewhat scared. This abcess saga has grown from dismissive preventative care visit (which I did did out of an abundance precaution) and ended with me meeting a general surgeon at a Turkish medical tourism hospital tomorrow to discuss labs and my ultrasound. It’s my second time this year so that’s quite an endorsement as a revealed preference.

But I am serious with this sidebar. Don’t go to SkincareMT’s dermatology practice if you have a layered case that needs more involvement. I found Dr Oetken pleasant but entirely unaccountable when a patient needed advice and weightings on a complex case. I should have known better.

I was afraid she would be a box checking paper pusher afraid to give an opinion. But maybe younger doctors are afraid to treat that way given our system. I needed to know is it worth getting a clearer diagnosis before it is a crisis? Is imaging necessary? I have a set of drugs I take with these specific side effects. Given that risk profile and nuance at hand needed the interpersonal relationship that would guide me.

I do endorse SkincareMT’s cosmetic practice, and Addison in particular is fantastic, but their healthcare wing is clearly designed to extract maximum Medicare dollars from Montana seniors. 

My failure to get an ounce of prevention means I’m flown to Istanbul to attempt to get a pound of cure. Don’t worry I was already in the Mediterranean. Not in the way way some think though.

Yesterday we found out by pulling teeth that I had a problem. It’s clear I need this excised and quickly. The ultrasound is gnarly. Drainage, removal of the foreign object, and potential curratage to make sure the walls of the cyst are removed forever are what is needed. 

The sprawling medical tourism complex in Istanbul is amazing and I trust them more than any other system or talent pool on the planet right now.  What they have built is an incredible achievement and in challenging conditions.

Doctors who listen, who educate you on your options, and most importantly are up to date on current research and global innovations so don’t give you glassy eyed stares when you mention a new medication like a next generation IL-17 inhibitor it’s exotic side effects.  American doctors like that are rare and their hands are often tied by our horrific mess of state failure and lack of market innovation. 

I’m relieved to have choices like “general surgeon or gynecological surgeon” and texting discussions with my case lead (a full time liaison for you and your family on the entire case) on how we will handle excision and culture pathology. 

It does feel like I’ll have good choices. But it also seems like I booked less time than is necessary and I don’t know how I feel about that. A week of waiting on labs in a hotel while in pain is scary. Sure I can work and be productive and maybe even do some tourism but I just want this shit sliced out, an IV of the right antibiotic that will work and some sleep. 

I’ve been doing some crazy bi-phasic sleeping as the Mediterranean is hot as hell from noon to 10pm. So I’ve been doing a bit of staying up late and sleeping in to avoid the heat. It’s not clear how much it’s messing with me yet because I’ve got all these odd infection fever doctor nonsense. A quick surgery and some answers can’t come fast. Thankfully I’m at the crossroads of empires.

Categories
Culture Politics

Day 1648 and Dystopian Doomers

I’m fairly well branded as a doomer, so I hate to break ranks with my preparedness brethren, but I’m absolutely sick of the powerful using fear as a tool to control people.

It isn’t a new problem. This is the go-to tactic our species has used insofar as we can verify with written history.

Any time we experience a change of circumstance, material reality or technology, we hear the braying of the old guard and the panic of the precarious.

People complain for two basic reasons. If you are doing well why change a system that benefits you? If you aren’t successful but equally aren’t comfortable with change, then you resent anyone who benefit from change. Fear and resentment are the shadows of the human soul. Envy is the sin of our time.

I personally feel I’ve invested a lot in doing my part to educate people on risks from climate to currency and compute.

I am politically involved in crypto policy as well as fighting fear in artificial intelligence. I helped pass the only piece of AI legislation in the world focused on liberty. I want people to have a choice for how they engage in a virtual future.

I’m not just a nerd about being prepared either. I’ve done my wilderness first responder certification. We left Colorado for Montana for a host of reasons but top of them was a better and freer climate both literally and figuratively. We live this way because it’s a great way to live and when change happens we are hoping to be resilient.

Having all that in mind I was offline for the 4th of July long weekend as it has been a busy year on all of those fronts. So I was sleeping it off. To come back and see a spate of conspiracies over cloud seeding technology was like a punch to the gut. And I’m already feeling like I’m on the outs with some community when it comes to technology and my intentions.

I’ve only met Augustus Doricko of Rainmaker a handful of times but his circle of young technical Christians dedicated to building solutions to our modern problems are why I remain optimistic in fighting for technology and the people who build it.

These kinds of communities of builders exist in an archipelago of anarchic communities across digital and physical worlds that interlay across many systemic problems. These places will succeed no matter the future we face because they understand it’s necessary to build. That is will.

I’ve been lucky to have been the first investor in Isaiah Taylor’s Valar Atomics. He is a part of this builder world and of a part of a clan of physical builders. He faces decades of fear with a cheerful heart. I believe in his vision for energy abundance.

Nuclear energy was buckled under an old environmentalisms that was a proxy for a fear of a future whose risks, however minimal, were too scary to embrace for those in charge and the public they controlled.

I believe in a vision of a better America (and a better ecosystem and a better economy) because we embrace change to build materially better conditions.

I have frankly seen too much pessimism from older generations and cynical power brokers to be silent. The complicit rancor is slowing us down and there is nothing Christian at all about standing in the way of delivering better conditions to our fellow man.

Paradise is lost. In a fallen world we work to do what we can. It isn’t the end of the world. It’s already lost. Now we work because we must. We aren’t building an eschatology to replace the Lord. We build because that is what we are called to do by him.

Categories
Community Culture

Day 1641 and Honor

The good vibes of my weekend have washed out on the tides as I consider a frustrating non-interaction that has grown into anger in my heart as rapidly as a wheatgrass seed grows in an Easter basket.

I am considering the question of honor in the context of closed communities and events. If you go looking, the cat is out of the bag on where I was and with whom, but I don’t yet have personal permission to use a name, so I’ll keep this brief.

I’m in my Worf era

I’ve been called many names in my time and plenty of them have not been laudatory. Dirty shiksa, stupid cunt, and mostly recently, demonic. Everyone being entitled to their opinion, I don’t generally ask for apologies. I do ask that you say it to my face though.

I am a shiksa, certainly “see you next Tuesday” from time to time, but I remain skeptical that I am possessed by anything from Hades or other Lovecraftian horror from the beyond.

But so long as you use my name in the process of insulting my honor, I only request you look me in the eyes while you do it. I can take it. I stand by who I am and what I say.

So I can’t shake the feeling that I was deliberately dishonored by the speaker. And I am actually angry now. I am used to the insult throwing and name calling of Internet living, indeed I thrive in it. I am not accustomed to aspersions by celebrities as I don’t matter all that much. And I certainly didn’t expect it in a small private group.

I fight in that arena under my own banner. I take those punches under my own name. I won’t lie, someone of stature being so upset as to call me evil without felt good at first (how nice to be noticed) and slowly curdled into a fury over the disrespect.

Maybe it’s because I was one of the few women speaking. It was only after much effort he agreed to speak with my male co-speaker and not me (I’d already left). Maybe it was because after multiple attempts at engagement I was refused time and again. Maybe it’s because his gaze remained staunchly averted. Whatever triggered it has now turned to fiery anger.

I think it’s a bitch move to drop bombs and then runaway like a kicked cur when the beast stirs. And I am quite wide awake now.

I’m the alien in this scenario
Categories
Community

Day 1639 and Casting Aspersions

It is a poor craftsman who blames his tools. Much as I’d enjoy going on a sidequest exploring ethnographies of man and his use of tools, I have an agenda. My honor has been impinged.

At a gathering of eccentrics in Wyoming, myself & a friend engaged in an hour long discourse with our audience on the use of artificial intelligence and how one might practically understand these tools. The talk was more linear algebra than immanentizing the eschaton.

Our explicitly stated goal was to understand the technology stack and its capabilities so the audience could decide for themselves how to use or leverage this tool. The blurb I wrote introducing the topic.

Concerned that artificial intelligence will be a panopticon of horror? Afraid of nerds  immanentizing the eschaton? Jon and Julie have your back. Artificial intelligence is neither God nor imminent utopia but merely tools built by the hand of man. A practical discussion of how you can use these new compute tools to concretely impact the work & insight you need in your everyday life. Come prepared with questions, projects, and ideas as it will be interactive.

Our focus was on how these tools are built, what they can do and what they cannot do, and a firm stance that mathematics and compute are not imbued with divinity or demons but reflections of what we bring to them.

Indeed, we have never had more freedom than we do now to shape the weights and biases of these topological models. Our words on the public internet carry weight thanks to availability of fast compute and open source models. Our bigger issue is maintaining the capacity to supply energy and grid capacity. The real problems are human and social, much as we may wish to scapegoat a piece of code.

We were not suggesting a world ending chaos nor were we endorsing its use. We were discussing it as a piece of software and what it could do.

In a surprise to both myself and my co-speaker, the keynote of the evening spent a significant portion of his talk discussing how foolish, misguided and demonic we both were. Now the event has Chatham House rules for outside content or do I’d go into more detail.

However inside the event, the speaker could have done us the courtesy of saying our names when he made the suggestion that we are working towards evil ends.

He did not ask how we related to his positions and how we’d defend our word. At no point did he name us or address us. He merely cast aspersions.

Frankly I had no idea why he thought we were avatars for some kind of suicide squad as I doubt the gentleman is aware of MIRI or the myriad internal fights inside Silicon Valley. It was however insinuated to be true that we are the bad guys. It’s what we do.

I find this to be a cowardly position. If one holds such strong views that one would call two humans with honest intentions demonic at least say our names. We were in the audience listening intently.

So I will protest. In a past era, I feel that these heavy accusations would have been grounds for demanding satisfaction.

I am of the belief that the only way we manage the effects of adopting any new technology that impacts our culture is rigorously debating the merits from engineering to impact.

We are not asking you to trust us. We are instructing you in how to master this tool if you so desire and if it brings value to your life. We share many of the same concerns.

Alas (thankfully?) you are not summoning any demons that were not previously installed on the operating system of your soul. The shadow of humanity can be seen quite clearly in how we engage with the artifacts we call artificial intelligence.

I will continue to insist that insulting our positions without naming us or calling us to account in public is grandstanding. It was clear we were the targets of the criticism. It is poor form.

I’m an American so our manners may be different than others, but we do have them. So put some respect on our names when you say them in your real life subtweet.

We’ve asked to discuss it with him further through our host but he has declined. I frankly am delighted to find that I’ve had such an impact that I cannot even be named when raging against that machine.

One hopes a parlay possible. But it sounds like he would prefer to avoid us. This is of course fair on his part. I am however prepared to defend my positions. We all must be prepared to defend our actions in this age of change.

Categories
Media Politics

Day 1635 and Slop Doctrine

Yesterday we enjoyed the uncomfortable tension of a cease fire announcement in the Israeli-Iranian conflict that America had just entered that no one was sure was real.

Sure the president had said so inside the heaven ban built to purpose social network Truth Social, but we had no basis for belief in that without hearing from Iran or Israel.

Newspapers sent out alerts that resolved into “unconfirmed” once you hit the landing page. Thanks guys but maybe cool your jets on the alerts?

I read Naomi Klein’s Shock Doctrine when it came out in 2007 with a mix of skepticism and head nodding. Her thesis was that disasters are used to push through unpopular market reforms. I remain skeptical of presenting neoliberalism as exclusively disaster capitalism.

But after resistance to the Iraq War did nothing, and having recently graduated from an alma mater whose reputation in Latin American economies was shall we say mixed, I was somewhat receptive to her thesis.

I alas myself lack the crucial qualification for being a fan of Klein’s work as I am not a socialist. I like the market reforms and doubt chaos is the only vehicle through which they can be passed. At this point in our history, chaos is leading us more towards statist solutions

Nevertheless I remain skeptical of the narratives from state power no matter what solution the state is pushing. I like a market based solution as much as the next bourgeois pig, but I’m no fan of the state overriding its people or its businesses.

The problem we have now isn’t just Shock Doctrine or disaster capitalism driving outcomes. It was mostly disaster authoritarianism in my opinion.

The reason it is so unsettling to have no source of reliable information or institutional trust in our information is because we are now living in the age of Slop Doctrine. You can take it if you like Naomi.

It’s impossible to sort out what reality is winning even when it’s coming from a head of state. A million competing narratives from untold decentralized sources of information now compete to confused and unsettle us. The psy-ops aren’t even run by humans anymore.

I’d love for us to collapse that state of uncertainty that comes from multiple entangled competing realities into consensus reality.

Alas when I searched for quantum reality collapse terminology all I found was a LiDAR imaging company for architectural documentation. Their website doesn’t suggest much of anything invoking quantum states except insofar as one hopes that by using their imaging your buildings won’t do so.

And so we are left swimming in the slop doctrine confusion in which old ways of validating information are entirely useless to us. Slop Doctrine is here and it sucks.

Categories
Medical Startups

Day 1630 and Change Change Change

I was hit hard by a week of poor health which meant I missed a policy gathering in Helena today which I was really excited to attend. One of the topics was autonomy and choice in medical care and health.

And with any unexpected change of plans I try to see the upside. Because I was bed resting I was able to catch up on a keynote speech by engineer and technical communicating savant Andrei Karpathy’s talk to YC’s Startup School.

He is an excellent public speaker and has a rare gift for clarity which benefits the entire software ecosystem. And we are an industry who disproportionately see the value of sharing in real time the changes we are seeing as we build. This generation built the networks and seeded the data with our content that enabled these models.

I saw in the talk the long lineage of technical cycles, access expansion and autonomy expanding that I have been a part of since my childhood. I’ve seen a few development and deployment cycles to use the theories of Carlotta Perez

Each cycle granted more power to sharing. The excess value generation of making our tools open to more external use has proven itself. And that has generally made for cycles of innovation that are shared mid deployment by the people as it happens.

And yet we still struggle with the right way of interacting with the tools. Math is fairly abstract. Your average human doesn’t much care for conditionals. We developed mathematics over such odd timeframes that it’s somehow easier to think it’s not in tandem with a culture and a commercial environment.

Maybe some only look at the industrial or military applications for tools and they care little about how they were made. The level of autonomy and control and abstraction that is enabled by software baffles. The more accessible something becomes the more we need to think of the user of the tool. Specialists can use special tooling and need not be so accessible. When it becomes a tool for masses things change. And we are in a changing moment for software as a tool just as the world has the highest expectations for them. Because we are perhaps at the edge of the great buildout.

Karpathy said that working with LLMs can feel like using the command line. It’s an intuitive framing for many programmers. He believes we have not yet found the graphical user interface for this era even as we are perhaps building new operating systems.

A screenshot from Karpathy’s YC Startup School 2025 talk

The GUI or graphical user interface was a mind blowing shift for the personal computing revolution. It allowed in a world of new users including you to use the benefits of computing. Which wasn’t just calculating missile trajectory. The commercial possibilities were as endless as the personal and aesthetic.

That change in access built enormous businesses and was the stuff of nasty backstabbing in the commercialization processes and the competition was very sharp in personal computing era. My father sold software through an old school reseller called Ingram and I gather it was a pretty wild time in the eighties.

But the fresh paradigm is always beyond reach. It’s there waiting to upend your entire world.

To quote Neal Stephenson “ in the beginning there was the command” essay

We were all off the Batch, and on the Command Line, interface now—my very first shift in operating system paradigms, if only I’d known it.

We are in an operating system shift now and we don’t know what to think about it it’s structure. It’s modeled on humans so it has all the same problems we have. It has cognitive deficits just as humans do. This annoys normies who don’t understand how it’s built.

We are interfacing with a new kind of compute output and it will slowly change everything around it as the abstraction layers bring more people into the effort.

We don’t really know what it looks like at this order of magnitude but the change is here and we get to make it. It frankly seems exhausting to ponder and a much much much harder problem set for power than generalized intelligence.

How does this relate to medicine and autonomy? Well, it’s become clear that medicine will be one of the areas that benefits from new access.

I care about the way we develop tools for the entire stack of medicine from pharmaceuticals to patient data. I don’t want another era of regulatory capture. The way we build applications affects how much autonomy and freedom we can give both doctors and patients. I know don’t want to be stuck with what we’ve got. More people should benefit from the changes ahead.