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Biohacking Chronic Disease

Day 668 and Health Multitasking

I didn’t take my own advice recently. When folks ask me how to begin biohacking I tell them to take it slow. You should change only one variable at a time.

Biohacking requires that you don’t change up your variables too often or too quickly. You need to establish trend lines. The biggest mistake you can make is being “noisy” as you will never isolate the meaningful variables. And you won’t stick to it. So it’s a double fuck up. Clean reliable data matters. Don’t change too much too fast.

Day 91 and A Beginner’s Guide to Biohacking

My biohacking has been focused on improving my core inflammatory markers for several years. Secondary metrics like pain and energy got better as my erythrocyte sedimentation rate and C-reactive protein went down.

What I did to improve those metrics was complex, time intensive and expensive but it was pretty clear what outcome I was pursuing. My broad goals were simple. The tactics merely a function of one overarching strategy to lower inflammation.

Recently I’ve been a bit sloppy about my goals as my SED rate and CRP approach normal. I got excited that I might be stable enough to pursue some new goals. I am always looking to lower my doses of pain management medications. But the real shiny object for me has been fat loss.

I’ve struggled to stay lean as several medications that improve inflammatory markers have weight gain as a side effect. I struggle with shame about my weight. So much of popular culture portrays weight gain as a function of poor impulse control. It embarrasses me on some deep core level that others might think I’m lazy. If immediately trigger’s defensiveness for me.

I can rationally know I was pursuing a responsible health by taking prednisone during acute phases of my illness, but a part of me is still so embarrassed by the side effects. What must people think of me? Even if I explain that it’s a side effect of medication I fear that it’s still perceived as been slovenly.

So I decided to go back on metabolic drug called ozempic because I just hate carrying excess fat. I thought I could add it into my routine. But I am not doing as well as I’d like with the side effects of the injection. I’ve now vomited two Sundays in a row and been unable to eat. That is destabilizing enough that it is impacting my other goals like a slow dose down of non-steroidal anti-inflammatory drugs.

Maintaining low inflammation rates with lower pharmaceutical intervention is obviously a huge goal of mine and far more crucial than dropping a few pounds of fat. Especially because my metabolic markers are all in the clear.

I just so badly want to put behind some of the visible markers of my disease. It was hubris to pursue ozempic when I know I have other metrics that are more important than my shame about having steroid fat. So next time you see someone who is overweight I encourage some empathy. You never know the whole story of someone’s health.

Categories
Biohacking

Day 663 and Bad Sleep

I realize I’ve had several days of “well shit seems badposting. The outside world is a bit kooky but my world is basically fine. It’s snowy and I’m cozy and I’ve got friends visiting so you’d think I’d be in a terrific mood. But I’ve had two nights of absolutely horrible sleep.

I have been tossing and turning. I’m in more pain than I’d prefer. My heart rate is up. And my recovery has been for shit. At 6am this morning I just fully gave up on sleeping and trudged up to the kitchen for coffee. According to my Whoop I’d been awake since 1am. The same thing had happened the night before too.

I have reasonably good sleep hygiene. Dark quiet cold room. I take magnesium. I have a wind down routine. I’ve got a good mattress. And crucially if I am particularly fucked up I’ve got a prescription for a downer or two.

None of that appears to have mattered. Not even drugs were able to keep me asleep. And it’s bumming me the fuck out. At a certain point I’ve got to assume I’ll simply be so tired that I’ve got to sleep through the night right?

I told myself that was true yesterday when I feel asleep within a few minutes of my head hitting the pillow. But a few hours later I was awake and in pain. I’ve tried to be extra active today in the hopes that I won’t repeat it tonight.

Categories
Medical Politics

Day 656 and Genetic Material Storage

What feels like a lifetime ago, my husband and I pursued fertility treatments. I didn’t have any known issues but we wanted to freeze eggs and embryos while I was still young. At the time we didn’t feel stable or wealthy enough to predict when having children would be feasible. It seemed like the responsible choice to have a backup plan. Everyone we knew was doing it too.

I remember a gynecologist telling me off for considering freezing eggs as she managed medical school with a toddler so surely an easier career like startup CEO would have no trouble with resources for becoming a mother. I never saw her again after that incident. But knowing me the shame I felt from her judgement simply cemented my decision to free my eggs.

But I was equally poorly served by the fancy fertility clinic that glossed over risks and side effects. In hindsight I wish I’d been more concerned about ramifications. I also which I’d listened to my gut which was screaming that this felt more like a luxury shopping experience than a major life decision. The ease with which I was being sold a life where I could buy an insurance policy about a decision that I was ambivalent is almost shocking.

Now I’m faced with another choice. The genetic material needs to be moved to a safe state. In the wake of Roe v Wade being overturned, there is concern that fertilized eggs (embryos) might not be fully under our control as red states pursue stricter and stricter control policies. No one is quite sure how embryos will be treated. And frankly no one wants to find out.

Embryos that were stored in states like Texas and Florida are on the move. Clinics and storage facilities cannot guarantee their safety and usage as too much is still uncertain. Of the storage options we have, only two are in safe states unlikely to be impacted. Minnesota and Connecticut.

We picked Connecticut. Even if Republicans take it over we are banking they will be of the WASPy moderate types who see value in family planning for nice white married couples. Our privilege is at maximum there and that’s worth a premium.

I am so conflicted on even addressing the issue of what we are supposed to do with our generic material. Is this the moment we give up and admit it’s not a life path that we want? The chances of Alex and I have children together are getting slimmer. It’s not impossible but it’s also not looking likely.

My health is stable but I use several pharmaceuticals that shouldn’t be used during a pregnancy. I’d need to be on bed rest and dosed off everything to proceed with a pregnancy. I’ve been warned I could lose my progress on controlling my autoimmune disorder, the worst case scenario is I’d have to repeat the last four years of stabilizing treatment. I would be in a lot pain that couldn’t be treated for the duration.

Needless to say I’d not be able to work during the pregnancy and possibly for an extended time after. It feels perilously close to a choice between living my life and organizing my entire life and healthcare for a child I don’t even know if I want. It might be a permanent off ramp from work as the recovery would be significant. Everyone says you will regret not having children but I’ve only ever met people who regret having children.

At which point I have to admit to myself I don’t want children so badly that I am willing to be physically debilitated for another five years. I am so excited to be living a semi-normal life where I can pursue my personal and professional goals. The last few were hard. Perhaps we could pursue surrogacy but that suggests a level of wanting children that I just don’t think either Alex or I have. Because neither one of us strongly desires children this additional effort and cost simply to preserve our own genetic material isn’t under consideration. If later on in life we find our preferences changed we are both comfortable adopting or raising children not related to us genetically.

Perhaps the problem was that we never strongly wanted children in the first place. Maybe that shitty gynecologist was right. If we’d wanted kids we would have found a way. Instead we bought an insurance policy. And now that insurance policy is a scary liability with an uncertain political future.

With the way America is headed if we don’t move the embryos to a safe state now it’s entirely possible the government will decide we actually already have children. Unborn children. Who might have more right to life than I do. To be honest that’s an ethical question I don’t have an answer to. All I know is that I am absolutely not willing to let the government decide if it is my life or the embryos. That’s between Alex, myself and God.

Categories
Emotional Work Startups

Day 655 and Accountability

Being accountable to myself is much harder than being accountable to someone else. I suspect this is true for most people. We all wish for ideal childhoods with parents who provided for all our emotional needs. And so we look to bosses, spouses and authority figures as substitute parents.

Most of our adult lives are spent trying to find some ideal mommy or daddy to soften the trauma and lack of our childhoods. We remember these issues far too vividly as adults through the perceptions of our inner child. It is a huge challenge to recognize that feelings are not facts but these feelings nevertheless run our lives.

The unfortunate truth is that the only ideal parent that can ever exist for our inner child is ourselves. We must comfort, protect and nurture that part of ourselves that still feels lacking because no one else can give it to us. No one is coming to save us. We are the parent to our inner child.

Which brings me back to my challenge with being accountable to myself. I struggle to care for myself the way I need as I too often perceive myself as not being good enough. If I just worked harder or spent more time preparing or if I just did one more pass on my pitch deck. You get the idea. I’ll push myself right over the edge of success into inaction and self torture.

One way I’ve been able to overcome this need to push myself into a fantasy of accountability is simply by building in public. If I’ve said what I plan to do then I’m no longer just cultivating it inside myself but I’ve let the idea come forth into reality. Once it is outside of my own tortured bubble of personal accountability it can gain momentum.

I am raising money for a venture fund and now that I’ve put that in public it’s not just about me. It’s about the thesis, the LPs, the founders, and the market. And it’s much easier to be accountable to a shared reality with other people than some fantasy version of perfection inside my head. If you’d like to be a part of it and are an accredited investor here is a link to my calendar. If you’d like to read more about the fund I’d be thrilled.

Categories
Emotional Work

Day 653 and Flat Lay

I am “enjoying” the monthly gift of a horrific migraine pattern courtesy of my Aunt Flo. It appears to be one of those all day twenty four hour beasts. I am laid out flat from it.

My suspicion is I made the symptoms modestly worse by barreling through the past two weeks in my enthusiasm for my life. Life is good and that presents some challenges for me in over doing things.

The world may be unraveling but the personal realm of Julie Fredrickson has rarely been better than it is now. As it turns out, moving to Montana was an inspired long term investment right from the get-go. So naturally I want to share this good fortune with my most beloved. We’ve had an influx of friends and family.

One of the spiritual guardians of the the homestead is Elle Morrill. She was with us when we found the farm and made an offer on it. As we built out our guest rooms, Elle’s Room, has been name that stuck. As you can imagine, I was beyond excited to have her come visit for my birthday.

It is a beautiful thing to feel loved and cared for on one’s birthday. This whole week has been a rush of joy and support, running the gambit from being fed and nourished by Elle to being welcomed and aided by wider the startup community with my fundraise for chaotic.capital.

I can feel myself expanding and reaching for new competence and new horizons through the efforts of my friends. Elle made a Coq au Vin. Is there anything that says a love language quite like feeding someone? My love language might be writing but I think this gesture is easy to translate.

Coq au Vin or Chicken in Win with rice pilaf.

But nothing sweet can be enjoyed fully without a hint of bitterness for contrast. Light is only illuminating against the presence of the dark. A painting without shadows is flat. And so the flat lay photographs of sumptuous gourmet meals made with love and care by someone I love perhaps has to be contrasted by being laid out flat with a migraine.

So as I lay flat in bed yearning for the energy to be with Elle, with my work, and with my life, I must remind myself that the work of art that is my life needs the shadows too.

Categories
Biohacking

Day 652 and Startled Awake

There are few things more disorienting than waking up without realizing where, or even when, you’ve fallen asleep.

The first few moments of regaining consciousness are the stuff of genuine terror. As your senses do their best to bring their data to your brain, there are a few agonizingly slow beats where you genuinely have no idea what the fuck is going on.

I imagine this phenomenon is where our vocabulary of phrases like “startled awake” get their origin. Perhaps you weren’t awoken by anything surprising, or particularly startling, but the small gap in processing between sense and mind is such a chasm in that singular moment that it all feels startling.

I had lay down to wait for a Midol to kick in to ease my first day of menstruation cramps at around 1:30pm. I remember asking my husband if he could find a heating blanket. I don’t remember much past that except a few hazy details of wrapping my entire lower torso with a heating blanket.

I had not turned off any lights. Nor had I thought to put on a sleeping mask. I thought I was simply waiting for the sweet relief of caffeine, Tylenol and diuretics. I had even told my girlfriend Ellie who had been expecting me to come up upstairs to hang out that I just needed a quick lie down. Turns out the lie part was true. It was not quick however. Which is some fun wordplay.

When I regained consciousness I had no sense of how much time had passed. As I fumbled about for my cell phone I swear I felt my neurons firing off rapidly in an attempt to gain data points for my poor addled mind to do some damned interpreting.

I was wrapped in something hot with a cord. Did that mean I wasn’t in my own bed? I didn’t generally sleep with anything electronic. I briefly panicked as I felt trapped in what was previously providing my body with comfort. I’d forgotten about the electric heating blanket, leaving the cord with no other function but to panic my hind brain with a fear of being strangled.

As all my lights were on, the various lamps were washing out any indication of the hour. I could hear noises above me so perhaps someone was awake. Did that mean it was the afternoon? What was with all the stomping above. It felt like it must be day.

I simply wasn’t getting enough orientation information from my initial position and I couldn’t seem to find my phone. I doubt more than a second or two has passed as I went through my startled awake process.

As I attempted to make sense of all these inputs I finally realized that I had passed out on top of my phone and I’d let it slip under my pillow. It was a bit past 3pm. I texted Ellie to let her know I’d accidentally passed out. The brief pumping of adrenaline and cortisol was easing back. I was at home in bed quite safe and a bit overly warm. But I certainly felt a new appreciation for the limits and frailty of my human mind.

Categories
Aesthetics Community

Day 650 and Reaching

Yesterday was quite a day. I decided to commit to doing a fundraise for chaotic my fund in public as it was my 39th Birthday

I would like to raise $5m for chaotic.capital’s rolling fund before I turn 40 next year. #5Before40 has a nice ring as a hashtag right?

If you would like to be a part of the fund grab a spot on my calendar and let’s discuss!

But lest you think I only thought about venture funds on my birthday I promise I did some celebrating with my family and friends. One of my favorite girlfriends came up to visit. She went straight from the airport to the food cooperative and stocked our half empty fridge with a full harvest of food.

A well stocked fridge

She then proceeded to cook a gorgeous dinner with grilled chicken and roasted cauliflower along with kale chips and a big mixed green salad with a shallot and fresh fig dressing.

Gorgeous, health and nourishing.

And lest you think the most important part of a birthday was forgot here is a picture of the most impossibly beautiful chocolate cake I’ve ever seen.

A chocolate birthday cake

I had a wonderful day filled with love and support. It’s only taken a couple decades but I am finally feeling like I’ve built a life where I feel secure, loved and cared for by those I’ve chosen to be in my life.

Categories
Emotional Work

Day 648 and Open

I share a lot of myself online. For an introvert with more than a hint of Autism you’d think I’d find it mortifying to be as open as I am online. My therapist would probably say it’s because I like the distance provided by sharing online and it’s hard to disagree. But I like being open to the world. I want to be a little beacon in the storm so that you might find me if you are looking.

But while I am so open to the public online, I am protective of my personal space for a number of reasons. I guard my health and my body as I manage a chronic disease. I prefer to operate from a place of non-reactivity as I like my central nervous system to maintain eustress. And I am not generally energized by spending time with others. I am energized by alone time.

But like any other human I do want to be seen. And I want others to feel like I am seeing them. I prize empathy and openness. Showing my vulnerability and weaknesses with the world is part of how I try to be seen and also let others know I see them.

My efforts to be healthy and my struggles with pain and fat are human problems. Maybe other aspects of my life are less relatable, but being worried about my weight and struggling with physical discomfort is the stuff of being an average woman.

I am perhaps overly sensitive to what I perceive as failures and short comings. I project confidence but it isn’t always natural. But I also recognize that, even if flaws terrify the part of me that is still emotionally a child, these supposed failings are the human condition. Everyone has elements of their bodies, their emotions and their intellect that they occasionally feel shame about. We are all working to let go of that shame.

I want the people I work with, especially the founders who are pouring their lives into their companies, to know that they are psychologically safe with me. Doing new things is hard. Creation is hard. Building is hard. Startups are hard. Shouldn’t your investors and advisors be a safe harbor to share those challenges with?

If you are feeling scared or ashamed or angry about yourself, I want you to know you are not alone. It’s ok to be open about your power and your accomplishments and your unique genius. And it’s also ok to be open about all the things you struggle with as well. You contain multitudes.

So if you see me putting out huge asks online or sharing incredibly embarrassing details, I want you to know it is because I see you and I trust you to see me too.

And if we are meant to be in each others lives then it will because we are capable of seeing the multitudes in each other. And if that is not for you that’s ok too. We all deserve to be loved as we are. I trust you. And I hope you might trust me too.

Categories
Emotional Work

Day 647 and Socializing

I thought I was being quite careful this weekend about not over socializing. Last weekend I was hitting up pancake breakfasts and running errands and I thought I was going to pass out come Monday. So I was much more conscious of needing to rest and privacy this weekend.

But no matter how much I dial it back it seems like any amount of interaction is just too much. I backed it down to two hours on Thursday, Friday and Sunday with a recovery day on Saturday. But here I am on Sunday afternoon fighting off a migraine from overstimulation.

Folks bitch and moan about Zoom and how it takes away from the human element of interaction but fuck me if that isn’t the entire appeal of it to me. I myself prefer asynchronous communication to buffer myself even further from the onslaught of audio, visual and emotional inputs. But I’ll take a day full of Zooms as it’s still so much less input.

Perhaps the downside of having the hair trigger central nervous system of an autist is I am simply absorbing more from the inputs than the average person. Every noise, every visual cue, every smell is hitting me. Others may need all those cues but I absolutely do not.

I wish there were a way to articulate this to friends and family that didn’t make people feel rejected. But socializing in person is simply so taxing for me that I need much less of it. And it’s not because I don’t like you. It is just because I’m absorbing way more of you than you think!

Categories
Startups

Day 645 and Progress

I was recounting a few pieces of work that have been ongoing to some family last night. Both items were the result of choices and trends I’d been following and cultivating for well over two years. One of the items was even set to debut next week. I had some demonstrable proof points that I was right and right long before anyone else took any notice.

I was extremely pleased to recount the long arc of work that had gone into these trend lines and how they were manifesting in successful investments and media attention now.

Usually when someone asks me what I do I have a tendency to stumble around a few more or less goofy bits. I am retired from working in propaganda. I am a house wife that manages the family budget (this works only with stay at home mom or high net work wealth managers). If I’m feeling chatty I explain the Thursday Styles Problem. If I’m not feeling chatty I’ll just say I’m an investor. Occasionally I will make an attempt to explain the founder to angel investor to venture capitalist career arc.

It’s not actually that easy explaining work that involves years of waiting. If you work for an established name brand venture capital firm it’s probably easier than being an angel investor with a small syndicate or seed fund. But even if you are Sequoia it still takes a decade on average to prove out your bets.

I’m thrilled to have concrete examples to point with any of my investment thesis points. I’m lucky that I have exposure to media so I occasionally get the chance to share what I work on online and in print. Not everyone has the skills to be as visible as I am. But it sure felt great to make some progress. And yes I promise I’ll share publicly when I can.