Testosterone – Julie Fredrickson

Day 1748 and Putting Testosterone Pellets In My Butt Cheek

Intrepid biohacker that I am, when I learned that my testosterone levels were concerningly low, I began on a program to raise them.

I started with nutrition and supplementation but I already had a diet and supplement routine that was evidence based for raising testosterone levels in women.

I added in DHEA (Dehydroepiandrosterone) at 25mg. Six months of that brought me up to just about half of the lowest baseline acceptable. I was NOT getting adequate results.

My physician prescribed me a cream from a compound pharmacy which unfortunately didn’t agree with my skin. So we were going to get creative.

I had read a blog post from Cate Hall (whose husband Sasha Chapin had helped me on another entirely different vector of my life) on how testosterone pellets changed her life.

She had had teeny tiny testosterone pellets placed into her subcutaneous fat and had remarkable results in terms of energy and focus. This and that happened, and the summer was a mess, but today was the day I finally followed in her footsteps.

We’re started me with 10mg of estradiol (range 6-25mg with 8-10mg being most common), and 75mg of testosterone (range 50-150mg with the most common being 75-100).

We’ll aim for labs at 4-6 weeks after insertion which would represent peak levels. We will repeat dosing at 3-6 month intervals. We will check levels at 4 months or so, or earlier if I feel the effects waning.

Do be warned that within a paragraph or so, there will be images of needles, scalpels, and some blood. So feel free to not scroll down further.

Part of the difficulty with dosing this stuff is that the pellet doses are wonky and frequently out of stock – estradiol comes in 6mg and 10mg increments so 8mg is impossible.

Naturally, we’ve made surprisingly little progress when it comes to women’s health, particularly as it relates to hormones.

But as I am happy to be a guinea pig and my luteal phase is a mess of migraines and misery I figured I had little to lose and much to gain. I was the first patient my doctor has done the procedure on so if anyone in Bozeman is interested, you can confidently give it a go with him as I’ve survived it.

These cool tubes don’t actually go inside too far but sort of shoot the pellet into the incisions

I was given a local numbing agent with epinephrine. I needed a surprising amount of it but I was a bit nervous. Once I was just able to feel pressure and no pain it was time to make a small incision with a scalpel and in popped the tiny bit of hormone on the left butt cheek.

No big deal at all.

But if you don’t want to see it going in don’t scroll.

Just giving you space to turn back.

A tiny incision in my goose bumped bum with the little pellets easily tucked in

I am all bandaged up and still riding the cortisone of it all but I feel alright. I’ll be adding in progesterone orally to temper the estrogen as that’s another matter. I’m excited to report back on it as if I have even a fraction of Cate’s experience with it I’ll be quite happy. Also it’s about $70 a month so not cheap but not at all expensive for something that could potentially mitigate some long term issues I’ve struggled with for years.

We spent a long time at the doctor’s yesterday as Alex and I gutted it out with our excellent physician (with AI assists) through a myriad of different tests. We were attempting to figure out why he keeps getting respiratory infections and why I’m such a tasty treat to skin bacteria.

In truth, my basic inflammatory biometrics have improved so much on the new IL-17a inhibitor Bimzelx that it’s probably worth the hassle of occasionally having to slice open a random effected gland or abscess once a quarter. It’s just a shocking amount of work to do whack mole with pathology reports.

What I don’t seem to be able to improve is my low testosterone and the flavors of migraine headache that come with the roller coaster of my luteal phase. Which is presumably a clue and we are following it.

Astonishingly my lady hormones are in tip top shape. Though the “you should have no trouble getting pregnant if we can get off the medicines that stabilize you” remarks remains a heads trip. Yes I asked.

It is not a head trip that makes one’s husband enthusiastic about the prospect. Which is fair, as we have no family support, no backup plans for me regressing physically, and the family that does support us can’t get to America. So one can see why a CEO husband with sick investor wife who would have to give up work, plus potentially messed up baby, isn’t super appealing. Anyways! TFR is a fun topic.

I started with basic supplements in the precursor category like DHEA and STRO about a year ago when my testosterone came in at a 2 nanograms per deciliter (ng/dL) when it should be somewhere between 9 to 55 nanograms per deciliter (ng/dL). For context, adult men typically have levels in the 240–950 ng/dL.

The one sticky widget is that my testosterone remains stubbornly low. You wouldn’t think such a raging “see you next Tuesday” such as myself would be overburdened with the feminine hormones and lacking in ball buster hormones but I am.

I managed to eke it up to 5 with supplements and nutrition but it really didn’t match my otherwise excellent hormonal profile. Having ruined my chances at a healthy immune system when we tried the first half of IVF, I’ve spent some time working on and with my natural cycles.

I loathe being in my luteal phase but when I’m in my follicular phase I get 90% of my work done. We had presumed it was the rapid decline in estrogen and progesterone but maybe my floor rate testosterone was more of the issue.

For the past 8 weeks I’ve been using a testosterone cream that clicks up your dose and you rub it between your thighs. I know it’s gross. So I was curious to see where I might land. And praise the Lord I am now at 15 ng/dL. From 2 to 5 to 15 is some excellent progress but still below where we’d like me to hit. So we are going to run another test and try out the tiny pellets they slice into your skin. Since I’m already used to scalpels and antibiotics I figure why not?