Tag: Venture Capital

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Biohacking Chronic Disease

Day 1471 and Lemons into Lemonade

I was so disappointed yesterday as I read over my most recent set of bloodwork and found my autoimmune biomarkers headed in the wrong direction.

I’ve been well controlled though my disease is not “inactive” or in remission. I manage it as it’s worth it to me to have a quality of life that includes working in technology as I want to be a part of making the tools that enable material progress in health.

Seeing things go in the wrong direction when my life is going in the right direction had a clarifying effect on me.

Not that I’ve been unaware that I must work at my health but rather it’s hard to always be working at health as it’s a matter of survival. But when you see a change in the data you act. I got serious and immediately went into action.

I’m so lucky to have to have access to an incredible community of biohackers. That I can ask someone who is studiously pursuing health in public is the best of the internet. I get the benefit of Bryan Johnson’s open sourcing his work. I’m doing an experiment with HBOT or hyperbaric chamber oxygen therapy and I learned from him I need it to be 2 atmospheres to be effective. This helps me plan and find hard chambers.

I can use Perplexity and Claude and even make my own personal assistant trained on my condition and my data is the remarkable thing.

I’ve found a new IL-17 inhibitor that looks to have twice the efficacy of my current one at the same dose. It was only approved in Europe but finally came on the American market. I was able to discuss it with my doctor immediately after going down a short question sequence on perplexity. You have so much power to improve your life now.

Shopping

I’d like to improve my V02 max and cardiovascular health in a way that works around my psoriatic arthritis and ankylosis. I have significant fatigue from the pain and obviously high impact isn’t in the cards for me. But I can try something like a DeskCycke. It’s even possible for me to do HIIT training with one. So I bought one. My goal is to improve my V02 by 10% in 8-12 months which shouldn’t be hard as mine is absolutely awful

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Chronic Disease Medical

Day 1468 and Going HBOT

I was extremely frustrated with an autoimmune reaction that got out of hand over New Year’s. I don’t care for taking corticosteroids as their side effects are quite severe even if they can be the only option when an immune response refuses to calm down.

To repair the damage, I went to a holistic clinic that offers a range of services like infrared saunas, IV therapies, cryotherapy and hyperbaric chambers.

I’d heard good things about using HBOT therapy for autoimmune responses, particularly ones that are rheumatoid in nature. I’ve done two sessions so far and I have seen a remarkably swift improvement in inflammation and pain.

I’ve got 8 more ahead of me along with some glutathione and vitamin IV drips so I’m hoping to be ship shape soon.

News and Sundries

The Chinese venture ecosystem has funds engaging in some suboptimal behaviors. They are clawing back personal assets, banning them from services and putting founders on no fly lists. Which is needless to say not the best way to encourage innovation.

Mark Zuckerberg is taking a new tack with speech at Meta. The company employing content moderators for what is true is out and enabling Twitter style community notes are in.

Many moons ago Antonio Garcia Martinez warned that Facebook shouldn’t be involved in policing and censoring speech as it would lead down a dark path.

Much To Consider

Is most memetic self help that propagates well online now predatory in nature? A tweet thread to consider for those looking to have emotions or control them.

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Internet Culture

Day 1464 and Which Information Island?

It would be helpful for most media readers to understand the history of the news business and its relationship to war and finance.

For all the standards and ethics and best practices we expect from professional newsrooms (and they do have conduct standards), the history of media isn’t a clean narrative America went to war thanks to Yellow Journalism in the Spanish American War. If you think the Pulitzer is a badge of merit wait till you learn its history and financing.

You have probably lived through multiple media scandals. Millennials remember the neoconservative “weapons of mass destruction” story thanks to notably terrible editorial decision at the New York Times.

When someone says you are in a media bubble or on an information island, recall that these systems made up of people with varied interests, ambitions and aims.

News

American Surgeon General Calls for Cancer Warning on Alcohol

TechCrunch grudgingly says the AI Bloomers beat the delusional AI Doomers

Essays

An Nvidia researcher Jim Fan tweeted about blog post from the late Felix Hill on 200B weights of responsibility inside the work of building AI. The stress of knowing the billions of weights and bias that make up artificial intelligence that will bend our lives for both good and ill is no small thing. The thread has many beautiful comments.

Vinay the founder of Loom is in the thick of figuring life out after success and it’s brave of him to share.

Applications and Services

AskNews has an interesting set of display options for news types and bias and sentiment I’m considering purchasing and testing.

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Politics Preparedness

Day 1437 and Back at the Ranch

I marvel every time I fly. My life rests on miracles and small issues like repair delays and malfunctioning climate systems can make the miracle feel too much like magic and not enough like good process.

I’m happy to be home in Montana after a couple weeks on the road. Financial markets are happy with certainty. So business is looking good and optimism is emerging in all sorts of corners.

And yet we are in the worst Cyperpunk moment of my life. I think about other uniquely connected moments and it’s got nothing on this.

The chaos has never been so visceral and implacable and it’s coming so fast. We’ve got extrajudicial killings of healthcare executives by gray man gearheads. South Korea declared martial law briefly. Syrian rebels are toppling Assad while America and Iran are otherwise engaged. And Trump isn’t even back in office.

I expect turbulence to continue. Both when I’m flying and in the wider environment. I feel as prepared as it’s possible to be with edge positions across the board and some distance from the center of the empire. I’m glad I’m back home.

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Internet Culture Startups

Day 1434 and Density

There is always a debate in startup life as to how the density of a given ecosystem impacts outcomes. A tight network of well connected communities and individuals helps founders, investors and talent connect.

Before the pandemic it was considered fairly normal to be within a major hub as the common knowledge was that “density” matters. You wanted to be in the action of a scene.

There are great startup cities. New York has an incredible scene. My hometown of Boulder has a great technical core. But as much as cities and companies compete over status the one with longevity is Silicon Valley. Heck it was a debate when that even encompassed San Francisco until Twitter moved in.

Then everyone spread to the four winds during the pandemic. I like to think of this as the era in which Silicon Valley got back to its digital roots. Being extremely online became a behavior that worked well for anyone if you communicated well with words. Being on the right coast was about being in the right online communities. The network state is online.

I’d say that was as pure a return to source culture as there ever was. Different people value signal across different networks and the open web of words has been home to software and hardware developers for generations.

The world that builds companies lives virtually as much as it does in the real world. We like to meet up but we also know it’s the tools that connects us that make the difference.

Every subculture that has emerged with a breakout hit did it through the digital commons we built together. I’ll always appreciate coming to the source culture to replenish but I know the density of the network is at its swiftest when our extremely online communities communicate.

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Culture Internet Culture

Day 1431 and Faking It

I’ve heard this multiple times across enough demographics in the wider “startup” ecosystem that I’m afraid I’ll have to accept it is happening. People are faking being weird. In some cases they are faking being autistic.

I find this to be an almost laughably unlikely thing to want to imitate. And yet I’ve heard it three times in the last week. The new poser is faking being a neurodivergent weirdo.

We regularly joke that at chaotic.capital a part of our deal sourcing relies on “Julie being professionally weird on the internet.” My pinned tweet from three years ago is a ramble on this ethos as it’s been true for decades. Unique fixations often undergird problem solving.

Being weird, or more specifically autistic, has now taken on a specific connotation of an intelligent but socially strange or oblivious character who sees the world differently. This means you are special somehow and can be forgiven for being a dick (that’s a lie be nice).

It was probably a source of pain for many millennial kids who were awkward the more oblivious you are the less it bothers you. Marching to the beat of your own drum. We’ve got a whole set of social tropes around smart nerds in popular media and most of them were negatively coded.

Despite this history, revenge of the nerds occurred. The power and dominance of technology (and its cousin nerd) culture means the spergy truth telling autist has cachet. We live in a post Sheldon Cooper world. Once something involves capital it collects social capital as well.

I have clearly underestimated how much this affects Zoomer behavior and incentives. Millennials experienced this archetype negatively but in a softer “everyone is special” culture your quirks can lead you to money and prestige. So there is now an incentive to act like a weird asshole to fake being weird and a little socially anxious.

If autism can have stolen valor then we might be in that era. It seems to greatly annoy the actually autistic (a tag on social media used by many poorly socialized entirely normal people) to have the symptoms of autism faked.

Authenticity is actually quite hard to fake and anyone with a decent social radar can usually spot it. Whether all autists have that capacity to read social cues is up for debate. It’s probably why anyone tries to fake being a genuine weirdo.

I’m inclined to say skills issue as the internet has made class, manners, and social cues much more accessible to everyone. And good news being every social class values being chill, real, and passionate. So there is no need to fake anything. Just vibe. Be cool.

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Startups Travel

Day 1424 and California Dreaming

We’ve just had a beautiful snowfall in Bozeman. If you are back up on the mountains at the edge of the valley you are enjoying a mystical winter wonderland.

Alas I am not long for cosplaying Frozen (blessed) as I am headed west. No, I am heading not to Seattle the most important city of the 90s. I am headed to Joan Dideon land. I’ll be in California.

I’ll be in Los Angeles for the week or so if you happen to be on the west side. I’ll then be headed up to San Francisco.

It will be a little whirlwind of family, friends and hopefully some useful business. I’ll be visiting start ups. Going to YC Demo day which I have not done in person. Meeting up with anyone who might want to be a node in our network.

I am game to meet up with folks working on weird shit and are looking to build it. I am also looking for LPs in our next fund so we can keep funding the weirdos who build things.

The virtuous cycle of techno capital starts long before an opportunity is clear. If you have something chaotic in your heart send me a DM

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Internet Culture Startups

Day 1421 and Culture Clashes

I sit in between half a dozen different community nodes thanks to my interests in open source software, decentralization, crypto, and autonomous systems technology.

This set of interest covers a lot of ground from ecosystem level collaboration in financial organizations like DAOs and to player versus AI agents coordination to peripheral control of drones and machinery.

Many different demographics are attracted to these frontiers for different reasons. Hackers have a very different mentality than mercenary technologists looking for maximum margin.

Open source has traditionally struggled more from a lack of financialization than from an obsession with it. Which seems less true in the crypto era than in previous more academic and defense oriented eras.

There are classic open source business models and anyone with age and experience in startups has some opinions which I leave as an exercise to the reader. They occasionally fail and an open core loses more than they’d like to professional services. I am writing on WordPress.

One strange aspect of what drives these frontier spaces to interact is that depending on how much leverage you find in building a network you may have different incentives than other builders and users. Expanding out to scaled use may drive a lot more value than the resources required. How the surplus gets divided is always contentious.

For some, the most crucial cultural goals is expanding access to automation and ripping away as many of the services and middle men as is feasible.

Decentralized systems make it harder for middle men to maintain monopolies. Thats its own goal for true believers. For others the goal massive financialization that drives network connectivity is the benefit. Self interest driving common goals is perfectly acceptable.

As I watch the current season of hyper self interested memecoin cryptomania engage with the academic utopian open source artificial intelligence community, I am reminded of so many of the classic issues we have in financing and sharing in the spoils of common infrastructure. Who benefits is a question we should all be asking more regularly

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Preparedness Startups

Day 1419 and Know A Guy

Running a startup, for all its supposed glamour, is mostly an exercise in learning how little you know.

Sure there are playbooks for some of what you will do. As the technology industry has grown and startups have become an appealing career choice we’ve filled out how-to guides for everything from fundraising to operations.

Alas all advice is specific to the giver’s experience and untangling biases to make advice relevant to your specific needs is quite hard. That’s where it helps to have more experienced operators on hand to call bullshit.

At chaotic.capital we pride ourselves on being investors who “have a guy” for even the most esoteric possible requests. Playbooks can only you so far when you need an expert.

Just in the last two days we’ve worked through how one hires a chief of staff, what to do when letting go of counsel who made a mistake, installing appropriate security procedures for digital footprints, and the resale brokers for a rare commodity.

We like to problem solve and the weirder the problem the more fun it can be. Removing obstacles and clearing bottlenecks is satisfying work. And knowing guy who knows a guy is a heck of a fun game of social geography.

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Media Startups

Day 1381 and Radical Responsibility

I thought the discourse around “founder mode” had died down but Kim Scott the author of the best selling book Radical Candor decided to link the meme to what she considers a so-called rise of “neo-authoritarianism” in Silicon Valley culture in an op-ed in the New York Times. Naturally it’s about Trump too.

My read on her thesis is that she has decided to use a technique she disavows in her own work; the frame of the piece is manipulative insincerity. It’s an unclear criticism being used for political gain.

She works to convince the reader that actually the most libertarian and individualistic demographic, who regularly decries state power (especially its use of coercion to drive censorship, limit transactions and restrict compute), are in fact, actually vouching for totalitarianism.

Gift Link to New York Times “How Founder Mode Explains the Rise of Trump in Silicon Valley

Even the graphic hints at the supposed appreciation of neo-monarchy as a nod to nRX intellectual Curtis Yarvin.

I fear she firmly missed the point of founder mode for her insincere political framing. Despite her clear understanding of our values.

In that original recipe, venture capitalists invested in founders rebelling against established hierarchy and building great products. And when those rebels themselves became too hierarchical, venture capitalists turned to new founders aspiring to overtake the old order.

She is right about we prefer to work as an industry and how we see our efforts. “Many of Silicon Valley’s greatest products were originally intended to liberate, not to control people.”

And yet missed she missed that founder mode is about liberating our founding teams from the suffocation of professional management. It’s got nothing at all to do with justifying tyrannical founders.

Rather founder mode is about limiting the tyranny of managers who can stymie progress despite having little personal responsibility for the success of the firm. In another world, she might have written a sequel called Radical Responsibility about fixing this problem.

Larger firms have a pantheon of corporate departments to ensure smooth governance from legal, to HR, to corporate communications in order to comply with state expectations.

As regulations have ballooned so too have the specialties required by the middle managers. We must be in compliance. We must take everything and every view into account. We must do things by the book.

Founder mode isn’t about running ripshod over your people. It’s certainly not about Trumpian declarations of what must be done. She’s absolutely correct that “emotional dysregulation, bullying and bloviating are not leadership attributes”

I find her criticism to be manipulative insincerity. She’s deliberately missed the point of the original Paul Graham essay, inserted her own political insinuations about how Silicon Valley is hiding their true preferences for authoritarians while herself advocating for a pass the buck culture. It’s not fit for Radical Candor and I’d expect better from someone of her stature.