I let myself get a little shook up by some poor health news early in the month. I’ve been pushing it physically all through 2024 as let’s be real it’s an exciting time. To fully capitalize on that acceleration we are all more focused on improving our health.
I’m taking action and optimistic about where we are headed with improvements in healthcare. I was able to rapidly iterate through options and set up surprisingly effective new treatments.
As we’ve work through the significant impact of the pandemic on our understanding of post viral illness and autoimmunity, we’ve had a more systems driven approach to testing interventions beyond pharmaceuticals reach more people.
Not that all pharmaceutical interventions are bad obviously as I’m lucky to have interleukin inhibitors in my life. I was able to find a new option with my doctor thanks to help from Claude and Perplexity.
And this progress is happening across all areas of medicine. I am also incredibly bullish on the benefits of GLP-1 inhibitors and their next generations. Inflammation and metabolism are intertwined in ways we can control barely articulate beyond “mind body connection” and yet we are developing the vocabulary.
The problems I am solving for myself teach me how we will allocate resources across many industries. The energy required to power artificial intelligence and the chips required to run those models will be pulled forward by our desire for solutions to living healthy lives
I scared someone really badly today. As I was being locked into the hard shell for my eighth hyperbaric chamber oxygen therapy session, I realized I had forgotten my chewing gum.
At 2 atmospheres of pressure it can be a real challenge to keep your ears from getting painfully congested. Even with yawning and blowing oxygen out your nose, it’s like going into an airplane with a sinus trouble. It’s uncomfortable but it can also be dangerous.
Careful. Equalize the pressure in your ears. If you feel your ears stuffy, equalize the pressure in the following ways. 1. Yawn 2. Swallow saliva. 3. Close mouth, pinch the nose, out of breath, blow the nose (all spelling mistakes theirs)
I got a little panicked as I was trying to stop the clinic technician from finishing the sealing process as I wasn’t sure if they could stop it once it was sealed or if I would need a full decompression cycle.
I was texting frantically “I forgot my gum can this be stopped ASAP so I can get it?”
I was tapping the window on the hardshell with a worried look and showing the text. I kept trying to make the font bigger and be clearer. FORGOT GUM OPEN?!
But it was confusing enough that everyone in the room thought something was seriously wrong. Which it would have been without the gum as I can’t do a full hour at 2 atmosphere without the help of the chewing. All the yawning, blowing out through the nose and other techniques aren’t quite enough.
It wasn’t yet an emergency. If it was I would have hit the big red button. But everyone seemed to think it was. After 2-3 minutes of frantic miscommunication it turned out that it was fine to open it up but we’d need to restart the seal and pressurize it again. I got the gum. And look who was on the TV screen.
I’ve been well controlled though my disease is not “inactive” or in remission. I manage it as it’s worth it to me to have a quality of life that includes working in technology as I want to be a part of making the tools that enable material progress in health.
Seeing things go in the wrong direction when my life is going in the right direction had a clarifying effect on me.
Not that I’ve been unaware that I must work at my health but rather it’s hard to always be working at health as it’s a matter of survival. But when you see a change in the data you act. I got serious and immediately went into action.
I’m so lucky to have to have access to an incredible community of biohackers. That I can ask someone who is studiously pursuing health in public is the best of the internet. I get the benefit of Bryan Johnson’s open sourcing his work. I’m doing an experiment with HBOT or hyperbaric chamber oxygen therapy and I learned from him I need it to be 2 atmospheres to be effective. This helps me plan and find hard chambers.
I can use Perplexity and Claude and even make my own personal assistant trained on my condition and my data is the remarkable thing.
I’ve found a new IL-17 inhibitor that looks to have twice the efficacy of my current one at the same dose. It was only approved in Europe but finally came on the American market. I was able to discuss it with my doctor immediately after going down a short question sequence on perplexity. You have so much power to improve your life now.
Shopping
I’d like to improve my V02 max and cardiovascular health in a way that works around my psoriatic arthritis and ankylosis. I have significant fatigue from the pain and obviously high impact isn’t in the cards for me. But I can try something like a DeskCycke. It’s even possible for me to do HIIT training with one. So I bought one. My goal is to improve my V02 by 10% in 8-12 months which shouldn’t be hard as mine is absolutely awful
I was extremely frustrated with an autoimmune reaction that got out of hand over New Year’s. I don’t care for taking corticosteroids as their side effects are quite severe even if they can be the only option when an immune response refuses to calm down.
To repair the damage, I went to a holistic clinic that offers a range of services like infrared saunas, IV therapies, cryotherapy and hyperbaric chambers.
I’ve got 8 more ahead of me along with some glutathione and vitamin IV drips so I’m hoping to be ship shape soon.
News and Sundries
The Chinese venture ecosystem has funds engaging in some suboptimal behaviors. They are clawing back personal assets, banning them from services and putting founders on no fly lists. Which is needless to say not the best way to encourage innovation.
Mark Zuckerberg is taking a new tack with speech at Meta. The company employing content moderators for what is true is out and enabling Twitter style community notes are in.
You ever push yourself so hard (physically, emotionally, mentally) that you crash afterwards? This is a common human experience. It’s called an altered window of immunity. Over exert yourself and you get sick.
I’ve come to understand the Christmas Break period as my yearly window of altered immunity. One reason I like to fast during the Holy Nights is to bring down my own physical and emotional reactivity.
When basic functions feel stressful and even small involuntary processes like digestion feel inflammatory then the work of living feels toxic. At that point one hopes rest is enough to get it out of your system.
The human tendency to ignore small problems until they become big problems is surely part of a wider cycle of disease. We wait to rest and repair till it’s too late and find ourselves crashing. For everyone bobbing along on the waves of life be sure to take a deep breath before plunging back under. It just might save your life.
I used to have a habit of extended fasting during the Holy Nights. I would fast for ten days between Christmas and New Years though never all the way through to Epiphany.
I have no special Christmas traditions beyond worship as my own family does not do gifts or gatherings. I prefer it this way. Quiet suits me now.
Advent is a season for reflection on the cycles of life. For me the time between Christmas and Epiphany is a rare season. Some consider it a liminal time or still point where the veil between physical and other realities are thin.
Holy Nights can be thought of as a still-point in earthly rhythms as we transition from Christ’s Birth to Epiphany. Northern European cultures call it this time the Raunächte or “rough nights” similarly it represents the thin point between worlds.
There are many traditions associated with this time. Cleaning and cleansing and warding off bad or unwanted energy, the paying off of debts and reconciliation as well as rituals of burning, cleansing and smudging. It’s a time for introspection and reflection.
I’ll likely meditate and journal as normal perhaps with some divination exercises. I enjoy any excuse to pull tarot cards and toss a Nordic rune.
I’m so unsure of how the next decade or two will play out. Anyone with a firm degree of certainty on the matter is suspect in my mind.
History is alive and material progress rests on the intelligent coordination of resources. We are in the middle of an explosion of intelligence. Will we rise to the challenge as a species?
I’ve had a wild year. I suspect many others feel similarly. The global year of elections exposed many tensions even as it resolved some questions of who has the power and how it will be used.
I’m more optimistic than I expected to be at the start of the year. We are living inside William Gibson’s Jackpot. As intelligence explodes and my own capacity to coordinate with others improves I am hopeful.
It’s Christmas Eve which puts me in a reflective mood. Changes in human nature are rare. If we change at all, it happens over generations of incorporating cultural change as it is combined with significant changes in technical and material circumstance.
Christ’s birth represents a significant cultural change for humans. From low circumstances arose a new way of living. The mighty see the grace of the meekest among us.
A quibble I have with modern industrial living is the prevalence of overhead lighting. I know we have to tolerate the bright lights in public and institutional spaces for reasons of cost, efficiency and clarity but why on earth have we found it to be acceptable in the home?
I’m grateful our divas bring their significant cultural gravitas to this debate. Bless Mariah Carey for leading the charge on this assault on the senses. I’ll let her not terribly articulate quote from a podcast speak the truth.
”I can’t with the overhead lighting. Why do they do it to us?,” Carey, 55, said. “But overhead lighting I don’t think so honey. Please stop it!…Everywhere I go, shut the lights! I don’t want to see them no more. Overhead lighting, it makes me sick.”
However it is relatively challenging to do cool focused lighting well. Yes it possible to do overhead track lighting in ways that bring focus and don’t overwhelm your senses. But it’s harder to do right.
You’d probably have to literally light Mariah Carey for a living to do it in a way that’s comfortable for someone with sensory issues. I developed migraines in my thirties and combined with my spectrum level sensitivity to noise, sound, taste and light I don’t need to push my luck. .
Given that us mere mortals without expert lighting design have to live comfortably, I fully stand by my preference for lamps and multiple light sources in my private spaces. It’s just going to be less of a headache. Literally.
If you light from overhead with bright cool tones bulbs so you can see the details I get it. I can’t fathom why I’d want that for anything but cooking, cleaning or sewing.
When the it’s time to relax and interact you are damn right I want a nice warm lamp. Now I’ve got double the lighting. No wonder the topic gives so many of us headaches.
Americans are in pain. Literally and emotionally. How that happened isn’t my focus. We are in the middle of a national conversation about the failures of institutional medicine and its relationship to our government. We are treading in deep water and it’s best not to get swept away.
There are many communities that have emerged on Twitter, Reddit, YouTube, GoodReads and elsewhere dedicated to the many paths available to go about fixing the problems in your life. There millions of strong communities of interests, hobbies, courses, and network knowledge that can enable you.
One of those communities is called TPOT. What is TPOT, who is in TPOT, what are its values and what does it believe are all involved and sometimes contentious questions. Being illegible is a big thing.
We mostly agree it stands for “this particular corner of Twitter” which is a loose network of nodes of people interested in applying knowledge they learn across our networked multimedia to their real life.
The experimental “you can just do things” attitude is a big tent. You see DIY projects, tutorials, reading lists, artificial intelligence and coding discussions, fitness and biohacking experiments, nutrition and cooking, meditation and nervous system research, pain management, psychology and emotional wellness and much more. You also see more far out woo woo topics like psychedelics, evolutionary psychology, and many flavors of rationalism and epistemology.
One of the most qualified voices to speak on TPOT might be Brook Bowman of Vibe Camp. In my understanding of her interpretation, TPOT is a memetic virus and once you touch it you are in the topology of TPOT for good.
tpot is this crazy memetic virus where the term itself means so little and is so contagious that you kind of become part of it just by hearing about it
Brooke
This is protective and makes it resilient. The network is bigger than any node and this is a good thing
So TPOT is best understood as a network composed of many interoperable nodes of interests and many layers of engagement. A memetic complex that you become part of on contact. If you read my blog it’s likely have many clear lines to TPOT.
If you like fitness, coding, rationalism, nutrition, or even home improvement well congratulations you are one or two nodes away from “just do things” as a life philosophy yourself and might be a member of TPOT yourself if you talk about it on Twitter.
And this is now some very dangerous semiotic territory as we cope with the gaping wound that is American health and murder. And I am concerned the narratives are going to be heavily fought over territory.
Because it’s easy to dislike a techbro right now. It’s pretty easy to dismiss the group. I can see it now. “Are your friends into this weird sounding acronym TPOT? Have you heard someone say “you can just do things?” If so you need to alert the authorities!”
Of course this sounds funny and histrionic. It’s totally normal to take responsibility for what you can in your life and try out ways of improving your life somewhat.
Everyone is dealing with pain (chronic or otherwise). Being an adult is a set of emotional challenges to manage and most of us do so by making the shocking decision to take action and do something. That doesn’t mean this world is is dangerous. It certainly doesn’t mean murder. It means doing something in your day life like lifting some weights, shipping some code, checking your biometric data, and trying to be a friend to lessen the pain most of us are in.
Like many fans of Star Trek, I am not at all ashamed of my affection for one of science fictions greatest franchises. I’m proud to love it.
When I visit San Francisco I like to rewatch the classic original series movie from 1986 “Star Trek: The Voyage Home” which is affectionately known as the whale movie.
Future San Francisco is a beautiful paradise where exceptional young people go to Star Fleet Academy. It’s fully automated luxury communism thanks to the not really military (but definitely feels like it) the United Federation of Planets.
The movie involves getting Spock back from previous escapades that had left him for dead. As they retrieve Spock a crisis is unfolding on earth.
A spacecraft is signaling to Earth alas no one can answer it. It disables everything near it. The Enterprise figure out that it’s whalesong and decide the only way to answer is going back in time to find Humpback whales.
The Reagan era was a strange one for environmentalist. The crew goes back in time to rescue Humpback whales and ends up in San Francisco in the 70s at least vibe wise. It was definitely a pop culture “save the whales” moment.
San Francisco was a mess in the past and everyone finds this to be relatable as a plot point though we all know it can be made a paradise.
We see nuclear vessels in Alameda as the brave future. We have to save our whales to save our future though. This was not a universe where environmentalists make the best villains. Environmentalists are the good guys which is almost sweet.
The Voyage Home is a ridiculous movie with a premise stuck in a bubble of social attitudes that is almost comforting.
Leaving San Francisco myself to voyage home myself makes me laugh at one of comedic bits of the movie. “I don’t know how these people made it out of the 20th century!”
To the skeptics I say a double dumb ass on you! Humans and their colorful metaphors might just might get us to the future after all. And San Francisco will be part of making it.
