Categories
Biohacking

Day 1912 and Informing Ourselves

Some 20 years ago, before I knew I’d have medical troubles of any length, my college job was working for a medical ethicist who was a physician with a grant to study informed consent.

Now, years later, as I have worked my way through institutional resistance to how I may come to be disabled and generally dismissed as a patient, I come to find that much of the skepticism my mother had as a crunchy hippie is now functionally being proved a quarter century on. These uncomfortable trends drives skepticism in even the most informed minds. And most patients can only ever be expert on their symptoms.

This comes at the end of a crisis of communication about the value of public health and personal responsibility in a community. Many people did not feel that they were given adequate consent and no longer trust anything said by doctors. Would most medical professionals agree they had informed consent? I think most argue they were. I agree.

Now of course we’re all desperately trying to prevent harms here and patients more than ever feel that, as they don’t trust what’s coming to them because we’ve not effectively decoupled population-level information from the individual human behind a given case. Is that informed consent? Yeah as best we can do it.

Now how does research play into all this? I also happen to have the misfortune of having working on the early years of on one of the worst medical misinformation spreaders in all of healthcare. I say this lovingly: it is Gwyneth Paltrow.

Now if you root around Twitter, you will find commentary about how the supplements hawked on Goop and the supplements hawked on various right-wing sites are functionally identical. But she got a lot right because she is a rich well connected white woman with money. So again who is informed and to what degree?

Unfortunately some of the things that are sold as treatments or supplements they sell are real and have proven out. We’re working our way through the science on our gut biome, infection and its links to preventable autoimmune diseases, and any number of other previously heretical paths.

But we’ve really not transformed the way we process our information on what we know and what is actually considered best practices. The gap is very wide. Like a chasm. I am way outside the norms because I fucked myself up believing I wouldn’t be a statistic as it mostly worked for most women.

So I live with issues. But do I think that people have a right to experiment with what we think might be snake oil? Absolutely. Everyone calculates their own risk. Heck Sarno is just one giant placebo doctor on letting go.

We know that some of the avenues of exploration will prove to be placebo effect if they work. And we still somewhat trust things that are actually going to cause harm aren’t really making it into the popular press and mass consumption unless there’s some evidence. I sort of believe that to be true.

More people should feel that they have the right, if they have informed themselves over a period of time as patients, to work around the system if they make no progress despite best efforts and years of work.

There’s just a lot to balance on being informed about your conditions and your capacity to manage your own health that is up to you. I think that generally speaking the paternalistic attitude has not produced superior outcomes.

And the quality of care I get as someone who can pay for health care anywhere in the world, it is galling to me that the gap between what we know and how far we can go in practice is so wide.

So let the guy advertise the doggy cancer vaccine because at least it’s teaching people that we have solutions to more than they know. They can judge risk reward and be a little bit strange. Humans are humans.

You get to decide it based on your own understanding of your own life and you get what you get. I was disabled by my own misjudgment of informed consent on treatments recommended by a COO of a major company who paid to have as a perk to her workforce. Egg freezing was an approved elective procedure that everyone was on board with ten years ago.

I was informed. I consented. I got it wrong. Now let me see if I can fix it in my own manner of choosing. And I won’t trust mere authority next time. Neither celebrity nor pharmaceutical company is to be trusted.

Categories
Aesthetics Politics Startups Travel

Day 1909 and All The Twinks Standing In The Line For The Bathroom

I am not an early riser, especially not when I’m out late for happy hours and dinners and the like. So I wasn’t planning on being at the 8am opening for the conference I’m attending in D.C amongst all the side programming.

I had a ten thirty talk I was particular excited to listen to as it was most salient to my work in artificial intelligence policy. Well, that was a dumb decision on my part. Not to arrive earlier.

I’ll take full responsibility for being a moron on that front, but I stood amongst a gaggle of gorgeous well dressed, well groomed and bright eyed young men hungry to build the world of the future. What a crowd of young people.

Being a chatty Cathy I asked about vintage Barbour jackets, bulldog ties, pocket squares, the merits of gel versus more advanced soft hold hair products, the declining quality of Moscot eyewear and other important topics to ambitious young men who are looksmaxxing to win the great game.

I didn’t have much else to do as the line was not moving. No one was getting in. Until people left no one was getting off the line. And that included others who had already been in and had their passes. The hottest ticket in town was perhaps a bit over capacity.

Someone rolled out a portable Starlink and we all piled in to tweet, chat, roll calls and (in my case) send tweets, Signal messages, and Slack channel responses. I got told my tweet about the two hour wait wasn’t ideal so I deleted it as I appreciate any attention to me running my mouth as I assume no one ever listens to me. I barely do.

But maybe I’m wrong? Last night checking into Butterworth’s, the woman manning check-in in lit up when I gave my name “I love your Twitter!” So maybe people do notice what I say. I still find that an a funny notion.

That said, it did take the full two hours to get into the giant event hall which made all the rush and planning a laugh. More people left the line and went back to work than stayed at 10am but everyone determined to participate seemed to make the best of it.

I asked if this was normal for a DC event and no one seemed to be from DC. So I didn’t get any good answers. This was an unexpected wrinkle that the venue was full was full up as an enormous crowd circled the block twice.

Since we remainders had decided to make the best of it we got to know each rather. Every man was quite a gentleman as we chatted oblivious to status till we were let in and others let us all know the pecking order. One of the young men I spent my wait, who is I learned later was literally the heir to one of the most important fortunes on the planet. Another was launching containerized autonomous weapons.

But that time of work and waiting was rather like being on an elevator stuck together, we might as well get to know each other. We are all equal before a tough door.

Thankfully we did get into the room before Jamie Dimon spoke. And he was the big boss of the handsome executive crowd.

I titled this “all the twinks standing in line for the bathroom” as yes a lot of handsome queer men were in attendance. But twink is an all purpose gender fluid aesthetic and not reflective of anyone’s sexual preferences.

And the line for the men’s y was a lot longer than the women’s. Ten to one ratios make me think this would be quite the dating scene for the ambitious woman.

But yes there are a lot of very well groomed young men in Washington D.C and everyone wants to build solutions for America. And being beautiful doesn’t hurt. To my single lady have you consider meeting a man in DC? Good odds and I doubt even a fraction of the twinks are gay.

Categories
Community Internet Culture Politics

Day 1903 and Ranting About Bentham

The tyranny of small differences can be the most vicious. I love vendettas in fashion and venture as they are connoisseurs of grievance.

Small communities with insular structures simmer embittered for years. You always know where someone, who is otherwise quite close to you, has committed a venal sin which cannot be forgiven.

But many times these small differences are actually the stuff of the breach. Once crossed you can never return. The opening cannot be closed without a great sacrifice. And these sacrifices are your character.

I am as well versed in the ridiculous schisms of my own affinity groups. As libertarians I’ll go on about the Cato libertarians, I’ll support my an-caps but I I’ll blood feud with the rest.

I feel this way about rationalists and the way they have introduced utilitarianism to Silicon Valley. And I want to be sympathetic here because there are aspects of effective altruism that are perfectly reasonable at first. I like prudent spending and reducing suffering with effective allocation.

But utilitarianism, taken to its end, has issues that anyone who has read Jeremy Bentham has to grapple with. The means do not justify the ends. We are all struggling with the horrors of the problems this creates in a modern society.

I saw the value of the manufactured meme campaign of effective acceleration as it oddly ended up dragging us to the middle. That was the intention and it achieved it. One can have many disagreements in the details.

However I do not think that political actors as far apart as Steve Bannon and MIRI agree on anything philosophically except “we want control over artificial intelligence so the people who are lesser than me can have no say.”

I cannot see how opposing forms of populist control can travel together without fear for character.

Everyone tries to be agreeable right up until coercive violence from Leviathan is required. And I guess some of you don’t think too hard about hard power huh?

I happen to find the request to have so much control over your fellow Americans to be an offensive view.

You think so little of the citizens of your own country when our core constitutional values require us to have so much more responsibility for ourselves?

I do think it is actually a moderate viewpoint that I believe in all of us. I believe in Americans no matter how stupid we can be. Remember that whole being a libertarian thing. I think personal responsibility requires more and Americans have delivered more despite our many failures.

I recognize that my personal stance here is not the final stance, especially as something of an outlier but because we have checks and balances, I know my involved citizenship demands that I declare where I stand.

Which is why the right to compute law that Montana adopted was a largely uncontroversial and popular when it was a bill. Before politics got involved, regular citizens, who were not whipped into a froth or frenzy, could understand that participating in the digital economy is crucial to living in the modern world.

It impacts our first, second, and fourth amendment rights directly because it demands we answer questions about property.

The wider existential issues on artificial intelligence do not get to be more important than our existing jurisprudence nor the opinions of our citizens.

The way we legislate and the value of our system of government, both state and federal, have a part to play. It’s funny the libertarian is making this argument I know, but it is a good revealed values exercise. Don’t get trapped by charlatans who have already declared that the ends justify the means. We both know they don’t.

Categories
Aesthetics Politics Startups

Day 1898 and Please Copy Our Homework

Today has been a very gratifying day for a very strange intersecting set of reasons. You may know that I have spent several years working to pass a “right to compute” law in Montana. It was signed into law in August of 2025 by Governor Gianforte.

I was so grateful that a campaign I initiated became not only become a bipartisan policy but a law supported by many Montana citizens & legislators. Now to see it go national not only model policy for the American Legislative Exchange Council but now have a second state, New Hampshire, pass it in their house, gives me indescribable joy.

Just forty eight more states to go. Though I believe it’s going to be an uphill climb as the topic of artificial intelligence has well and truly become politicized which makes stating simple cases of shared values much harder.

Except this isn’t really about artificial intelligence. Compute is a much broader and bigger thing than AI. It’s the stuff of the modern world. But that doesn’t mean we can’t apply what we know to be core American values as the lens through which we see it. Indeed it’s crucial we do.

Last year people could easily see that this was a sensible law that reflected our American values. Because of this sensible approach “the right to compute” is a winning coalition. It was bipartisan. So naturally it became a culture war.

I urge you not to adopt that frame. The right to compute speaks to American’s most cherished beliefs. Recognizing that it is not a novel legal theory. It is the application of the Constitution’s oldest commitments—to expression, to property, to liberty against government coercion

Even if you do not understand how all of its parts work, most understand that the entire digital world, in its constituent parts, is mathematics executed on physical hardware.

When government restricts computation, it does not merely regulate an industry. It restricts the tools through which people think, express themselves, and make use of their own property. Through that lens it’s clear we as Americans decide ourselves how to use it.

I hope we can remember this as the world changes and political actors look to change your mind. I do expect this to become a very complicated and uncomfortable position to have staked out.

Yet I feel confident that we will be able to make the case that this is not only the most American way of handling our future challenges, but is also practically the best way to bring abundance in a chaotic world. America is a land of reinvention that changes material conditions. We need not seek doom.

I believe that I have articulated that vision over the last five years of writing and investing so you can see my revealed preferences. I called our fund chaotic.capital for a reason. It’s hard, weird, difficult and scary but it’s also possible to be a lot better in the digital world such that we can use those gains to make the material world better. We can be more than productive primates with jobs

From nuclear energy to compute, this is what I believe and where I have put my time and money. We are organizing our world of atoms through the power of compute. And that can bring about a materially better world for everyone. Which I want.

I have been thrilled to see so many different people come together around the basic premise that we are empowered to do things.

We can lean in to the accelerating changes, all while holding fast to the reins of the values that built America, so that we may steer ourselves to material success.

Travis Kalanick of Uber may be among the best founders to have ever played the venture startup game. Today he has espoused our thesis & reinforced the work of my friends & founders. To see a cultural program written by a big coalition be part of his return to startup life (though he was never gone) is validating. We’ve found a rallying call.

The way forward is through the application of math on real problems. We can dramatically reimagine outcomes and the pace at which we do it. It’s scary and will look different but our grandparents lived through a lot of change too. Their grandparents as well. It’s the human condition.

I believe all of this is grounded in a philosophical foundation that is a recommitment to America’s core constitutional values. We are free to make things. And sometimes, when we apply ourselves, the world really does change.

If you are a canny socialist thinking look at this useful idiot for capital, I am honestly surprised that dialectical materialism has become so disliked by its own movement. If states with conservative libertarians can see that culture only changes when material conditions improve why don’t you want to improve them? Please feel free to copy our work as we have studied yours. You can find model policy here.

Categories
Politics Preparedness Startups

Day 1887 and Trust Me Bro

I don’t feel terrific so I’ll keep this as a ramble but with some links. I fear some sort of Rubicon has was crossed, which we will only recognize in hindsight, in the fight for property rights in America versus the tyranny of failing state capacity.

I am referring to the contract dispute between foundation model developer Anthropic and American Secretary of War Hegseth that boiled over on Friday night as some sort of Murderbot surveillance subplot parsed only by lawyers, policy wonks and anyone who remembers the patriotism of Chelsea Manning.

Right before America and Israel went all Epic Fury on Iran over the weekend, somehow it was felt a messy public fight between defense contractor and the civilian oversight of our military was ok? Good thing everyone is too distracted to care.

Funny how one can go from cheering on our military’s capacity for innovation one week and the next to be waving one’s arms screaming “no oh no no no” but that’s just politics as run by the instincts of reality television I suppose.

The best writing on this so far has been Dean Ball (who worked in this Trump administration on its AI position statement not so long ago) who feels that Hegseth took an approach on renegotiating a contract with a frontier AI model developer that has consequences.

Loosely and I am missing much Anthropic had its previous contract to parse classified documents in the Department of Defense (now the Department of War) negotiated by the prior administration. Some aspects of this contract wasn’t going to work for the Trump administration. Anthropic didn’t want to change it and Hegseth threatened to call Anthropic a supply chain risk unless it complied. They didn’t and Sam Altman signed a deal.

Wrapped up in this is that of course we all eventually comply with Leviathan who has the monopoly on violence. I don’t claim any expertise here but lots of people understand defense contractor law.

On its face Anthropic looks like the moral high ground and the position all capitalists and private property respected would prefer. However, it’s in Dean’s words, a bit weird for a company to tell the state that a private corporation has a say in policy as opposed to our democratic institutions.

Anthropic is essentially using the contractual vehicle to impose what feel less like technical constraints and more like policy constraints on the military

This is all complicated by the model developer having wishes for frontier AI development to be nationalized and for their work in particular to be safeguarded by a different political administration. It has become a right versus left thing as it was bound to do.

Now Anthropic gets to enjoy the full throated defense of its industry peers and even conservative policy makers like Dean, because our current state capacity is not what I’d call excellent when it comes to our civilian government capacity. Honestly our military still seems to be crushing it.

Secretary Hegseth looked a bit like he was over reaching in his command that he get his demands met. Americans are very touchy about surveillance of if’s citizens and much less touchy about autonomous weapons so it’s natural to be a bit suspicious if you are a millennial who remembers the Global War on Terror. If you are Zoomer who doesn’t know who Chelsea Manning is please go ask Claude.

However it’s not at all clear that Hegseth’s original negotiations were out of hand as of course it’s the state who decides legal use not the private company and we are meant to have laws, judicial process and all the rest. It’s just that we don’t. So what on earth do we do about it? Trust me bro is not a policy.

Categories
Medical Politics Preparedness

Day 1885 and Take It Down A Notch

The tension that has gripped geopolitics since the America build up began in the Middle East in late January, came to a dramatic head today.

A kerfuffle over the department of war’s contract to use the current best in class AI deployed on hyperscaler approved sandbox clouds naturally took up a lot of the energy the night before the real story got going. Great distraction work.

Iran launched large salvos of ballistic missiles and drones targeting U.S. bases across the Gulf and against the UAE, Qatar and Bahrain as part of a wider regional response.

The airspace being closed across the region, a lot of moving pieces at play means one can only pray for those in harm’s way. And that cooler heads can convince old generals not to use their youth for death.

I don’t feel all that well myself. I am glad to be far from the region. I have inflammatory symptoms popping up after my dental work but I hope it is soothed by antibiotics and now a dose of steroids.

I am itchier than seems sensible. I don’t know why but maybe general stress likes to compound itself with irruption.

I’d like to enjoy fair weather and beautiful sunsets before things change for the worse. I’ll do my best to work for things to go better but it’s a big job and we all must work towards it as best we can.

Categories
Medical

Day 1884 and Post Op Shop Bop On The Head

I am a stricken by the malaise that comes with minor injuries. Yesterday I had some dental work done (with a laser) and today is all wretched inflammation.

An affliction that requires recuperation gets me down as I can’t say I’m really miserable or in much. I live with worse pain whenever I flare with my ankyloysis. I just feel pretty shitty and my brain is slugging slowly through the muddy waters of stress toxins.

It’s m the mixture of stress, antibiotics (doctor recommended prophylactic course given my soft tissue infection risks of my biological injection) and the tide going out in the cortisol. Being flooded with cortisol is not just a meme.

And so I don’t recommend being this in this state, but you also need to do proper care and maintenance of things like healthcare. And your teeth are a core part of this. After a certain age you can’t just ignore problems. And so I’ll be on Twitter as I can’t concentrate well enough to do much useful today. And my husband will kill me if I do any more cosmetic shopping.

Categories
Chronic Disease

Day 1863 and Head Above Water

Yesterday I wrote that I had no gas in the tank. Today is not much better. I am barely keeping my head above the proverbial water line. I finished a major purchase which I thought would give me respite for a few days.

Alas changes in destination, an emergency dental appointment for a family member, and the promise of rest was more like a promise of fretful semi-consciousness.

After days of rushing around seem to have swept me off my feet and into bed I still am not quite rested.

I thought I was mended yesterday but it seems as if I’m on the second day of exaggerated sleeping patterns with long arcs of sleep in the wrong places and times. Add in a bit of overheating on top of it and something feels off.

It’s not unusual for me to absorb major changes and shifts throughout their unfolding via some migraine induced osmotic pressure. I feel the animal spirits and global vibes push in past my physical limits and I shut down. I hope I’ll reboot soon.

Categories
Finance Startups

Day 1858 and Parked Outside the Flow

The crazier the informational world gets, the more inclined I am to tune it all out. The flows of information are fun sure but it’s only useful to financiers, degenerates and the global management class. I really only rate into very bottom of one. No, not the degenerate class.

As 2026 has become the year of repositioning for “whatever is coming,” I am unsure of much I wish to return from the hinterlands into the flow. Being inside the flow looks enticing but it’s Thor the only way to do business.

The thing is that I began my own career by participating (in a small way) in what Will Manidis calls The Flow. Being inside has its perks and I saw a lot which enabled me to make some very good investments.

What is the flow? It’s a metaphor for a 24/7 club of information, a formal and informal circuit of social and business obligations, and series of social & professional inputs that sometimes generate spectacular output.

It’s no wonder people think investing looks like gambling when you put it that way. It takes a lot of shrewd social manners and access to resources to be inside the flow and those are distinct barriers for anyone outside the global ten percent.

So where to go if you are an American? Well, stay put somewhere you can be stable and secure. Sure the middle powers will tell you that they can save the liberal order but in reality it’s all state capitalism by strong man and technocrats. And I’m not either and I’d wager most truly new things that will matter won’t be easily secured by old mechanism of power.

What Manidis rightly points out in his Flow essay, is that you can build businesses and make good money for investors and limited partners outside of the flow. You can focus on your unique insights and build something great.

I hope I offer some proof of that myself. I flash the codes for my odd little node and traffic occasionally routes through me. I found crypto winners and the future of atomics outside the flow. And I think I’d rather like to spend my Sundays seeing what’s happening outside the nightclub of financial flows.

If you want to be outside you can be. I just might be already. You can find me in the proverbial parking lot of the Flow (the open internet) yapping, chilling, lighting and fighting with the cool kids. You will always know where to find me. I’ll be one DM away.

Categories
Emotional Work

Day 1853 and American Boomer Betrayal

I wish I could shake some of the grief that has gripped me over the past few months. I grieve the revelation of human truths I wish I did not know. And underneath the grief, I feel betrayed.

I feel betrayed by my elders, my country, its institutions and the power structures that have bounded my life and its path. It feels dramatic when I write it down but I know it to be true.

I have kept a lid on these simmering feelings because I am too afraid to unearth more truth that has the potential to rewrite my life and the internal (and external) perceptions of who I believe myself to be. And yet it is only change that has the power to overcome the entropy that destroys life. And that includes mine.

My feelings of betrayal seem too too ugly to look at and shake any sense of security or belonging that I might once have had. Which was in precious little supply already.

I don’t wish to be histrionic about it, but I am not the only American millennial who feels this way. I know many American Zoomers feel it more deeply than I do.

And there is plenty of evidence to support these feelings, which makes it all the worse. Feelings are not facts but there are facts beneath these emotions that are hard look at.

I don’t know why I cannot seem to unearth or articulate enough of my emotions to help me let go. I feel I have forgiven so much and it hasn’t been enough to change things. They say that betrayal creates a “double wound” as there is the act itself, and then the shattering of our belief in the fidelity and values that had scaffolded our lives.

I don’t want to look at the grief and betrayal straight on for reasons I hope I can slowly reveal to myself and others. Whatever protection it offers my ego and inner child must have some value but keeping things hidden is not helping me

I going to try to articulate these feelings, even if I am afraid of putting such enormous vulnerability out for scrutiny. I’ve done it before and it has only ever helped so I must find some courage to go further.

It’s not that I think anyone reads, or even notices what I say here, but rather once something is written into our public networks it stays. There is a reason “the word” has had such resonance for creation in faith. By writing it into a record I will create something that is real and will have consequences.

The relief I felt at the passing of my father at the end of last summer embarrassed me at first. I wanted to feel sadness, loss, love, and absence but all I could see was relief that he was gone.

I wished for more change and endings before the hungers of the past’s needs would eat more of my present. And I knew it would not come unless I made it so. Saturn devours his son. The son must slay his father.

I loved my father so deeply that I shaped my whole early life around impressing him in the hopes that he would find reason to be more present.

No achievement or milestone was ever enough to change his orientation and availability to me. Still I forgave him. He gave me so much. At the end I do not know (and must contend with not ever knowing) if he forgave himself.

This personal tragedy has anchored my feelings on the generation above mine and how they have conducted themselves in the management of America and all of its institutions.

The trust and fidelity has been broken. From education and health to politics, cultural and monetary systems the harms have compounded and the healing is slow. Family forgive but society needs scapegoats. And that makes me fearful.

The only systems that I feel has not actively betrayed me remain market capitalism and the edifice of our informational technologies. Ironically there are huge swathes of my generation who feel those are the systems that have harmed them the most.

I do not believe that free association and information are harmful. Indeed I see them as entirely beneficial even when there are obviously individual harms that the abstractions do not reveal so easily.

Some believe humans were simply not meant to live at a scale that showed us a world beyond our roots. How can we remain true to any values when all ruptured and greed, disgust, treachery and disloyalty is laid so bare and in such a brazen manner? To err is human and seeing our sins at such scale is a grievous harm we must overcome.

I myself am unsure if paradise lost to wider wisdom is only harm. We eat the fruit of the tree of the knowledge of good and evil and now see sin. But we also reveal the sustenance of divine love and redemption. Malus is not the same as malum.

Perhaps it is precisely because it is the wider world that has nurtured me even as family, elders, and institutions have ravaged the basics of life that I can see this horrifying but beautiful whole.

For millennia we have grounded the rituals and meaning of human life at a smaller scale with fewer hidden truths. Now it is laid bare to us all.

I am a citizen of the world with wealth but not health. I have built a beautiful family and marriage but likely will have no children. I have an incredible community of friends but we are scattered to the winds.

The personal middle ground of my life doesn’t exist because of the hunger of a generation and a nation that cared more about themselves and their reach and power than the future that would obviously arrive.

As younger generations wait to take the reins of their future, it threatens to never arrive. The grip of the past refuses to let go. And I wish to pry open that grip so we may try and do better.

They did the best that they could. And it hurts so much that it was not enough. The fear remains our efforts won’t be either.