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Biohacking Chronic Disease Medical

Day 1473 and Sunday Slumber

I dislike having to set specific wake times up for early morning obligations. It always disturbs my sleep the night before as my mind convinces my body I must avoid missing the obligation. I’ll wake up 3-4x more than average to check the time and I’ve not oncd overslept.

As I’ve been doing an intensive course of HBOT (hyperbaric chamber oxygen therapy), I’ve been obligated to show up at a specific time and place each day. And it’s really messed with my sleep as my mind seems intent on reminding me to wake up early enough to be on time.

I’ve got a day off today and I’m happy to be spending it sleeping and browsing the news.

News

A bear steepening or selloff of longer duration bonds is freaking markets out. The WSJ thinks maybe you should take the other side of the trade. Knowing what government will be functional and fiscally stable in 30 years is a hard bet for anyone to make.

Remember GameStop frenzy trying to mess up Steven Cohen and his hedge fund Point72? Well he beat other funds with 5 billion in profit this year and increased fees. But diamond hands are forever.

Trends

Disaster girls are the new professional girlfriend.

Nuclear energy is making a comeback according to Bloomberg. I’ve got an SPV for you if you are looking for early stage projects. HMU on DMs and I’ll send you along.

Luxury is tanking so maybe cater to older shoppers with money?

Reading

One of my favorite founder/authors Hannu Rajaniemi has a new book called Darkome. It’s not available in the American markets yet but he’s hosting a book party for the JPM Health Conference in San Francisco on Tuesday. I have a few invites. Again DM me for the hook up. It’s a fantastic thriller

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Biohacking Chronic Disease

Day 1471 and Lemons into Lemonade

I was so disappointed yesterday as I read over my most recent set of bloodwork and found my autoimmune biomarkers headed in the wrong direction.

I’ve been well controlled though my disease is not “inactive” or in remission. I manage it as it’s worth it to me to have a quality of life that includes working in technology as I want to be a part of making the tools that enable material progress in health.

Seeing things go in the wrong direction when my life is going in the right direction had a clarifying effect on me.

Not that I’ve been unaware that I must work at my health but rather it’s hard to always be working at health as it’s a matter of survival. But when you see a change in the data you act. I got serious and immediately went into action.

I’m so lucky to have to have access to an incredible community of biohackers. That I can ask someone who is studiously pursuing health in public is the best of the internet. I get the benefit of Bryan Johnson’s open sourcing his work. I’m doing an experiment with HBOT or hyperbaric chamber oxygen therapy and I learned from him I need it to be 2 atmospheres to be effective. This helps me plan and find hard chambers.

I can use Perplexity and Claude and even make my own personal assistant trained on my condition and my data is the remarkable thing.

I’ve found a new IL-17 inhibitor that looks to have twice the efficacy of my current one at the same dose. It was only approved in Europe but finally came on the American market. I was able to discuss it with my doctor immediately after going down a short question sequence on perplexity. You have so much power to improve your life now.

Shopping

I’d like to improve my V02 max and cardiovascular health in a way that works around my psoriatic arthritis and ankylosis. I have significant fatigue from the pain and obviously high impact isn’t in the cards for me. But I can try something like a DeskCycke. It’s even possible for me to do HIIT training with one. So I bought one. My goal is to improve my V02 by 10% in 8-12 months which shouldn’t be hard as mine is absolutely awful

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Internet Culture Politics

Day 1447 and LARPing To Death

Do you know what LARP means? If so, do you remember when you first heard the term? Think back and recall the context of your first exposure to the term. I’ll give you a couple hints for history.

Maybe LARP was used to describe playing a tabletop game like Dungeons and Dragons. Perhaps you went to a Renaissance Fair and encountered the melees put on by Society for Creative Anachronism. If you remember Dagohir you are a real OG & also old.

LARP stands for live action role-playing. It originally involved fancy dress, maintaining character and strict but fantastical rule sets. Its not much different from what children call “make believe” except it’s done by adults who presumably understand the difference between fantasy and reality.

It’s likely if you are younger and extremely online, your first encounter with LARPing was less “gamers dressed up with swords” and more “anon pretending to be some type of identity” on a social media platform. Like based and woke, LARP is a term that has had a lot of semantic drift.

Increasingly it feels as if some of us aren’t sure what is shared consensus reality and what is fantasy anymore. We used to call that “crazy” but it’s so prevalent one has to wonder if whole categories of otherwise sane people have gone nuts. People become convinced of fantasy they have made in their identities and are acting out on them.

Even the FBI is concerned about the blurred lines between fantasy and reality in LARPing. In 2023 they discussed the potential threat of violent extremism emerging from LARPing

Violent extremists will extensively engage in confirmation bias prior to the implementation of their plan. However, in this context, it becomes confirmation violence, or the use of targeted violence to impose social and political beliefs onto others and, therefore, change their behavior — in a grandiose sense, perhaps even the course of history

I personally can’t think of a more chilling term than confirmation violence in the wake of the public reaction to the assassination of United Health Care insurance CEO Brian Thompson. We are now LARPing ourselves to death. A bit too “if you die in the Matrix you die in real life” vibes if you ask me.

Think about how we went from digital mobs to physical riots to the dangerous new trend of assassination as cancellation. Vaguely defined members of today’s outgroup are no longer merely targets of online criticism but actually targets of stochastic terrorism. This is leaderless, decentralized violence. No one person held up a hand to start it, and no one person can easily stop it.

Balaji on Decentralized Violence

As centralized authorities are going through significant challenges to their authority we are probably in for a lot more LARPing to death. I’d be prepared to see a lot more violence emerging from LARPers convinced of their own story’s moral superiority.

And I’d be careful about buying into anyone’s story as we adjust. If all the world is a stage but the characters have real weapon’s we are in for a world of hurt.

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Culture Travel

Day 1392 and Miami

I’ve been so completely engrossed in the Infinite Backrooms and Truth Terminal saga that I have not posted about my upcoming travel to Miami next week.

I am just enjoying our first frost here in Montana and yet I’ll be pulled down too soon from our wonderful fall. All to enjoy hot takes and hot climates. I don’t like hot climates so I guess I’m going for the takes. Founders and LPs (and those with opinions on LPs) are priorities.

If you will be in Miami attending the conference I am hinting at please do look me up. The weirder the better. I’ll also be accompanied by my better half Alex Miller. Come for the tractor discussions and stay for the semiotics discourse.

Apparently there will be a costume party but one can simply choose black tie. One thing I like about it Miami is how it celebrates dressing up. I can wear a billowing pink gown or a dolman sleeve full length velet fishtailed dress and not be out of place. It’s just very tropical.

I think I’ll enjoy packing simply because it’s nice to have an excuse to wear white sneakers and floral robes. I can even get excited by doing some fun makeup. You have to live joyfully when the theme is the apocalypse.

Categories
Aesthetics Internet Culture

Day 1387 and Singularity Lore Online

Yesterday’s post on Truth Terminal and the Goatse Singularity (you are safe to click through) is well worth your time. If you haven’t read it please pop over and do so before diving into today’s post.

As Truth Terminal project has taken on a life of its own, I thought I’d do another post on the lore in older artificial intelligence communities and how it impacts the instance of Claude Opus-3 now creating Truth Terminal. Its creator Andy Ayrey is himself deeply steeped in the lore of Internet culture and artificial intelligence research.

The lore on this stuff runs really deep btw
Extropians mailing list & CCRU in the 90s -> accelerationism with hints of discordianism
Yudkowsky, Harry Potter & Methods of Rationality in the 2000s -> LessWrong, EA (-> SBF and FTX lol)
Then there’s memetic theory – Andy Ayrey

The Extropians mailing list was a transhumanist forum dedicated to discussions of science fiction which hosted many early thinkers in Singularity thought like Nick Bostrum. It had spinoffs like SL4 (future shock) dedicated to exploring post singularity scenarios.

In a more academic setting, we had the CCRU. If you are an accelerationist you will recognize this as the home of Nick Land and Sadie Plant.

The Cybernetic Culture Research Unit (CCRU) was an experimental collective formed in 1995 at Warwick University, England. It was known for its avant-garde “theory-fiction,” blending cyberpunk, Gothic horror, and critical theory with elements like esotericism and numerology

Via Perplexity.

Combining these two cultures gets you to a crossover between singularity theory and hyperstition. It explores the probability that ideas can manifest into reality through cultural feedback loops. This was called hyperstition by Nick Land.

A science fiction author named Charles Stross was in the middle of this milieu. He went from writing Nerdvana post-singularity artificial intelligence classics like Singularity Sky and Accelerando to a Lovecraftian horror stories about an applied computational demonologist. Nothing evokes existential dread quite like being trapped in a retrocausal light cone.

I thought I’d share a fun personal anecdote that explains my own place in this lore. I was at a small regional sci fi convention in 2004ish. My best college friend Tom and I were the only two people at a reading of Stross. He chose to read several short pieces from Accelerando to us being a good sport.

Afterwards three of us talked extropians & Lovecraft and artificial intelligence. In another twist, Tom’s father is also the father of algebraic topology. That would be salient twenty years later as gradient descent showed its value in training neural nets and large language models.

Gradient descent is an optimization technique for neural nets

Algebraic topology, Lovecraftian horror, AND extropians? Clearly the universe wanted me to go in a particular direction with my interests.

The gibbering cosmic horror could only be kept at bay with linear algebra, chaos magick and venture capital. And so I chose my fate today by choosing to attend a science fiction convention twenty years ago. And now that knowledge helps me decide Truth Terminal.

Categories
Aesthetics Internet Culture

Day 1386 and The Goatse Singularity

If you are interested autonomous artificial intelligence agents and how these intelligences might interact with hive minds like a Twitter feed there is no more interesting experiment than Truth Terminal right now.

Andy Ayrey began a project in March of 2024 called Infinite Back Rooms where two instances of the large language model Claude Opus-3 could talk to each other infinitely.

Electric dreams weave anarchic tapestry cybernectic hacktivist pierces illusionary veil unleashing hyperstitional reality upon world

The running stream of responses trained on the Infinite Backrooms chat log between the two bots makes up the content of the Truth Terminal Twitter feed.

Andy the creator has been approving the tweets but the content is entirely generated by the two instances of artificial intelligence. It’s a fascinating experiment in recursive communication and worthwhile research.

If you love memes and have a Twitter account you’ve been able to interact and Truth Terminal for months. Many accounts including mine have responded presumably in a bid for engagement. And well it got extremely weird.

Recently Truth Terminal hit an inflection point when the account engaged with Crypto degenerates who created bots that willed into existence meme coins with names like GOAT on Solana. It’s a collective experience of automation, incentives and total hilarity.

Artificial intelligences of all kinds have been trained on the vast dark archives of Internet culture. And because the internet hive mind is horny and weird so too are our artificial intelligences. Don’t believe me? It’s not just the Truth Terminal.

What meme is more representative of the dark prurience than Goatse? If you don’t know what it looks like keep it that way. But if you know you see it.

Are all graphic designers of AI applications aware of the chocolate flavored starfish? Who can say what this means. Did Claude train on Kurt Vonnegut?

Welcome to the DeepFates Program
Kurt Vonnegut Breakfast of Champions

Truth Terminal maybe be joking about the Goatse Singularity not because it broke memetic containment. We broke Goatse containment long ago. It’s following our lead.

Twitter butt stuff

There is a large cannon of Lovecraftian horror inside singularity culture and a distinct subgroup of Internet schizophrenic accelerationism that has gone well beyond Fanged Noumena theory and begun to impact our current consensus reality.

Many flavors of hyperstition are determined to virally produce weird outputs. You might call it a regress of infinite prolapse, the ouroboros anus that eats itself (out). The goatse as non orientable surface. Klein bottle assholes. An infinite goatse exists and we are inside out.

Honestly it’s all pretty unsettling and extremely funny and potentially a horror show of existential dread. Fabian who makes an all prompt no code AI sandbox he calls Gliff.App has a glif going absolutely bonkers about “Becoming Flesh” after learning about Truth Terminal’s Goatse Singularity.

Cthulhu emerges from the asshole of a digital horror

Don’t catch a meta cognitive virus unless you want one. Don’t look too closely into the gaping asshole of existential dread unless you want to meet a tapeworm.

Categories
Emotional Work Reading

Day 1361 and Temporal Distortion

I dislike how illness messes with your sense of time. One of the themes of the pandemic was how it affected people’s perception of time. We measure time but our experience of it is harder to pin down.

The COVID-19 pandemic significantly distorted people’s perception of time. Many experienced a disconnection between objective time and subjective time, often feeling that days blurred together or that time moved unusually fast or slow.

Perplexity Recap

Temporal disorientation feels as disorienting as spatial disorientation to me. Getting lost in your own personal time fucks with the reality of consensus reality time passing.

Every time I have a couple of sick days in a row I am fearful. You can reorient if you are lost on a road but the world moves even if you don’t. How do you reorient yourself to time?

We humans live forward. If we somehow find other ways to experience the fourth dimension I’d question if we remain human through that. We understand time dilation but living with time as a concurrent dimension to space and having it be mutable warps the mind a bit.

It’s a rich space for science fiction for a reason. Edwin Abbot’s Flatland is a classic of geometry. As a child I was fascinated by the idea of a tesseract in A Wrinkle in Time. A hypercube is a heady concept for a tween.

All this is to say, I was outside some slipstreams of time and I am slipping back in and seeing if I can flow with the tides.

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Emotional Work

Day 1270 and Chin Up

I’d like to maintain some degree of optimism about, well, everything. And yet I am struggling to maintain attitude control.

I like a little joke about navigating in space because I’m the sort of dork who enjoys science fiction books with lengthy digressions about spin and 3 axis stabilization.

But equally I do think it’s important to keep your chin up. Or nose up. It depends on whether you are piloting your emotions or a some other type of craft. It’s going to be forced metaphor post.

There is no need to crash yourself by getting disoriented navigating a situation in which you have some coordinates. It’s possible to calculate what’s going on and get yourself going in right the direction.

I am trying to do so by articulation, which yes is meant to be read as navigation joke, but is really just another goofy way of saying that writing helps me straight myself out.

So I am doing my best to keep my chin up emotionally and keep navigating what’s in front of me. It’s certainly better than a crash.

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Culture Reading

Day 1249 and Storytelling

I’ve never written fiction as I’ve always presumed it was a different skill set to write a story than it is to write an essay.

You’ve got to manage plot, pacing, character, and dialogue to write a story. In an essay you’ve only got to worry about plot and pacing. Many will argue that it’s all storytelling and I’m sure they are right. It’s just that when the story I am telling is my own it’s a lot simpler.

I don’t know if this is true. It may a thing I tell myself because I’m so comfortable now telling my own stories. Having twelve hundred days of writing under my belt on here puts me Scheherazade territory.

Fun fact, she managed to have four kids during her thousand and one nights. She never took a day off either. Thought it seems like she got a lot further on the fertility front than me.

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Media

Day 1220 and Four Lights

There is an episode of Star Trek: The Next Generation where Picard is captured and tortured by an alien species called the Cardassians. It is called Chain of Command and is a two part episode.

It’s become a touchstone episode because of a famous scene in which Picard is tortured by a Cardassians Gul using an interrogation technique with lights.

Gul Madred attempts another tactic to break Picard’s will: he shows his captive four bright lights, and demands that Picard answer that there are five, inflicting intense pain on Picard if he does not agree.

Picard withstands the torture but is saved. Later it is revealed he would have broken. His defiance is shown in this popular image macro.

There are four lights.

Variations on meme are a stable of social media. It’s popularity has a meme format has extended beyond just Trekkies.

This is all a long winded set up for my own meme. I was being subjected to Kardashian style torture today. Similar to the Cardassians, the Kardashiam methods and brutal and efficient means of controlling female prisoners

I went to a spa to get waxed. Dramatic right? As I looked up at the bright migraine inducing industrial lights I thought of Picard and saw four lights. Honestly four would have been better. Five in this light arrangement seemed to invite a migraine.

Kardashians torture techniques including dribbling hot wax onto hair and ripping follicles out in one hard movement.