Tag: Energy

Categories
Biohacking Chronic Disease

Day 1786 and 40 HBOT Sessions Later

The days becoming shorter has hurt my attempts at getting out in the sun for a walk every day. This matters to me as I’d like to get regular readings of my V02 maximum and my heart rate. I rushed out without sunscreen to get in a mile.

I hit an important milestone in my current biohacking regimen this week. I made it to my 40th session of hyperbaric oxygen chamber therapy or HBOT. I began on September 13th and did session 40 on November 20. I only traveled once during this period (a five day trip) so I could have fit it all in within a two month period but I was consistently doing two hours a day.

I intend to get bloodwork for comparisons next week, but in some ways this was a terribly experiment period. I had a small procedure to insert testosterone and estradiol into my left buttock which turned into a saga when I got a skin infection. Not the procedure’s fault and I’m glad I did it as my numbers are already better.

Fortunately HBOT is renowned for healing soft tissue infections so if I was going to suffer for having compromised immune health across my skin biome, then at least I had the state of the art treatment available.

We didn’t purchase the HBOT for its skin benefits. In fact, I didn’t even know I’d be have skin immunity issues. They began with my new IL-17 inhibitor which I started in January We’d acquired the HBOT around the same time but I had no idea how challenging Bimzelx would be. It could have gone worse.

We had originally acquired the HBOT as several of our friends and acquaintances had succeeded in managing impressive inflammation rate reductions as well as progress with a slew of autoimmune issues from long COVID to mold toxicity. The kind of troubles we only test in fancy labs with extreme athletes or the enterprising technology brother.

My wound has mostly healed save a small lump, my V02 max has improved despite virtually no exercise (hard to do much cardiovascular exercise with an infection in your posterior chain) and I have overall found the balance of improvement in my energy and pain to be significant.

Thanks for noticing Whoop

If I could just get a month without a health crisis where I have enough energy to workout consistently I just might make some progress. So if I disappear for a bit that will be what I’m doing. Once I’ve got bloodwork I will share obviously.

Categories
Politics Startups

Day 1784 and Strange Trade Offs

It’s been a pretty fantastic few weeks for my investments. Decisions made years ago are now looking pretty smart. A bet I made two years ago announced a round and then proceeded to announce splitting the atom the next week.

Not to only focus on current belle of the ball in Valar especially as everyone in the portfolio seems to be finding their way. We are lucky that we focused on compute, energy, and decentralization as that is the trifecta of the artificial intelligence wave.

I honestly didn’t expect that we’d see such progress in our nuclear pick. With the regulatory climate it seemed more likely compute marketplaces and inference products would outpace the most regulated technology in the world.

Somehow during a Trump administration you get unexpected outcomes. I’ve been fighting for compute figuring the energy bottleneck wouldn’t get addressed till we had the full supply side of new AI products. It turns out everyone wanted to rush into capital expenditures and infrastructure as the demand was already there.

I guess I’ve proved my own thesis again. You can get a read on the direction and maybe even first order effects but in a chaotic world the second and third order effects are much harder to predict.

And on balance for all the bad I think on balance the atomic age finally arriving might be a worth while trade for our future. Hard to say if I’ll keep that opinion but I am grateful America is getting back on track with nuclear power.

Categories
Preparedness Startups

Day 1783 and Good Days In Bad Times

I have spent a lot of time in various states of concern, sadness and frustration this year. Which is too bad, as so many incredible things have happened to me. We passed a right to compute law. Valar Atomics took “accelerate” way more seriously than most.

It’s hard to balance knowing the future won’t be anything like the past, but still having to make decisions made on that being the only data you’ve got. Engaging in governance and investing in energy seem like sensible ways of approach a strange future. Organizing energy is civilization 101 stuff.

I can predict a world with increasing chaos but how it will affect demand for things like energy, compute and decentralization are directional bets. You know it’s coming but how and when? And the downsides are hard to consider. Nobody ever thinks the entropy will apply to them but it’s already begun.

Every time future shock gets me I’m surprised I’m managing an imitation of Cayce Pollard at all. I’m practically a poster child for “sensible takes about various concerning challenges” as I get asked about various eccentric revealed preferences.

The Fourth Turning is coming about and we aren’t ready. I use short hand like the Churn, elite overproduction, The Sort and other minor terminologies and schools of thought to signal to others. I understand this to be my best way available way signal. But who knows as the humans retreat from shared networks it won’t stay that way.

Categories
Community Internet Culture

Day 1780 and Being Cooked

I’m starting to think the more optimistic you are about the future, the more cooked you think we are. I didn’t expect this.

The Doomers have a coherent worldview. It’s simple to imagine involving losing your humanity to machines. This is at least legible and a call to our common humanity. Change is scary and bad and we don’t know how any of this is going to go. So why not be cautious?

The optimists are all excited about different things though. And that opens us to a lot of attack paths. And yes I’m calling myself an optimist though I have a lot of downside scenarios on my radar.

Some of the outcomes that you might find dystopian are the utopian outcomes for someone else. Think Caliphates or Communist surveillance states.

The complexity of our reality is so far beyond the grasp of your average person it seems cruel. And we sympathize with the struggle to adapt because it appeals to our common humanity.

It’s no wonder America has had so many revivalist movements. We have changed so much in our 250 year history, we are always rediscovering the value of faith. What else do you have when the future is uncertain? If we are cooked anyways we may as well all take Pascal’s Wager?

Categories
Finance Startups

Day 1775 and It Is A Lot Easier To Just Be First

I often wonder how it is that venture capital remains so male-dominated when most of the work is the same skill set as a fashion editor or a style writer.

Sure, you occasionally see a man with good taste, and the twinks and gays are obviously the best of breed in both venture and fashion. But the game is basically the same. And yet fashion is dominated by women and venture as an esoteric sub-asset of private equity is very much not.

Let’s compare. Venture is a small, tight-knit group of people, who run on backchannels and gossip, and absolutely everything is determined by being the first person to land the next hot thing.

Now there is an avant garde who sets trends which then get validated with market success. In venture these are the earliest angel investors. In fashion, it’s the indie publishers who slog through the upstarts and pick who to champion.

The angel investor hopes their deal will go to later stage investors just as the trendsetting editor hopes their designer pick makes it to Vogue. Picking the next “it” thing and riding the wave to fortune is the goal for editor and designer, just as it is for investor and founder.

I personally think my skills are validated just as much being the person to get Mansur Gavriel added to the right boutiques as I am being the first check into Valar Atomics.

I took my bag to a breakfast at a boutique investment bank (you know the one with the summer camp) and happened to be meeting with an investor who loved the bag so much that the founder of their luxury ecommerce investment picked up the bag to stock immediately. Well over a decade later, I still carry that bag almost everyday and so do millions of other women.

Now ask yourself if this next story sounds pretty similar. I sent a direct message on Twitter to a young founder who seemed interesting. He had a quickness to his thought I respected as well as humility that set him apart.

Alas I didn’t like the company he was working on at the time and I didn’t like that he wasn’t its CEO. Sounds like “the food was bad & the portions are so small” sort complaint right? Well, I just thought he was so good he should be the lead in whatever he did next.

The young man had partnered with an experienced elder (which was probably wise for that industry) but the founder was clearly the dynamo in that situation. I told the founder that straight up. He had earned complete candor from me.

We began talking about what he really wanted to build. His intensity was awe inspiring. And his vision was just so crazy that I knew I had to back him. Many phone calls and strategy sessions later I wrote a check. It would take less time than I’d dared dream for others to see what I saw first.

Two years and change later, that young man is the founder and CEO of Valar Atomics which just raised 130 million dollars to make small modular nuclear reactors. Isaiah Taylor may have been a diamond in the rough when we first met, but I knew he’d sparkle in any setting.

To see him now as the jewel in the crowns of many much larger funds and backed by much more impressive and capable people than me feels amazing. I’ll always have the satisfaction of being the first to know he was going to be the next big thing.

And that’s not so very different from helping select the hottest hand bag of the last decade. Like Jeremy Irons’ character in finance classic Margin Call, I know the value of being first.

There are three ways to make a living in this business: be first, be smarter, or cheat.

Now, I don’t cheat. And although I like to think we have some pretty smart people in this building, it sure is a hell of a lot easier to just be first.”

If Isaiah’s work is successful, it will be an awful lot bigger than the hottest handbag. It will materially change the conditions of fueling our lives.

And while I am pretty smart, I knew enough to act first. Because it was a hell of a lot easier to just be first. And if I’m lucky, I’ll carry my bag and own equity in Valar for a long time to come. Read the full story in Bloomberg with a gift link.

Categories
Aesthetics Politics Preparedness

Day 1774 and Haywire Hell Handbaskets

It’s getting harder to ignore the crumbles. Everyone on the internet is furious about everything. And everyone offline is just trying to keep their heads down.

I should probably have the good sense to do so as well, but I’ve made my bones being accessible and not at all sure I know what happens in a post-human Internet. I want it to be a human directed future.

2025 as a year has been particularly challenging even though we’ve had some positive moments. More and more things are breaking and it’s just impossible to ignore no matter your insulation from reality.

And quite obviously, I have done more than average to move us as far from the center of Empire as is feasible. We moved to Montana.

Part of me thinks it’s well past time we really took a hard look at the hell in a hand basket direction we are headed in. Things are going haywire everywhere. The brief moment in which it felt like we might accelerate through the turn naturally goes splat if you don’t commit to the bit.

And part of me says fuck’em all. The shit that was done to me in the service of extracting my life force for what, pensions and healthcare costs for a generation who broke all social fabrics? It’s literally Saturn eating his son levels of disgusting.

And yet, I’m still unwilling to consider the centralized approach. We’d be eaten faster just like whales fished into oblivion by mistakes in the Soviet math.

It’s quite canny of Peter Thiel to be ahead of it and it’s a better look than insulting the spiritual leader of the Catholic Church. And I’m not a notably sympathetic person when it comes to institutions like the Church (being a Protestant and all). I’m more of a direct communion with the Lord type.

However when a man well versed in scapegoat theory puts out a sympathetic hand & his most significant rival makes the tactical error of insulting the Pope, you know the tilt-a-whirl is in full spin and there is little space for any of us to cling.

We are on the highway to hell, & I was promised a handbasket but there are none to be had as they’ve been hoarded. The fourth turning is about to show us that even the liberals get the boot. There is little doubt that I am mere scraps of elite overproduction that refused to fuse to my intended spot. I’ll find my own place to stand.

Categories
Biohacking Chronic Disease

Day 1764 and Not so Easy In and But Out of the Woods

It has been sixteen days since I confidently decided to insert testosterone pellets by tiny incision into my left buttocks. I was felt certain we’d checked all the appropriate risk factors and my tolerance threshold was met.

I felt I was making pretty decent progress on healing over five days as I had not only the benefits of HBOT but also read light therapy. I was pretty darn pleased and felt well.

And then it seemed I took a turn six days further on. Perhaps some trauma from the lidocaine and epinephrine induced enough of altered window of immunity that some bacterial weaseled its way in the wound and viola a subcutaneous infection called cellulitis.

I was put on two different antibiotics and we figured it would clear quickly. That was incorrect And it has been a slow healing process

Barely improving day by day. And I had somehow made the decision the night before the procedure that I would just waltz into a new beauty shopping blog as the holiday season warmed up. So that was perhaps bad luck on my part. And has slowed me down on something I was doing for some joy so I hope I didn’t let anyone down. I am muddling through.

Today I got an ultrasound on the wound after a fever spike and did a number of blood tests to see where my white blood cells and inflammatory markers were at.

The local hospital was having computer troubles which meant trouble scheduling an ultrasound but we managed to find another imagining clinic this morning.

Back at the hospital for bloods (they do walk ins for blood draws) they still appeared to be having issues with computers. “Your insurance isn’t recognized” was the verdict thirty minutes after using it at other lab. That made for a chuckle but we got it done.

The results are already in and we seem to be looking at healthy epithelial tissues and my CRP and Sed Rates were not elevated. Of course, half the reason I am worried is I take an immune suppressant for chronic autoimmune inflammatory condition.

It seems to manifest frequently as skin infections. My old drug wasn’t nearly as effective but it also didn’t have side effects. S

Hopefully slowly and with lots of protein and rest I’ll be healed and can spend my time on work and my pet beauty blog.

And tomorrow I’ll cross my 30th HBOT treatment mark so maybe it can make progress on building me up instead of dealing with a flesh wound. Which is actually just damned good luck on our part.

Categories
Politics

Day 1763 and Baumol’s Cost Disease Accelerationism

Today was a pretty big news day. It was a FOMC meeting with a cut, Jerome Powell gave some forward guidance that a cut in December is not guaranteed (cue market upset), and NVIDIA became worth $5 trillion.

This is apparently 16% of our GDP and without investment in artificial intelligence related build-out, our economy would have only grown by 0.6%.

Without Magnificent Seven spending, GDP would have grown at a mere 0.6% annualized rate instead of around 1.1%-1.2% – Fortune

So America would be looking about as gnarly as Europe without the Magnificent Seven and AI infrastructure build-out spending.

About 92% of GDP growth in the first half of 2025 was driven by investment in data centers, AI infrastructure, and information processing, with NVIDIA as a primary contributor Yahoo Finance

Which is a scary large amount for any corporation, but is somewhat rational in the logic of a civilizational technology changeover akin to the Industrial Revolution.

For some comparisons, Standard Oil at its height represented about 5-6% of the total U.S. stock market value at the time and 1.5% of America’s total GDP. AT&T’s Bell Systems were worth about 3-4% of America’s GDP at their asset peak in 1984 so not entirely an unprecedented situation though Nvidea’s percentage is a very networked era problem.

How afraid should we be about the potential for a market bubble in artificial intelligence? That is a questions for Carlotta Perez

Having lived through both the dot-com crash and the global financial crisis, I have some fears, but also this feels about as rational as any of the other ways we’ve handled valuations and value in past boom-and-bust cycles.

There is significant revenue from very real demand. It is just hard to see the demand as it’s industry demand not consumer. And the consumer demand we have is likely coming from professionals who are more enabled in ways we can’t count. I couldn’t have answered half the questions I had for this post before the LLM age.

And that demand for efficiency was coming and needed to be addressed over some time horizon, no matter what.

As different industries cope with their extreme lack of efficiency in the face of other industries who are efficient and in demand wages rise everywhere and basic needs like education & healthcare get more expensive despite not being delivered more efficiently.

So we still need those inefficient industries but what do we do? We have to find solutions.

Because we were going to need to build out the infrastructure for diversified energy transition. Much of this is being spent on build-outs for things that we genuinely need.

We need nuclear. We need power grids that aren’t from the dark ages. We need the efficiency for compute as government services have gone full runaway Baumol accelerationist. Unless we do the hard work that’s going to take 10 to 15 years, most liberal economies will collapse under the weight of the social safety net.

So we need to do a fairly thorough job of investing in the future, independent of whether it’s artificial intelligence driving our future or developing an industrial policy of, say, going to war with China. Necessity is the mother of invention and I’d rather the need be capital growth than war to drive industry.

I don’t know why this “facts of budgeting life” works people up so much. Booms and busts and bubbles build real things and we really need more efficient energy, healthcare, and education.

The economy is a nutrient gradient and money moves to where it gets fed. Right now the promised efficiency of a solution to unsustainable spending is paid for by gains in areas which did get more efficient. That is just the whole game. Grow faster and bring along anything that isn’t for the ride.

Categories
Aesthetics Biohacking

Day 1756 and Oops I Did It Again

Oh baby baby! So it seems as if, in my infinite wisdom, I did not pay enough attention to the early warning signs from my Whoop biometrics and I did indeed need to worry about the fun and games of a subcutaneous tissue infection.

I swear that this IL-17 inhibitor drives me nuts. Despite its impressive effect on my inflammatory biomarkers, it leaves me very susceptible to skin infections. And I have to be constantly vigilant to the first signs of an issue.

I’ll be fine. I did in fact catch it before it turned into anything serious. Where I am at it’s easily treatable with a short antibiotic course that may formerly be prophylactic. My wound area had not shown any signs of spreading nor was I running a fever or otherwise exhibiting other signs of serious infection.

I just had crappy HRV numbers and high resting heart rate three days in a row and it’s not worth risking it. I threw back some basic antibiotics last night and woke up with a normal heart rate again. My HRV is coming up just a little more slowly. Glad I didn’t wait as this isn’t worth any amount of risk to me.

I comforted myself by working on my beauty blog where I’ve got routines coming along for founding subscribers and a fresh post about Shrinkflation at Sephora and a minimalist men’s routine on sale at Amazon.

Retailers are a bit twitchy and everyone needs to be shopping early is the message we are getting everywhere. It’s a weird time. Or at least the retailers need to encourage the top 10%. So if that is interesting to you go subscribe as I’d love to have you in my strange beauty shopping blog meets the business of appearance.

Or if you are feeling adventurous for an honestly embarrassingly low fee I’ll put together a custom routine for you from my sample library or go full autistic and decant you the perfect mix of potions and lotions to meet you precise lifestyle and budget. My autistic obsession is your gain. It’s so much for me for and your skin will look amazing.

Categories
Biohacking

Day 1755 and Slow Healer

I am on a TMI roll this week so you will have to excuse this old blogger. If my n-of-1 experiments help even one woman struggling with her health, it’s worth it to me to embarrass myself in public by sharing the real details.

I’ve come consider this blog not just a personal experiment in daily writing, but my contributions to training the artificial intelligences of our future. I shall write women’s health into the Akashic records, even if I have to write every single day. Oh wait

Today I am moderately concerned about mg pace of healing and if I have contributed negative to it by increasing my strain modestly.

Yesterday I wrote “want to see something gross” about how maximalist approach to healing the incision site where we placed testosterone pellets.

I thought it was going pretty darn well and I had physical evidence with photographs to prove it. I did however have two days of poor biometrics which I had thought was a result of pushing myself physically a bit too hard while in my two days of menstruation. I

have rip-roaringly bad luteal phases (hence the exploratory hormone therapy to bring my testosterone to a normal baseline) but I have blessedly short menstruation that hits hard but doesn’t stick around. Aunt Flow knows she gets a weekend, and it ain’t a long one, before she has overstayed her welcome.

Now I’m going to show you something a lot worse than gross pictures of an incision site. I’m going to show you embarrassingly bad Whoop metrics. And now that I see them laid out I realize I probably should have asked my doctor earlier if I needed to go back on a prophylactic antibiotic just in case cellulitis was lurking. Like my god my HRV and heart rate are god awful right now.

Now they were a bit wonky this month but this is some danger Will Robinson territory. I honestly didn’t feel bad enough that I took it seriously.

I thought “eh Whoop has been sucking” for me. I thought this is just adjustment and the high heart rate is the testosterone is kicking in and my low HRV is just adjusting to finally having some energy. I feel genuinely energetic for the first time in years.

But today at a check up with another doctor they noted that I was at higher risk of developing cellulitis given my history over the summer with the abscess surgery and the panniculitus it had revealed. The side effects of the immune suppressive called Bimzelx I use as an inflammatory dampener seems to mostly manifest in skin infections. So either I’m just a slow healer and being paranoid or I’ve got to rock on with some amoxicillin to get the ill’in to stop.