Categories
Biohacking Medical

Day 1723 and Hormonal Rollercoaster Rides

We spent a long time at the doctor’s yesterday as Alex and I gutted it out with our excellent physician (with AI assists) through a myriad of different tests. We were attempting to figure out why he keeps getting respiratory infections and why I’m such a tasty treat to skin bacteria.

In truth, my basic inflammatory biometrics have improved so much on the new IL-17a inhibitor Bimzelx that it’s probably worth the hassle of occasionally having to slice open a random effected gland or abscess once a quarter. It’s just a shocking amount of work to do whack mole with pathology reports.

What I don’t seem to be able to improve is my low testosterone and the flavors of migraine headache that come with the roller coaster of my luteal phase. Which is presumably a clue and we are following it.

Astonishingly my lady hormones are in tip top shape. Though the “you should have no trouble getting pregnant if we can get off the medicines that stabilize you” remarks remains a heads trip. Yes I asked.

It is not a head trip that makes one’s husband enthusiastic about the prospect. Which is fair, as we have no family support, no backup plans for me regressing physically, and the family that does support us can’t get to America. So one can see why a CEO husband with sick investor wife who would have to give up work, plus potentially messed up baby, isn’t super appealing. Anyways! TFR is a fun topic.

I started with basic supplements in the precursor category like DHEA and STRO about a year ago when my testosterone came in at a 2 nanograms per deciliter (ng/dL) when it should be somewhere between 9 to 55 nanograms per deciliter (ng/dL). For context, adult men typically have levels in the 240–950 ng/dL.

The one sticky widget is that my testosterone remains stubbornly low. You wouldn’t think such a raging “see you next Tuesday” such as myself would be overburdened with the feminine hormones and lacking in ball buster hormones but I am.

I managed to eke it up to 5 with supplements and nutrition but it really didn’t match my otherwise excellent hormonal profile. Having ruined my chances at a healthy immune system when we tried the first half of IVF, I’ve spent some time working on and with my natural cycles.

Good information for all humans

I loathe being in my luteal phase but when I’m in my follicular phase I get 90% of my work done. We had presumed it was the rapid decline in estrogen and progesterone but maybe my floor rate testosterone was more of the issue.

For the past 8 weeks I’ve been using a testosterone cream that clicks up your dose and you rub it between your thighs. I know it’s gross. So I was curious to see where I might land. And praise the Lord I am now at 15 ng/dL. From 2 to 5 to 15 is some excellent progress but still below where we’d like me to hit. So we are going to run another test and try out the tiny pellets they slice into your skin. Since I’m already used to scalpels and antibiotics I figure why not?

Categories
Politics

Day 1712 and Rome Didn’t Collapse In A Day

This is one of the strangest weeks of the year for Americans. Labor Day marks the end of summer but it takes a bit to shake off the remains of the dog days.

Every day can jarring these days as whole world can narrow to a pinpoint with personal pain. Death will be stalking millenials as their parents age and die even as the money seems tilted in their favor with healthcare spending.

But as debts go up, investors price in risk and the state grapples with the turn and spend. It’s jarring to live as usual as change plays out in the personal and geopolitical.

I say Rome didn’t collapse in a day because anyone rushing for the exits doesn’t realize that change has surprising ways of reorganizing attention and power.

The week of 9/11 reminds Americans in particular. But the US Open closes and fashion week opens in New York and life finds a way.

It’s already playing out and we are all rearranging our lives and interests and families as we see whose time is sunsetting and who might be clever enough to ascend. I myself hope to thrive in the churn

Categories
Internet Culture Startups

Day 1707 and Putting Some GPU To Work

I try to give my own slight biological grey matter processing power a run every day through this writing habit.

I try to move my own body with walking, weight lifting and other condition so it can stay a somewhat workable machine. Tuning my body requires more work than tuning my mind as my brain rarely gives me issues but my tissues are always in some stage of revolt.

I have other assets behind my mind and my body. I’ve purchased a car. Precisely once and I have looked into buying others and shied away. My home doesn’t need to do work beyond housing me and my “disposable and durable” goods which range from a tractor other home appliances. A few of them do produce things for us like keeping our land and our laying hens.

We’ve got a gorgeous solar grid that generates electricity we can barely use. It goes into Bitcoin mining and stacking and running utilities but I’ll admit in a little lax about putting my our existing compute to work.

I’ll admit this is pretty stupid as we invest in crypto, we invest in hardware and energy, and we have invested in compute and inference networks. So why am I not doing more for passive yield on this?

Humans have been working as inference machines since we decided to keep records with something beyond the digits on our hands and the foot of our feudal lord.

Counting and abstractions being necessary for all sorts of engineering feats from cathedrals to graphical processing units. And now we have inference tokens just waiting to be brought down in cost as we bring networks online. So I am setting up my compute to be a part of those networks because sometimes it’s good to focus on little resource allocation problems to take your mind off tbh fe.

Categories
Medical Preparedness

Day 627 and First Responder

My hands are stained blood red. Despite a good scrubbing, my cuticles definitely show that I spent time packing wounds today. Ok, fake wounds. And it’s fake blood. I am taking a wilderness medical incident certification course. And it is very hands on. Literally.

A firefighter packing compressed gauze into a femoral artery simulator

I got the opportunity to take a spot in a course that one of my friends teaches. I’ve got so much exposure to medicine after the last several years of health challenges that I’ve been yearning to upgrade my knowledge to something more practical than my own personal biohacking. So when Tom offered up a spot in his medical incident certification course for wilderness response, I said you know what fuck it I’m going to do it.

And I’m so glad I did. Not because I anticipate needing to apply a tourniquet in the back country of Montana. Or that I’ll be faced with packing a groin wound to stop someone from bleeding out when they are hours away from the hospital. Though I am glad I now know how. But because I think hands on experience with a rougher world is experience I need to do my job investing in an increasingly complex, chaotic and unstable world.

I was absolutely enthralled by the first day. It was me and a bunch of other much more experienced EMTs, paramedics and wildfire fighters. I also met a number of extremely savvy folks who special in fire and emergency incident response.

I was very much thrown into the deep end of first responder world and I’m not ashamed to say I “died” on the very first scenario test as I’ve got no idea what I’m doing. But I’m soaking up as much information as I can as fast as I can. Though not quite as fast as arterial blood gushes. Yet. Ask me on Friday if I’ve improved.

I couldn’t tell you precisely why I think this kind of hands on exposure to emergency response is so crucial but something deep in my gut says that I cannot possibly invest in a changing world without having some on the ground exposure.

The folks who are fighting our worst wildfires and responding to our most intense natural disasters know something visceral about chaos and the fragility of modernity that the rest of us do a lot to suppress.

Just casual conversations as we went through lessons and practice opened up my mind to new areas of opportunity. I found half a dozen blind spots I didn’t know I had. The world is much more chaotic than the media and our social channels let on. But it’s also possible to tackle them head on. We are not helpless. And it’s not hopeless. And I’m feeling fully empowered to deepen my relationship to chaos as I learn just when and where I have more agency.