It has not been an easy year for me or my family. The struggle to find a path to a sustainable place of health feels harder than ever.
I am living in some type of thermodynamic hell. Everything I try comes with equally forceful reactions and I wish I could say more of them were positive.
Even when results look positive they have high costs that make me reconsider if I should have done it at all. Switching my immune suppression drug put my inflammatory markers in the best place we’ve seen them in years.
Alas it is so effective that I’ve had four major skin infections in 2025 of which four required going under the knife. And the fourth was caused by a small incision that was considered so safe and routine we almost didn’t consider antibiotics at all.
I just so badly want something to work in a way that doesn’t come with staggeringly high costs. Normally I’d link around to all the relevant posts but I just need a break so I’ll leave it as an exercise.
But can you imagine anything more depressing than having an infection on your ass? I sure can’t. I am stuck trying to keep pressure off of it while working on all the various projects of life and I am a slow healer.
I don’t even get to see if the HBOT is doing anything for my main concerns, as if it is we are only going to see it when I clear this crazy infection.
I suppose the good news is that one of the best treatments for high risk wound care is actually hyperbaric oxygen therapy so the positive and the negative are at least balanced.
Oh baby baby! So it seems as if, in my infinite wisdom, I did not pay enough attention to the early warning signs from my Whoop biometrics and I did indeed need to worry about the fun and games of a subcutaneous tissue infection.
I swear that this IL-17 inhibitor drives me nuts. Despite its impressive effect on my inflammatory biomarkers, it leaves me very susceptible to skin infections. And I have to be constantly vigilant to the first signs of an issue.
I’ll be fine. I did in fact catch it before it turned into anything serious. Where I am at it’s easily treatable with a short antibiotic course that may formerly be prophylactic. My wound area had not shown any signs of spreading nor was I running a fever or otherwise exhibiting other signs of serious infection.
I just had crappy HRV numbers and high resting heart rate three days in a row and it’s not worth risking it. I threw back some basic antibiotics last night and woke up with a normal heart rate again. My HRV is coming up just a little more slowly. Glad I didn’t wait as this isn’t worth any amount of risk to me.
I comforted myself by working on my beauty blog where I’ve got routines coming along for founding subscribers and a fresh post about Shrinkflation at Sephora and a minimalist men’s routine on sale at Amazon.
Or if you are feeling adventurous for an honestly embarrassingly low fee I’ll put together a custom routine for you from my sample library or go full autistic and decant you the perfect mix of potions and lotions to meet you precise lifestyle and budget. My autistic obsession is your gain. It’s so much for me for and your skin will look amazing.
I am on a TMI roll this week so you will have to excuse this old blogger. If my n-of-1 experiments help even one woman struggling with her health, it’s worth it to me to embarrass myself in public by sharing the real details.
I’ve come consider this blog not just a personal experiment in daily writing, but my contributions to training the artificial intelligences of our future. I shall write women’s health into the Akashic records, even if I have to write every single day. Oh wait
Today I am moderately concerned about mg pace of healing and if I have contributed negative to it by increasing my strain modestly.
I thought it was going pretty darn well and I had physical evidence with photographs to prove it. I did however have two days of poor biometrics which I had thought was a result of pushing myself physically a bit too hard while in my two days of menstruation. I
have rip-roaringly bad luteal phases (hence the exploratory hormone therapy to bring my testosterone to a normal baseline) but I have blessedly short menstruation that hits hard but doesn’t stick around. Aunt Flow knows she gets a weekend, and it ain’t a long one, before she has overstayed her welcome.
Now I’m going to show you something a lot worse than gross pictures of an incision site. I’m going to show you embarrassingly bad Whoop metrics. And now that I see them laid out I realize I probably should have asked my doctor earlier if I needed to go back on a prophylactic antibiotic just in case cellulitis was lurking. Like my god my HRV and heart rate are god awful right now.
Now they were a bit wonky this month but this is some danger Will Robinson territory. I honestly didn’t feel bad enough that I took it seriously.
I thought “eh Whoop has been sucking” for me. I thought this is just adjustment and the high heart rate is the testosterone is kicking in and my low HRV is just adjusting to finally having some energy. I feel genuinely energetic for the first time in years.
But today at a check up with another doctor they noted that I was at higher risk of developing cellulitis given my history over the summer with the abscess surgery and the panniculitus it had revealed. The side effects of the immune suppressive called Bimzelx I use as an inflammatory dampener seems to mostly manifest in skin infections. So either I’m just a slow healer and being paranoid or I’ve got to rock on with some amoxicillin to get the ill’in to stop.
Many moons ago, when I was first attempting to get a diagnosis for why I was always in pain and exhausted, I got a battery of allergy tests. I did the “gold standard of allergy testing” called patch testing which is a form of pin prick testing designed to pick up responses that may be delayed.
It was an awful experience. I barely made it through the 5 day trial between the 100 allergen pin pricks and final measurements.
I remember begging the doctor for a way to measure early. I asked if I could take some Benadryl to take the edge off. Alas the only way it would be accurate and covered by my insurance is if I gutted it out.
You are not allowed to shower, sweat, be exposed to UV rays (no going outside) or take immune suppressants that might subdue your body’s response.
I was struggling to breathe, my entire body itched and ached, and I had a migraine so bad I couldn’t see for the stars & dizziness. It’s possible I wasn’t stable enough to have adequately consented to the test but I did get my final results.
Out of 100 common allergens tested it was confirmed I was extremely allergic to 10 of them with another moderate sensitivity set of twenty or so that I should merely try to avoid as opposed to my firm “no go” list.
The dermatologist gave me a sheet with 75 different chemical names and formats that I might encounter in the wild from these core allergens:
I instructed to search ingredient lists for these names any time I purchased a household product, personal care item, cosmetic or other item which might include these ingredients which ranged from nail care to vaccines.
It was honestly quite overwhelming. And some of the above ingredients are in basically everything. I dare you to avoid Limonene for a month.
So my husband and one of our best friends did what any practical minded engineer would do and they made me simple Google sheet where all 75 varietals could be checked if I plugged in the ingredients from any item.
I used it for years. I’d plug in the INCI from every brand I encountered into the sheet no matter what. I gave away a lot of products to friends.
Today it occurred to Alex that we should probably vibe code the thing into a proper web application using Replit so other people could check ingredient lists for their own allergies.
You can set your own allergens or click a few buttons for common allergens and “clean ingredient standards” and run a check for an all clear.
It isn’t super fancy but it doesn’t need to be. It just needed to keep your data safe, be easy to log into so you can securely check and access your personal list and generally functional enough to change and set allergens. We’ve put it on our own little domain just to see how much this will cost to run (and we’ve set up alerts so it doesn’t go bonkers) but we figured this should be accessible and simple.
And while there are other options on the market, most are bloated, overly paranoid and designed for scaring California moms rather than quickly helping people with clear preferences for avoidance and actual tested allergies. So hopefully our pain can help you breathe easier.
Some options for chemicals and irritants you can select on our app. My own settings of allergies and sensitivities
I am pouring far too much autistic enthusiasm into my pet beauty shopping column that has a roughly half and half ration “theory of appearance culture in Protestantism” and half “specific routines at different price points” but I am enjoying it.
The heavier lift is going to be the work I am putting into the individual routines for the founding subscribers who have paid good money for help and I intend to give them my absolute all. I admit I’ve put way more thought than is probably necessary into each one but it’s a joy to track down specific products and geographic needs. It’s a shame that market editor was never a well paid enough job at a fashion magazine as I am pretty good at it.
Like, of course, I have opinions on the German drugstore market and its cost effective actives lines versus the old school naturals brands and where to acquire them. I don’t have quite as extensive a sample library of the market staples on hand but you know I spent hours browsing the grocery and retail shops when I was living in Frankfurt.
And on that note I’m going to bed early as I’m healing from my various biohacking experiments and I’m exhausted even with all the effort I’m putting into wound healing it still takes a certain about of rest to actually knit things together no matter how much time I spend with HBOT or what peptide stack I’m taking (it’s a spicy boy on the way in I’ll say that much).
We may have some room for improvement technique with it so I am encouraged if the is as bad as it gets. I am not seeing any benefits from it yet and ugly bruising and a bit of an opening on an incision isn’t so bad.
A lot will depend on how well I recover and how much the hormone actually helps when I’m not healing. I’m also in the luteal horrors phase where my hormones are most ridiculous so I’m curious to see the curve.
The best part of this remains that I have a world class treatment for skin wounds on hand. Hyperbaric chamber oxygen therapy’s best research has been in wound management from burns to slow healing diabetics. So if I have to nurse a wound doing it with oxygen at pressure is actually pretty baller.
And to make it even more on theme, I spent most of my time in there writing out a column on skincare and the Great Male Renunciation of Appearances as part of my beauty shopping column and excuse to write about the secret history of appearance and its power.
Every time life gets intense I wonder to myself why am I speeding into the turn? And then I look back at the last almost half decade (which is easier than I’d expected as I’ve written every day) and I feel the achingly slow pace at which we tackle the challenges of our lives.
We’ve had really big wins and really glass chewing teeth grinding bloody inch by inch progress that barely feels like a win at all.
Some pain has given me relief and some has been so heartbreaking it crushes me that it’s beyond my control. Bodies and borders are often beyond the control of mortals.
She had had teeny tiny testosterone pellets placed into her subcutaneous fat and had remarkable results in terms of energy and focus. This and that happened, and the summer was a mess, but today was the day I finally followed in her footsteps.
Vials of compounded testosterone
We’re started me with 10mg of estradiol (range 6-25mg with 8-10mg being most common), and 75mg of testosterone (range 50-150mg with the most common being 75-100).
We’ll aim for labs at 4-6 weeks after insertion which would represent peak levels. We will repeat dosing at 3-6 month intervals. We will check levels at 4 months or so, or earlier if I feel the effects waning.
Do be warned that within a paragraph or so, there will be images of needles, scalpels, and some blood. So feel free to not scroll down further.
Part of the difficulty with dosing this stuff is that the pellet doses are wonky and frequently out of stock – estradiol comes in 6mg and 10mg increments so 8mg is impossible.
Naturally, we’ve made surprisingly little progress when it comes to women’s health, particularly as it relates to hormones.
Prepared and ready to go
But as I am happy to be a guinea pig and my luteal phase is a mess of migraines and misery I figured I had little to lose and much to gain. I was the first patient my doctor has done the procedure on so if anyone in Bozeman is interested, you can confidently give it a go with him as I’ve survived it.
These cool tubes don’t actually go inside too far but sort of shoot the pellet into the incisions
I was given a local numbing agent with epinephrine. I needed a surprising amount of it but I was a bit nervous. Once I was just able to feel pressure and no pain it was time to make a small incision with a scalpel and in popped the tiny bit of hormone on the left butt cheek.
No big deal at all.
But if you don’t want to see it going in don’t scroll.
Just giving you space to turn back.
A tiny incision in my goose bumped bum with the little pellets easily tucked in
I am all bandaged up and still riding the cortisone of it all but I feel alright. I’ll be adding in progesterone orally to temper the estrogen as that’s another matter. I’m excited to report back on it as if I have even a fraction of Cate’s experience with it I’ll be quite happy. Also it’s about $70 a month so not cheap but not at all expensive for something that could potentially mitigate some long term issues I’ve struggled with for years.
I spent some time being really “in my special interest” today writing about why I think we should give more, and not less, time to beauty. I’ll post it to my new substack tomorrow as that will remain focused in subject matter.
Appearances clearly matter in every facet of life, but we don’t do much to help develop taste even as we face an onslaught of the hyper visual unrealistic world of short form video.
It’s all dopamine drips and quick hits that make it hard to develop taste of your own. At best you found algorithms that suited some things you could enjoy but sincerely held joy is rare. I’ve been able to experience many times and it’s now one keeps going in a cruel world.
I spent so much of my life beating the drumbeat of more access to the secret knowledge of the world only to discover again and again, that even if you offer up to the world pearls, not everyone will want them.
Or as my mother liked to say her Latin teacher said “I’m throwing pearl’s before swine!”
To appreciate the details is to recognize that layer upon layer of irritation worked to a finished pearlescent sheen which seems too delicate to truly show the process. That’s its beauty.
Each layer of culture is built by people who cares about details. And all kinds of details matter. Sometimes the details are financial. Sometimes aesthetic. Sometimes it’s noticing a very specific signal inside a very particular group and being able to admire the elegances.
I myself didn’t think I ever much went in for subtlety of any kind until I spent more of my time in mass markets. I’ve come to realize I was allowed to live without too much push on my own tastes for so much of my life.
And because I care about details, now I know I a stupid amount about the business of appearances because I worked at its heart.
I intend to do it as a fun addition to my life as I experience so much of life through professional and personal interest in technologies. I’ve got aspirations for a world where we choice to work to be better. That requires a world where beauty can be cultivated in improving ourselves. so you can be certain I appreciate the angles of how we use the existing culturally technologies at hand to create the new ones.
Now you might think all that walking around would leave your body feeling invigorated, and honestly it did, but we finished our grand tour by eating at the Costco food court. Now there are probably ways to eat healthy there but not how we did it.
We went for the classics including the dollar fifty hot dog and soda combination (a bulwark against inflation that has stood longer than seems possible) a slice of pepperoni pizza, a strawberry smoothie and a chocolate chip cookie. I had the pizza, some of the smoothie and half the cookie while Alex had the hotdog, a root beer, the rest of the smooth and a little bit of the cookie.
We didn’t feel immediately worse but we woke up today with what I’d qualify as a hangover. We can enjoy the above roasting as we generally don’t eat junk food and when we do it’s in more of the local beef category than the hyper processed and hyper preserved category.
Before you think this is a show of virtue, this preference never did anything for my aesthetics or metabolism, it’s just that it always makes me feel bad.
I am quite sensitive to preservatives and refuse to eat most forms of American bread and most varieties of prepared meal. No matter how good the ingredients are, the preservatives just do not agree with me.
It’s not that I’m a healthy eater naturally so much as hyper palatable foods are often hyper preserved foods and that sends my histamine response soaring into cytokine storms. So it’s no wonder I woke up feeling hungover.
I did real damage to myself as Bryan pointed out. We had a lovely time and I like to think the joy and happiness reduced our cortisol enough to bring us some balance. But it was easy to quit drinking for the same reason as it is easy to quit fast food. You feel like shit afterwards.
One of the most amusing fights I recall my parents having was my father taking my kindergarten class to tour a Carl’s Jr kitchen. They gave us a kid’s meal at the end, and while I turned up my nose at the burger, I did eat the french fried potatoes. My very crunchy and wise mother was not happy. “Now she will have a taste for French Fries!”
And damned if she wasn’t right. I still haven’t ever eaten a fast food hamburger. The idea of it is revolting to me and I’ve no clue how that came to be programmed in me. I may be one of the few people in America who has never eaten a Big Mac. But I love french fries. And good potatoes fried in a decent oil never leaves me feeling awful. But bread that doesn’t go moldy? That gives me a hangover every time.
